Chemokine (C-C Motif) Ligand 22 (CCL22) ELISA Kit for Human

Name: Human CCL22 ELISA Kit; Chemokine (C-C Motif) Ligand 22; MyBioSource
Brand: MyBioSource
SKU: MBS703248
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS703248

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for MDC has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any MDC present is bound by the… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

chemokine (C-C motif) ligand 22 (CCL22), ELISA Kit

Full Product Name

Human Macrophage-Derived Chemokine, MDC/CCL22 ELISA Kit

Product Gene Name

CCL22 elisa kit

Product Synonym Names

Human Macrophage-Derived Chemokine (MDC/CCL22) ELISA kit; A-152E5.1; ABCD-1; DC/B-CK; MDC; MGC34554; SCYA22; STCP-1; CC chemokine STCP-1; macrophage-derived chemokine; small inducible cytokine A22; small inducible cytokine subfamily A (Cys-Cys); member 22; sti; Human Macrophage-Derived Chemokine (MDC/CCL22)

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, plasma, cell culture supernates, tissue homogenates

Detection Range

15.625 pg/ml-1000 pg/ml

Sensitivity

10.324pg/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of Human CCL22. No significant cross-reactivity or interference between Human CCL22 and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.

Molecular Weight

10,625 Da

OMIM

602957

3D Structure

ModBase 3D Structure for O00626

Detection Wavelength

450 nm

Sample Volume

50-100ul

Protein Biological Process 1

Cytokine

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CCL22 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCL22 purchase

MBS703248 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the chemokine (C-C motif) ligand 22 (CCL22) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CCL22. The ELISA analytical biochemical technique of the MBS703248 kit is based on CCL22 antibody-CCL22 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CCL22 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CCL22. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CCL22. It may not necessarily be applicable to this product.

NCBI GI #

22538804

NCBI GeneID

6367

NCBI Accession #

NP_002981.2

UniProt Primary Accession #

O00626

UniProt Secondary Accession #

A0N0Q6; B2R4W2

UniProt Related Accession #

O00626

GenBank Nucleotide #

NM_002990.4

NCBI Official Full Name

C-C motif chemokine 22

NCBI Official Synonym Full Names

chemokine (C-C motif) ligand 22

NCBI Official Symbol

CCL22

NCBI Official Synonym Symbols

MDC; ABCD-1; SCYA22; STCP-1; DC/B-CK; A-152E5.1

UniProt Protein Name

C-C motif chemokine 22

UniProt Synonym Protein Names

CC chemokine STCP-1; MDC(1-69); Macrophage-derived chemokine; Small-inducible cytokine A22; Stimulated T-cell chemotactic protein 1Cleaved into the following 3 chains:MDC(3-69); MDC(5-69); MDC(7-69)

Protein Family

C-C motif chemokine

UniProt Gene Name

CCL22

UniProt Synonym Gene Names

MDC; SCYA22; A-152E5.1

UniProt Entry Name

CCL22_HUMAN

NCBI Protein Information

C-C motif chemokine 22; MDC(1-69); CC chemokine STCP-1; macrophage-derived chemokine; small inducible cytokine A22; small-inducible cytokine A22; stimulated T cell chemotactic protein 1; stimulated T-cell chemotactic protein 1; small inducible cytokine subfamily A (Cys-Cys), member 22

NCBI Summary for CCL22

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. [provided by RefSeq, Jul 2008]

UniProt Comments for CCL22

Function: May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.

Research Articles on CCL22

1. genetic polymorphism is not associated with breast carcinoma in Southern Iranian population

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CCL22 elisa kit

Reference Product	PubMed Publications
CCL17 elisa kit	>344 publications with CCL22 and CCL17
CCR4 elisa kit	>216 publications with CCL22 and CCR4
CXCR3 elisa kit	>43 publications with CCL22 and CXCR3
CCR5 elisa kit	>39 publications with CCL22 and CCR5
CCR7 elisa kit	>38 publications with CCL22 and CCR7
CCR3 elisa kit	>26 publications with CCL22 and CCR3
CCR8 elisa kit	>24 publications with CCL22 and CCR8
CCR1 elisa kit	>17 publications with CCL22 and CCR1
CCR2 elisa kit	>15 publications with CCL22 and CCR2

Pathways associated with CCL22 elisa kit

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram

Diseases associated with CCL22 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>183 publications with CCL22 and Inflammation
Hypersensitivity Antibodies	>140 publications with CCL22 and Hypersensitivity
Skin Diseases Antibodies	>120 publications with CCL22 and Skin Diseases
Respiratory Tract Diseases Antibodies	>115 publications with CCL22 and Respiratory Tract Diseases
Lung Diseases Antibodies	>99 publications with CCL22 and Lung Diseases
Necrosis Antibodies	>74 publications with CCL22 and Necrosis
Dermatitis, Atopic Antibodies	>67 publications with CCL22 and Dermatitis, Atopic
Respiratory Hypersensitivity Antibodies	>61 publications with CCL22 and Respiratory Hypersensitivity
Carcinoma Antibodies	>41 publications with CCL22 and Carcinoma
Pneumonia Antibodies	>16 publications with CCL22 and Pneumonia

Organs/Tissues associated with CCL22 elisa kit

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>13 publications with CCL22 and Bone
Connective Tissue Antibodies	>4 publications with CCL22 and Connective Tissue
Heart Antibodies	>3 publications with CCL22 and Heart
Muscle Antibodies	>3 publications with CCL22 and Muscle
Brain Antibodies	>3 publications with CCL22 and Brain
Vascular Antibodies	>2 publications with CCL22 and Vascular
Embryonic Tissue Antibodies	>2 publications with CCL22 and Embryonic Tissue
Ear Antibodies	>1 publications with CCL22 and Ear
Kidney Antibodies	>1 publications with CCL22 and Kidney
Umbilical Cord Antibodies	>1 publications with CCL22 and Umbilical Cord