Chemokine (C-C Motif) Ligand 27 (CCL27) ELISA Kit for Human

Name: Human CCL27 ELISA Kit; Chemokine (C-C Motif) Ligand 27; MyBioSource
Brand: MyBioSource
SKU: MBS704198
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS704198

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CLA has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CLA present is bound by the… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

chemokine (C-C motif) ligand 27 (CCL27), ELISA Kit

Full Product Name

Human cutaneous lymphocyte-associated antigen, CLA ELISA Kit

Product Gene Name

CCL27 elisa kit

Product Synonym Names

Human cutaneous lymphocyte-associated antigen; CLA ELISA Kit; ALP; CTACK; CTAK; ESKINE; ILC; PESKY; SCYA27; CC chemokine ILC; IL-11 Ralpha-locus chemokine; cutaneous T-cell attracting chemokine; skinkine; small inducible cytokine A27; small inducible cytokine subfa; Human cutaneous lymphocyte-associated antigen; CLA

Species Reactivity

Human

Assay Type

Sandwich

Detection Range

0.313ng/ml-20 ng/ml

Sensitivity

0.043ng/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of Human CCL27. No significant cross-reactivity or interference between Human CCL27 and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.

Molecular Weight

12,618 Da

OMIM

604833

3D Structure

ModBase 3D Structure for Q9Y4X3

Detection Wavelength

450 nm

Sample Volume

50-100ul

Protein Biological Process 1

Cytokine

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CCL27 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCL27 purchase

MBS704198 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the chemokine (C-C motif) ligand 27 (CCL27) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CCL27. The ELISA analytical biochemical technique of the MBS704198 kit is based on CCL27 antibody-CCL27 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CCL27 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CCL27. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CCL27. It may not necessarily be applicable to this product.

NCBI GI #

5730035

NCBI GeneID

10850

NCBI Accession #

NP_006655.1

UniProt Primary Accession #

Q9Y4X3

UniProt Related Accession #

Q9Y4X3

GenBank Nucleotide #

NM_006664.2

NCBI Official Full Name

C-C motif chemokine 27

NCBI Official Synonym Full Names

chemokine (C-C motif) ligand 27

NCBI Official Symbol

CCL27

NCBI Official Synonym Symbols

ALP; ILC; CTAK; CTACK; PESKY; ESKINE; SCYA27

UniProt Protein Name

C-C motif chemokine 27

UniProt Synonym Protein Names

CC chemokine ILC; Cutaneous T-cell-attracting chemokine; CTACK; ESkine; IL-11 R-alpha-locus chemokine; Skinkine; Small-inducible cytokine A27

Protein Family

C-C motif chemokine

UniProt Gene Name

CCL27

UniProt Synonym Gene Names

ILC; SCYA27; CTACK

UniProt Entry Name

CCL27_HUMAN

NCBI Protein Information

C-C motif chemokine 27; skinkine; CC chemokine ILC; IL-11 Ralpha-locus chemokine; small-inducible cytokine A27; IL-11 R-alpha-locus chemokine; cutaneous T-cell attracting chemokine; cutaneous T-cell-attracting chemokine; small inducible cytokine subfamily A (Cys-Cys), member 27

NCBI Summary for CCL27

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Jul 2008]

UniProt Comments for CCL27

Function: Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10.

Research Articles on CCL27

1. We show that the adult but not prenatal human keratinocytes produce and release large amounts of CCL27.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CCL27 elisa kit

Reference Product	PubMed Publications
CCR10 elisa kit	>60 publications with CCL27 and CCR10
CCL20 elisa kit	>21 publications with CCL27 and CCL20
CXCL10 elisa kit	>20 publications with CCL27 and CXCL10
CCR7 elisa kit	>15 publications with CCL27 and CCR7
CCL21 elisa kit	>14 publications with CCL27 and CCL21
CCR6 elisa kit	>5 publications with CCL27 and CCR6
CCR5 elisa kit	>5 publications with CCL27 and CCR5
CCL25 elisa kit	>5 publications with CCL27 and CCL25
CCBP2 elisa kit	>4 publications with CCL27 and CCBP2
CXCR5 elisa kit	>1 publications with CCL27 and CXCR5

Pathways associated with CCL27 elisa kit

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram

Diseases associated with CCL27 elisa kit

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>55 publications with CCL27 and Immune System Diseases
Inflammation Antibodies	>45 publications with CCL27 and Inflammation
Necrosis Antibodies	>33 publications with CCL27 and Necrosis
Skin Neoplasms Antibodies	>16 publications with CCL27 and Skin Neoplasms
Disease Models, Animal Antibodies	>11 publications with CCL27 and Disease Models, Animal
Dermatitis, Allergic Contact Antibodies	>11 publications with CCL27 and Dermatitis, Allergic Contact
Drug-Related Side Effects and Adverse Reactions Antibodies	>6 publications with CCL27 and Drug-Related Side Effects and Adverse Reactions
Nervous System Diseases Antibodies	>5 publications with CCL27 and Nervous System Diseases
Liver Diseases Antibodies	>3 publications with CCL27 and Liver Diseases
Precancerous Conditions Antibodies	>2 publications with CCL27 and Precancerous Conditions

Organs/Tissues associated with CCL27 elisa kit

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>5 publications with CCL27 and Lung
Testis Antibodies	>2 publications with CCL27 and Testis
Connective Tissue Antibodies	>2 publications with CCL27 and Connective Tissue
Placenta Antibodies	>2 publications with CCL27 and Placenta
Eye Antibodies	>1 publications with CCL27 and Eye