Natriuretic Peptide Precursor B (NPPB) ELISA Kit for Mouse

Name: Mouse NPPB ELISA Kit; Natriuretic Peptide Precursor B; MyBioSource
Brand: MyBioSource
SKU: MBS704926
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS704926

MBS704926 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the natriuretic peptide precursor B (NPPB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

natriuretic peptide precursor B (NPPB), ELISA Kit

Full Product Name

Mouse brain natriuretic peptide, BNP ELISA Kit

Product Gene Name

NPPB elisa kit

Product Synonym Names

Mouse brain natriuretic peptide; BNP ELISA Kit; BNP; brain type natriuretic peptide; natriuretic protein; natriuretic peptide precursor B

Species Reactivity

Mouse

Samples

Serum, plasma, tissue homogenates, cell culture supernates

Detection Range

6.25 pg/ml-400 pg/ml

Sensitivity

1.56 pg/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of Mouse NPPB. No significant cross-reactivity or interference between Mouse NPPB and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.

Molecular Weight

13,756 Da

3D Structure

ModBase 3D Structure for P40753

Detection Wavelength

450 nm

Sample Volume

50-100ul

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of NPPB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NPPB. It may not necessarily be applicable to this product.

NCBI GI #

565671787

NCBI GeneID

18158

NCBI Accession #

NP_001274277.1

UniProt Primary Accession #

P40753

UniProt Related Accession #

P40753

GenBank Nucleotide #

NM_001287348.1

NCBI Official Full Name

natriuretic peptides B isoform 2

NCBI Official Synonym Full Names

natriuretic peptide type B

NCBI Official Symbol

Nppb

NCBI Official Synonym Symbols

BNF; BNP; AA408272

UniProt Protein Name

Natriuretic peptides B

UniProt Synonym Protein Names

Gamma-brain natriuretic peptideCleaved into the following chain:Brain natriuretic peptide; BNP

Protein Family

Brain natriuretic peptide

UniProt Gene Name

Nppb

UniProt Synonym Gene Names

BNP

UniProt Entry Name

ANFB_MOUSE

NCBI Protein Information

natriuretic peptides B; brain natriuretic peptide; type-B natriuretic factor; gamma-brain natriuretic peptide; natriuretic peptide precursor type B

NCBI Summary for NPPB

This gene encodes a secreted protein that belongs to the family of natriuretic peptides. Its precursor protein is processed to generate the active mature peptide. The mature peptide is a cardiac hormone that plays a role in ventricular remodeling as well as blood pressure regulation. Mice lacking this gene exhibit cardiac fibrosis. In humans this gene is associated with congestive heart failure, low bone-mineral density and postmenopausal osteoporosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]

UniProt Comments for NPPB

Function: Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.

Research Articles on NPPB

1. Data indicate that the identified stress-responsive enhancer of Nppa and Nppb, the most common markers of heart failure, is a 650-bp fragment within 50 kb of the Nppa and Nppb loci.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NPPB elisa kit

Reference Product	PubMed Publications
Nppa elisa kit	>37 publications with NPPB and Nppa
Nppc elisa kit	>6 publications with NPPB and Nppc
Npr3 elisa kit	>5 publications with NPPB and Npr3
Myh6 elisa kit	>4 publications with NPPB and Myh6
Tnni3 elisa kit	>2 publications with NPPB and Tnni3
Ctgf elisa kit	>2 publications with NPPB and Ctgf
Pln elisa kit	>1 publications with NPPB and Pln
Agt elisa kit	>1 publications with NPPB and Agt

Pathways associated with NPPB elisa kit

Products by Pathway	Pathway Diagram
MicroRNAs In Cardiomyocyte Hypertrophy Pathway antibodies	MicroRNAs In Cardiomyocyte Hypertrophy Pathway Diagram
PluriNetWork Pathway antibodies	PluriNetWork Pathway Diagram
CGMP-PKG Signaling Pathway antibodies	CGMP-PKG Signaling Pathway Diagram
CGMP-PKG Signaling Pathway antibodies	CGMP-PKG Signaling Pathway Diagram

Diseases associated with NPPB elisa kit

Disease Name	Pubmed Publications
Fibrosis Antibodies	>138 publications with NPPB and Fibrosis
Cardiovascular Diseases Antibodies	>72 publications with NPPB and Cardiovascular Diseases
Heart Diseases Antibodies	>36 publications with NPPB and Heart Diseases
Hypertension Antibodies	>26 publications with NPPB and Hypertension
Hypertrophy Antibodies	>18 publications with NPPB and Hypertrophy
Edema Antibodies	>15 publications with NPPB and Edema
Heart Failure Antibodies	>15 publications with NPPB and Heart Failure
Inflammation Antibodies	>14 publications with NPPB and Inflammation
Necrosis Antibodies	>13 publications with NPPB and Necrosis
Postoperative Complications Antibodies	>12 publications with NPPB and Postoperative Complications

Organs/Tissues associated with NPPB elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>134 publications with NPPB and Brain
Heart Antibodies	>84 publications with NPPB and Heart
Embryonic Tissue Antibodies	>15 publications with NPPB and Embryonic Tissue
Testis Antibodies	>1 publications with NPPB and Testis