Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) ELISA Kit for Human

Name: Human GRIN1 ELISA Kit; MyBioSource
Brand: MyBioSource
SKU: MBS706259
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS706259

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for GRIN1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any GRIN1 present is bound by the… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1), ELISA Kit

Full Product Name

Human Glutamate [NMDA] receptor subunit zeta-1, GRIN1 ELISA Kit

Product Gene Name

GRIN1 elisa kit

Product Synonym Names

Human Glutamate [NMDA] receptor subunit zeta-1 (GRIN1) ELISA kit; NMDA1; NMDAR1; NR1; N-methyl-D-aspartate receptor channel; subunit zeta-1; NMDA receptor 1; glutamate [NMDA] receptor subunit zeta 1; glutamate receptor; ionotropic; N-methyl D-aspartate 1

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Samples

Serum, plasma, tissue homogenates, cell lysates

Detection Range

125 pg/ml-8000 pg/ml

Sensitivity

< 31.25 pg/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of human GRIN1. No significant cross-reactivity or interference between human GRIN1 and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Inter-assay Precision

Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.

Molecular Weight

105,373 Da

OMIM

gene 614254

3D Structure

ModBase 3D Structure for Q05586

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GRIN1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GRIN1 purchase

MBS706259 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GRIN1. The ELISA analytical biochemical technique of the MBS706259 kit is based on GRIN1 antibody-GRIN1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GRIN1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GRIN1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for GRIN1. It may not necessarily be applicable to this product.

NCBI GI #

11496971

NCBI GeneID

2902

NCBI Accession #

NP_000823.4

UniProt Primary Accession #

Q05586

UniProt Secondary Accession #

P35437; Q12867; Q12868; Q5VSF3; Q5VSF4; Q5VSF5; Q5VSF6; Q5VSF7; A6NLK7; A6NLR1; C9K0X1

UniProt Related Accession #

Q05586

GenBank Nucleotide #

NM_000832.6

NCBI Official Full Name

glutamate receptor ionotropic, NMDA 1 isoform NR1-1

NCBI Official Synonym Full Names

glutamate receptor, ionotropic, N-methyl D-aspartate 1

NCBI Official Symbol

GRIN1

NCBI Official Synonym Symbols

NR1; MRD8; GluN1; NMDA1; NMDAR1

UniProt Protein Name

Glutamate receptor ionotropic, NMDA 1

UniProt Synonym Protein Names

Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMD-R1

Protein Family

Glutamate receptor ionotropic

UniProt Gene Name

GRIN1

UniProt Synonym Gene Names

NMDAR1; GluN1; NMD-R1

UniProt Entry Name

NMDZ1_HUMAN

NCBI Protein Information

glutamate receptor ionotropic, NMDA 1; NMD-R1; glutamate [NMDA] receptor subunit zeta 1; glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; N-methyl-D-aspartate receptor channel, subunit zeta-1

NCBI Summary for GRIN1

The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

UniProt Comments for GRIN1

Function: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors

Research Articles on GRIN1

1. The rs1126442, GRIN1 polymorphism contributes to the genetic vulnerability to psychosis in METH-dependent subjects in the Thai population.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GRIN1 elisa kit

Reference Product	PubMed Publications
FLNA elisa kit	>12 publications with GRIN1 and FLNA

Pathways associated with GRIN1 elisa kit

Products by Pathway	Pathway Diagram
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Diseases associated with GRIN1 elisa kit

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>23 publications with GRIN1 and Nervous System Diseases
Brain Diseases Antibodies	>14 publications with GRIN1 and Brain Diseases
Disease Models, Animal Antibodies	>8 publications with GRIN1 and Disease Models, Animal
Memory Disorders Antibodies	>5 publications with GRIN1 and Memory Disorders
Nerve Degeneration Antibodies	>5 publications with GRIN1 and Nerve Degeneration
Movement Disorders Antibodies	>4 publications with GRIN1 and Movement Disorders
Learning Disorders Antibodies	>4 publications with GRIN1 and Learning Disorders
Pain Antibodies	>4 publications with GRIN1 and Pain
Poisoning Antibodies	>3 publications with GRIN1 and Poisoning
Seizures Antibodies	>3 publications with GRIN1 and Seizures

Organs/Tissues associated with GRIN1 elisa kit

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>13 publications with GRIN1 and Bone
Connective Tissue Antibodies	>4 publications with GRIN1 and Connective Tissue
Heart Antibodies	>3 publications with GRIN1 and Heart
Muscle Antibodies	>3 publications with GRIN1 and Muscle
Brain Antibodies	>3 publications with GRIN1 and Brain
Vascular Antibodies	>2 publications with GRIN1 and Vascular
Embryonic Tissue Antibodies	>2 publications with GRIN1 and Embryonic Tissue
Ear Antibodies	>1 publications with GRIN1 and Ear
Kidney Antibodies	>1 publications with GRIN1 and Kidney
Umbilical Cord Antibodies	>1 publications with GRIN1 and Umbilical Cord