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Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 12b (PPP1R12B) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS710084

MBS710084 is an antibody targeting PPP1R12B. Also known as Rabbit anti-human protein phosphatase 1, regulatory (inhibitor) subunit 12B polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$590 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
protein phosphatase 1, regulatory (inhibitor) subunit 12B (PPP1R12B), Polyclonal Antibody
Full Product Name
Rabbit anti-human protein phosphatase 1, regulatory (inhibitor) subunit 12B polyclonal Antibody
Product Gene Name
Product Synonym Names
protein phosphatase 1; regulatory (inhibitor) subunit 12B; PPP1R12B; MGC131980; MGC87886; MYPT2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Molecular Weight
57,501 Da
OMIM
603768
Immunogen
Human PPP1R12B
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PPP1R12B antibody
ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-PPP1R12B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PPP1R12B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein phosphatase 1 regulatory subunit 12B isoform a
NCBI Official Synonym Full Names
protein phosphatase 1, regulatory subunit 12B
NCBI Official Symbol
PPP1R12B
NCBI Official Synonym Symbols
MYPT2; PP1bp55
UniProt Protein Name
Protein phosphatase 1 regulatory subunit 12B
UniProt Synonym Protein Names
Myosin phosphatase-targeting subunit 2; Myosin phosphatase target subunit 2
UniProt Gene Name
PPP1R12B
UniProt Synonym Gene Names
MYPT2; Myosin phosphatase target subunit 2
UniProt Entry Name
MYPT2_HUMAN
NCBI Protein Information
protein phosphatase 1 regulatory subunit 12B; myosin phosphatase target subunit 2; myosin phosphatase, target subunit 2; myosin phosphatase-targeting subunit 2; protein phosphatase 1, regulatory (inhibitor) subunit 12B

NCBI Summary for PPP1R12B

Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome. [provided by RefSeq, Oct 2011]
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UniProt Comments for PPP1R12B

PPP1R12B: Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus. 5 isoforms of the human protein are produced by alternative promoter.

Protein type: Protein phosphatase, regulatory subunit; Activator; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: nucleoplasm; cytoplasm

Molecular Function: enzyme activator activity

Biological Process: positive regulation of catalytic activity; regulation of muscle contraction; mitotic cell cycle; signal transduction; G2/M transition of mitotic cell cycle
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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