GALNT7 Antibody – Rabbit Polyclonal

GALNT7: a glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide. A single-pass type II membrane protein that localizes to the Golgi apparatus membrane. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties.

Protein type: Membrane protein, integral; EC 2.4.1.-; Transferase; Glycan Metabolism - O-glycan biosynthesis

Cellular Component: Golgi apparatus; membrane; integral to membrane

Molecular Function: acetylgalactosaminyltransferase activity; oligosaccharyl transferase activity; alpha(1,6)-fucosyltransferase activity; metal ion binding; alpha(1,3)-fucosyltransferase activity; glucosyltransferase activity; O antigen polymerase activity; alpha-1,2-mannosyltransferase activity; acetylglucosaminyltransferase activity; transferase activity, transferring glycosyl groups; 1-phenanthrol glycosyltransferase activity; phenanthrol glycosyltransferase activity; polypeptide N-acetylgalactosaminyltransferase activity; glycolipid mannosyltransferase activity; carbohydrate binding; galactosyltransferase activity; dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity; fucosyltransferase activity; dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity; lipopolysaccharide-1,6-galactosyltransferase activity; alpha-1,3-galactosyltransferase activity; alpha-1,2-galactosyltransferase activity; 9-phenanthrol UDP-glucuronosyltransferase activity; dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity; UDP-glucose:glycoprotein glucosyltransferase activity; 1,2-dihydroxy-phenanthrene glycosyltransferase activity; transferase activity; 9-phenanthrol glycosyltransferase activity; dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity; beta-1,4-mannosyltransferase activity; cellulose synthase activity; mannosyltransferase activity; alpha-1,3-mannosyltransferase activity; alpha-1,6-mannosyltransferase activity; inositol phosphoceramide synthase activity

Biological Process: protein amino acid O-linked glycosylation