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AGPAT6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS710320

MBS710320 is an antibody targeting AGPAT6. Also known as Rabbit anti-human 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta) polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$590 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta) (AGPAT6), Polyclonal Antibody
Full Product Name
Rabbit anti-human 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta) polyclonal Antibody
Product Gene Name
anti-AGPAT6 antibody
Product Synonym Names
1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase; zeta); AGPAT6; DKFZp586M1819; LPAAT-zeta; LPAATZ; TSARG7
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Molecular Weight
52,071 Da
OMIM
608143
Immunogen
Human AGPAT6
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-AGPAT6 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Other Notes

Small volumes of anti-AGPAT6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AGPAT6. It may not necessarily be applicable to this product.

NCBI GI #
38303981
NCBI GeneID
137964
NCBI Accession #
AAH61884.1
UniProt Secondary Accession #
Q86V89
UniProt Related Accession #
Q86UL3
NCBI Official Full Name
1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)
NCBI Official Synonym Full Names
1-acylglycerol-3-phosphate O-acyltransferase 6
NCBI Official Symbol
AGPAT6
NCBI Official Synonym Symbols
LPAATZ; TSARG7; 1-AGPAT 6; LPAAT-zeta
UniProt Protein Name
Glycerol-3-phosphate acyltransferase 4
UniProt Synonym Protein Names
1-acylglycerol-3-phosphate O-acyltransferase 6; 1-AGP acyltransferase 6; 1-AGPAT 6; Acyl-CoA:glycerol-3-phosphate acyltransferase 4; Lysophosphatidic acid acyltransferase zeta; LPAAT-zeta
UniProt Gene Name
AGPAT6
UniProt Synonym Gene Names
GPAT4; GPAT4; 1-AGP acyltransferase 6; 1-AGPAT 6; LPAAT-zeta
UniProt Entry Name
GPAT4_HUMAN
NCBI Protein Information
glycerol-3-phosphate acyltransferase 6; 1-AGP acyltransferase 6; lysophosphatidic acid acyltransferase zeta; testis spermatogenesis apoptosis-related protein 7; 1-acyl-sn-glycerol-3-phosphate acyltransferase zeta; 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)

NCBI Summary for AGPAT6

Lysophosphatidic acid acyltransferases (EC 2.3.1.51) catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA). LPA and PA are involved in signal transduction and lipid biosynthesis.[supplied by OMIM, Apr 2004]

UniProt Comments for AGPAT6

AGPAT6: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Active against both saturated and unsaturated long- chain fatty acyl-CoAs. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

Protein type: Membrane protein, integral; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - ether lipid; Endoplasmic reticulum; Membrane protein, multi-pass; Transferase; Lipid Metabolism - glycerolipid; EC 2.3.1.15

Chromosomal Location of Human Ortholog: 8p11.21

Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane

Molecular Function: glycerol-3-phosphate O-acyltransferase activity; 1-acylglycerol-3-phosphate O-acyltransferase activity

Biological Process: lactation; acyl-CoA metabolic process; glycerophospholipid biosynthetic process; lipid biosynthetic process; glandular epithelial cell maturation; regulation of multicellular organism growth; triacylglycerol biosynthetic process; cellular lipid metabolic process; fatty acid metabolic process; phospholipid metabolic process; phosphatidylcholine biosynthetic process; phosphatidic acid biosynthetic process; diacylglycerol metabolic process; CDP-diacylglycerol biosynthetic process
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Research Articles on AGPAT6

1. Results reveal a link between the lipogenic effects of insulin and microsomal GPAT3 and GPAT4, implying their importance in glycerolipid biosynthesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AGPAT6 antibody

 Reference Product  PubMed Publications
 LPIN1 antibody  >4 publications with AGPAT6 and LPIN1
 GPAM antibody  >1 publications with AGPAT6 and GPAM

Pathways associated with anti-AGPAT6 antibody

 Products by Pathway  Pathway Diagram
 CDP-diacylglycerol Biosynthesis I Pathway antibodies  CDP-diacylglycerol Biosynthesis I Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerophospholipid Biosynthesis Pathway antibodies  Glycerophospholipid Biosynthesis Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram

Diseases associated with anti-AGPAT6 antibody

 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >1 publications with AGPAT6 and Fatty Liver

Organs/Tissues associated with anti-AGPAT6 antibody

 Organ/Tissue Name  Pubmed Publications
 Mammary Gland Antibodies  >8 publications with AGPAT6 and Mammary Gland
 Adipose Tissue Antibodies  >7 publications with AGPAT6 and Adipose Tissue
 Liver Antibodies  >4 publications with AGPAT6 and Liver
 Connective Tissue Antibodies  >2 publications with AGPAT6 and Connective Tissue
 Testis Antibodies  >2 publications with AGPAT6 and Testis
 Muscle Antibodies  >2 publications with AGPAT6 and Muscle
 Skin Antibodies  >2 publications with AGPAT6 and Skin
 Kidney Antibodies  >1 publications with AGPAT6 and Kidney
 Embryonic Tissue Antibodies  >1 publications with AGPAT6 and Embryonic Tissue
 Intestine Antibodies  >1 publications with AGPAT6 and Intestine
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