Rabbit Anti-RNPS1 Polyclonal Antibody – Cat# MBS710572

RNA Binding Protein S1, Serine-Rich Domain (RNPS1) Antibody – Rabbit Polyclonal

Name: RNPS1 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS710572
Price: 590 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS710572

MBS710572 is an antibody targeting RNPS1. Also known as Rabbit anti-human RNA binding protein S1, serine-rich domain polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$590 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RNA binding protein S1, serine-rich domain (RNPS1), Polyclonal Antibody

Full Product Name

Rabbit anti-human RNA binding protein S1, serine-rich domain polyclonal Antibody

Product Gene Name

anti-RNPS1 antibody

Product Synonym Names

RNA binding protein S1; serine-rich domain; RNPS1; E5.1; MGC117332

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Antigen Affinity Purified

Molecular Weight

30,354 Da

OMIM

606447

Immunogen

Human RNPS1

Storage Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.

Santa Cruz Alternative

Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-19940

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-RNPS1 antibody

ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-RNPS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RNPS1. It may not necessarily be applicable to this product.

NCBI GI #

80478658

NCBI GeneID

10921

NCBI Accession #

AAI08317.1

UniProt Secondary Accession #

O75308; Q32P25; Q8WY42; Q9NYG3; A8K1P0; B4DDU8; B4DZU7; B7ZA17

UniProt Related Accession #

Q15287

NCBI Official Full Name

RNA binding protein S1, serine-rich domain

NCBI Official Synonym Full Names

RNA binding protein S1, serine-rich domain

NCBI Official Symbol

RNPS1

NCBI Official Synonym Symbols

E5.1

UniProt Protein Name

RNA-binding protein with serine-rich domain 1

UniProt Synonym Protein Names

SR-related protein LDC2

Protein Family

RNA-binding protein with serine-rich domain

UniProt Gene Name

RNPS1

UniProt Synonym Gene Names

LDC2

UniProt Entry Name

RNPS1_HUMAN

NCBI Protein Information

RNA-binding protein with serine-rich domain 1; SR protein; SR-related protein LDC2; RNA-binding protein S1, serine-rich domain

NCBI Summary for RNPS1

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

UniProt Comments for RNPS1

RNPS1: a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues.

Protein type: Spliceosome; RNA-binding; RNA splicing; RNA processing

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: nucleoplasm; cytoplasm; nuclear speck; nucleus; cytosol

Molecular Function: protein binding; mRNA 3'-UTR binding; RNA binding; nucleotide binding

Biological Process: transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; mRNA export from nucleus; negative regulation of nuclear mRNA splicing, via spliceosome; transcription, DNA-dependent; positive regulation of apoptosis; RNA splicing; mRNA catabolic process, nonsense-mediated decay; gene expression; mRNA 3'-end processing; termination of RNA polymerase II transcription; regulation of alternative nuclear mRNA splicing, via spliceosome

Research Articles on RNPS1

1. SRBD1 gene polymorphism is associated with the development of HTG as well as NTG, including late-onset NTG.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-RNPS1 antibody

Products by Pathway	Pathway Diagram
Cleavage Of Growing Transcript In The Termination Region Pathway antibodies	Cleavage Of Growing Transcript In The Termination Region Pathway Diagram
Exon Junction Complex (EJC) Pathway antibodies	Exon Junction Complex (EJC) Pathway Diagram
Exon Junction Complex (EJC) Pathway antibodies	Exon Junction Complex (EJC) Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Nonsense Mediated Decay (NMD) Enhanced By The Exon Junction Complex (EJC) Pathway antibodies	Nonsense Mediated Decay (NMD) Enhanced By The Exon Junction Complex (EJC) Pathway Diagram
Nonsense-Mediated Decay (NMD) Pathway antibodies	Nonsense-Mediated Decay (NMD) Pathway Diagram
Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies	Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
RNA Polymerase II Transcription Pathway antibodies	RNA Polymerase II Transcription Pathway Diagram
RNA Polymerase II Transcription Termination Pathway antibodies	RNA Polymerase II Transcription Termination Pathway Diagram
RNA Transport Pathway antibodies	RNA Transport Pathway Diagram

Diseases associated with anti-RNPS1 antibody

Disease Name	Pubmed Publications
Ovarian Diseases Antibodies	>1 publications with RNPS1 and Ovarian Diseases

Organs/Tissues associated with anti-RNPS1 antibody

Organ/Tissue Name	Pubmed Publications
Ovary Antibodies	>3 publications with RNPS1 and Ovary
Nerve Antibodies	>1 publications with RNPS1 and Nerve
Liver Antibodies	>1 publications with RNPS1 and Liver
Blood Antibodies	>1 publications with RNPS1 and Blood
Bone Antibodies	>1 publications with RNPS1 and Bone
Salivary Gland Antibodies	>1 publications with RNPS1 and Salivary Gland
Eye Antibodies	>1 publications with RNPS1 and Eye