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Zinc Finger, FYVE Domain Containing 16 (ZFYVE16) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS710904

MBS710904 is an antibody targeting ZFYVE16. Also known as Rabbit anti-human zinc finger, FYVE domain containing 16 polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$590 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
zinc finger, FYVE domain containing 16 (ZFYVE16), Polyclonal Antibody
Full Product Name
Rabbit anti-human zinc finger, FYVE domain containing 16 polyclonal Antibody
Product Gene Name
Product Synonym Names
zinc finger; FYVE domain containing 16; ZFYVE16; DKFZp686E13162; ENDOFIN; KIAA0305
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Molecular Weight
88,377 Da
OMIM
608880
Immunogen
Human ZFYVE16
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ZFYVE16 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-ZFYVE16 antibody
Recommended Dilution Ratio:
WB : 1:500-1:5000
IHC : 1:20-1:200

Western Blot of anti-ZFYVE16 antibody

MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with ZFYVE16 antibody at dilution of 1:400
Rabbit Anti-ZFYVE16 Polyclonal Antibody – Cat# MBS710904

Western Blot of anti-ZFYVE16 antibody

Mouse kidney tissue were subjected to SDS PAGE followed by western blot with ZFYVE16 antibody at dilution of 1:500
Rabbit Anti-ZFYVE16 Polyclonal Antibody, Western Blot – Cat# MBS710904

Western Blot of anti-ZFYVE16 antibody

HeLa cells were subjected to SDS PAGE followed by western blot with ZFYVE16 antibody at dilution of 1:500
Rabbit Anti-ZFYVE16 Polyclonal Antibody, Western Blot – Cat# MBS710904

Immunohistochemistry of anti-ZFYVE16 antibody

Immunohistochemical of paraffin-embedded human kidney using ZFYVE16 antibody at dilution of 1:100 (under 40x lens)
Rabbit Anti-ZFYVE16 Polyclonal Antibody, Immunohistochemistry – Cat# MBS710904

Immunohistochemistry of anti-ZFYVE16 antibody

Immunohistochemical of paraffin-embedded human kidney using ZFYVE16 antibody at dilution of 1:200 (under 40x lens)
Rabbit Anti-ZFYVE16 Polyclonal Antibody, Immunohistochemistry – Cat# MBS710904

Immunohistochemistry of anti-ZFYVE16 antibody

Immunohistochemical of paraffin-embedded human kidney using ZFYVE16 antibody at dilution of 1:200 (under 10x lens)
Rabbit Anti-ZFYVE16 Polyclonal Antibody, Immunohistochemistry – Cat# MBS710904

Other Notes

Small volumes of anti-ZFYVE16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ZFYVE16. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
zinc finger, FYVE domain containing 16, isoform CRA_a
NCBI Official Synonym Full Names
zinc finger, FYVE domain containing 16
NCBI Official Symbol
ZFYVE16
NCBI Official Synonym Symbols
PPP1R69
UniProt Protein Name
Zinc finger FYVE domain-containing protein 16
UniProt Synonym Protein Names
Endofin; Endosome-associated FYVE domain protein
UniProt Gene Name
ZFYVE16
UniProt Synonym Gene Names
KIAA0305
UniProt Entry Name
ZFY16_HUMAN
NCBI Protein Information
zinc finger FYVE domain-containing protein 16; endosome-associated FYVE-domain protein; protein phosphatase 1, regulatory subunit 69

NCBI Summary for ZFYVE16

This gene encodes an endosomal protein that belongs to the FYVE zinc finger family of proteins. The encoded protein is thought to regulate membrane trafficking in the endosome. This protein functions as a scaffold protein in the transforming growth factor-beta signaling pathway and is involved in positive and negative feedback regulation of the bone morphogenetic protein signaling pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
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UniProt Comments for ZFYVE16

endofin: May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 5q14

Cellular Component: intracellular membrane-bound organelle; early endosome membrane; early endosome; cytoplasm

Molecular Function: protein binding; phosphatidylinositol-3,4,5-triphosphate binding; metal ion binding; protein transporter activity; phosphatidylinositol binding

Biological Process: BMP signaling pathway; protein targeting to lysosome; vesicle organization and biogenesis; regulation of endocytosis; signal transduction; endosome transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-ZFYVE16 antibody

 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >3 publications with ZFYVE16 and Fibrosis
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