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Splicing Factor 3a, Subunit 2 (SF3A2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS711560

MBS711560 is an antibody targeting SF3A2. Also known as Rabbit anti-human splicing factor 3a, subunit 2, 66kDa polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$590 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
splicing factor 3a, subunit 2 (SF3A2), Polyclonal Antibody
Full Product Name
Rabbit anti-human splicing factor 3a, subunit 2, 66kDa polyclonal Antibody
Product Gene Name
Product Synonym Names
splicing factor 3a; subunit 2; 66kDa; SF3A2; PRP11; PRPF11; SAP62; SF3a66
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Molecular Weight
49,256 Da
OMIM
600796
Immunogen
Human SF3A2
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-68790 / sc-68793
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SF3A2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Other Notes

Small volumes of anti-SF3A2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SF3A2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
splicing factor 3A subunit 2
NCBI Official Synonym Full Names
splicing factor 3a, subunit 2, 66kDa
NCBI Official Symbol
SF3A2
NCBI Official Synonym Symbols
PRP11; SAP62; PRPF11; SF3a66
UniProt Protein Name
Splicing factor 3A subunit 2
UniProt Synonym Protein Names
SF3a66; Spliceosome-associated protein 62; SAP 62
Protein Family
UniProt Gene Name
SF3A2
UniProt Synonym Gene Names
SAP62; SAP 62
UniProt Entry Name
SF3A2_HUMAN
NCBI Protein Information
splicing factor 3A subunit 2; SAP 62; spliceosome associated protein 62; spliceosome-associated protein 62; splicing factor 3a, subunit 2, 66kD; pre-mRNA splicing factor SF3A, subunit 2

NCBI Summary for SF3A2

This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein. [provided by RefSeq, Jul 2008]
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UniProt Comments for SF3A2

SF3A2: Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs to the SF3A2 family.

Protein type: RNA-binding; RNA splicing; Spliceosome

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: nucleoplasm; small nuclear ribonucleoprotein complex; spliceosome

Molecular Function: protein binding; zinc ion binding

Biological Process: nuclear mRNA 3'-splice site recognition; nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression; mRNA processing
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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