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Resistance to Inhibitors of Cholinesterase 8 Homolog B (RIC8B) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS711950

MBS711950 is an antibody targeting RIC8B. Also known as Rabbit anti-human resistance to inhibitors of cholinesterase 8 homolog B (C. elegans) polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$590 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
resistance to inhibitors of cholinesterase 8 homolog B (RIC8B), Polyclonal Antibody
Full Product Name
Rabbit anti-human resistance to inhibitors of cholinesterase 8 homolog B (C. elegans) polyclonal Antibody
Product Gene Name
anti-RIC8B antibody
Product Synonym Names
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans); RIC8B; FLJ10620; MGC39476; RIC8; hSyn
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Molecular Weight
28,953 Da
OMIM
609147
Immunogen
Human RIC8B
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-109013 / sc-109014
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-RIC8B antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Other Notes

Small volumes of anti-RIC8B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RIC8B. It may not necessarily be applicable to this product.

NCBI GI #
119618193
NCBI GeneID
55188
NCBI Accession #
EAW97787.1
UniProt Secondary Accession #
Q4G103; Q6ZRN4; Q86WD3; A2RTZ0
UniProt Related Accession #
Q9NVN3
NCBI Official Full Name
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans), isoform CRA_b
NCBI Official Synonym Full Names
RIC8 guanine nucleotide exchange factor B
NCBI Official Symbol
RIC8B
NCBI Official Synonym Symbols
RIC8; hSyn
UniProt Protein Name
Synembryn-B
UniProt Synonym Protein Names
Brain synembryn; hSyn; Protein Ric-8B
Protein Family
Synembryn
UniProt Gene Name
RIC8B
UniProt Synonym Gene Names
hSyn
UniProt Entry Name
RIC8B_HUMAN
NCBI Protein Information
synembryn-B; brain synembrin; brain synembryn; resistance to inhibitors of cholinesterase 8 homolog B

UniProt Comments for RIC8B

RIC8B: a guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Able to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction. Interacts with GDP-bound G alpha proteins GNAI1, GNAL, GNAS and GNAQ. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma. Belongs to the synembryn family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: GEFs, misc.; GEFs

Chromosomal Location of Human Ortholog: 12q23.3

Cellular Component: centrosome; cytoplasm; plasma membrane; cell cortex; cytosol

Molecular Function: guanyl-nucleotide exchange factor activity; G-protein alpha-subunit binding; GTPase activator activity

Biological Process: regulation of G-protein coupled receptor protein signaling pathway; positive regulation of GTPase activity
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Research Articles on RIC8B

1. Ric-8B plays a critical and specific role in the control of G alpha(s) protein levels by modulating G alpha(s) ubiquitination and positively regulates G(s) signaling

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RIC8B antibody

 Reference Product  PubMed Publications
 RTP1 antibody  >1 publications with RIC8B and RTP1

Organs/Tissues associated with anti-RIC8B antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with RIC8B and Brain
 Kidney Antibodies  >2 publications with RIC8B and Kidney
 Bone Antibodies  >1 publications with RIC8B and Bone
 Embryonic Tissue Antibodies  >1 publications with RIC8B and Embryonic Tissue
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