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Eukaryotic Translation Initiation Factor 3, Subunit E (EIF3E) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS712301

MBS712301 is an antibody targeting EIF3E. Also known as Rabbit anti-human eukaryotic translation initiation factor 3, subunit E polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$590 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
eukaryotic translation initiation factor 3, subunit E (EIF3E), Polyclonal Antibody
Full Product Name
Rabbit anti-human eukaryotic translation initiation factor 3, subunit E polyclonal Antibody
Product Gene Name
anti-EIF3E antibody
Product Synonym Names
eukaryotic translation initiation factor 3; subunit E; EIF3E; EIF3-P48; EIF3S6; INT6; eIF3-p46
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Molecular Weight
52,221 Da
OMIM
602210
Immunogen
Human EIF3E
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-16370 / sc-31746 / sc-28859
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-EIF3E antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Other Notes

Small volumes of anti-EIF3E antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EIF3E. It may not necessarily be applicable to this product.

NCBI GI #
4503521
NCBI GeneID
3646
NCBI Accession #
NP_001559.1
UniProt Secondary Accession #
O43902; Q64058; Q64059; Q64252; Q6FG33; Q8WVK4
UniProt Related Accession #
P60228
GenBank Nucleotide #
NM_001568.2
NCBI Official Full Name
eukaryotic translation initiation factor 3 subunit E
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 3, subunit E
NCBI Official Symbol
EIF3E
NCBI Official Synonym Symbols
INT6; EIF3S6; EIF3-P48; eIF3-p46
UniProt Protein Name
Eukaryotic translation initiation factor 3 subunit E
UniProt Synonym Protein Names
Eukaryotic translation initiation factor 3 subunit 6; Viral integration site protein INT-6 homologeIF-3 p48
Protein Family
Eukaryotic translation initiation factor
UniProt Gene Name
EIF3E
UniProt Synonym Gene Names
eIF3e
UniProt Entry Name
EIF3E_HUMAN
NCBI Protein Information
eukaryotic translation initiation factor 3 subunit E; EIF3E; eIF-3 p48; mammary tumor-associated protein INT6; viral integration site protein INT-6 homolog; eukaryotic translation initiation factor 3 subunit 6; murine mammary tumor integration site 6 (oncogene homolog); eukaryotic translation initiation factor 3, subunit 6 48kDa

UniProt Comments for EIF3E

EIF3E: eukaryotic translation initiation factor 3 subunit 2. Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA. eIF-3 is composed of at least 12 different subunits. Phosphorylated by TGF-beta type II receptor.

Protein type: Translation; Translation initiation

Chromosomal Location of Human Ortholog: 8q22-q23

Cellular Component: nucleoplasm; eukaryotic translation initiation factor 3 complex; PML body; membrane; cytoplasm; nucleus; cytosol; chromatin

Molecular Function: protein binding; translation initiation factor activity; protein N-terminus binding

Biological Process: negative regulation of translational initiation; cellular protein metabolic process; translation; mRNA catabolic process, nonsense-mediated decay; translational initiation; gene expression; formation of translation preinitiation complex; regulation of translational initiation
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Research Articles on EIF3E

1. 40S ribosome loading imparts a phosphorylation mark on the cap-binding eIF4F complex that regulates selective mRNA translation and is synchronized by a specific eIF3 subunit

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EIF3E antibody

 Reference Product  PubMed Publications
 EIF3A antibody  >67 publications with EIF3E and EIF3A
 EIF3I antibody  >33 publications with EIF3E and EIF3I
 EIF3B antibody  >28 publications with EIF3E and EIF3B
 EIF3F antibody  >25 publications with EIF3E and EIF3F
 EIF3H antibody  >25 publications with EIF3E and EIF3H
 EIF3C antibody  >23 publications with EIF3E and EIF3C
 EIF3M antibody  >10 publications with EIF3E and EIF3M
 EIF3L antibody  >7 publications with EIF3E and EIF3L
 EIF3D antibody  >6 publications with EIF3E and EIF3D

Pathways associated with anti-EIF3E antibody

 Products by Pathway  Pathway Diagram
 Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway antibodies  Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway Diagram
 Cap-dependent Translation Initiation Pathway antibodies  Cap-dependent Translation Initiation Pathway Diagram
 Eukaryotic Translation Initiation Pathway antibodies  Eukaryotic Translation Initiation Pathway Diagram
 Formation Of A Pool Of Free 40S Subunits Pathway antibodies  Formation Of A Pool Of Free 40S Subunits Pathway Diagram
 Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway antibodies  Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway Diagram
 GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway antibodies  GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 HIF-2-alpha Transcription Factor Network Pathway antibodies  HIF-2-alpha Transcription Factor Network Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram

Diseases associated with anti-EIF3E antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >17 publications with EIF3E and Nervous System Diseases
 Necrosis Antibodies  >11 publications with EIF3E and Necrosis
 Disease Models, Animal Antibodies  >11 publications with EIF3E and Disease Models, Animal
 Liver Neoplasms Antibodies  >9 publications with EIF3E and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >7 publications with EIF3E and Carcinoma, Hepatocellular
 Heart Diseases Antibodies  >6 publications with EIF3E and Heart Diseases
 Hypertrophy Antibodies  >6 publications with EIF3E and Hypertrophy
 Hyperplasia Antibodies  >5 publications with EIF3E and Hyperplasia
 Fibrosis Antibodies  >4 publications with EIF3E and Fibrosis
 Weight Loss Antibodies  >3 publications with EIF3E and Weight Loss

Organs/Tissues associated with anti-EIF3E antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >55 publications with EIF3E and Blood
 Liver Antibodies  >36 publications with EIF3E and Liver
 Muscle Antibodies  >28 publications with EIF3E and Muscle
 Lung Antibodies  >26 publications with EIF3E and Lung
 Brain Antibodies  >16 publications with EIF3E and Brain
 Kidney Antibodies  >13 publications with EIF3E and Kidney
 Prostate Antibodies  >12 publications with EIF3E and Prostate
 Vascular Antibodies  >12 publications with EIF3E and Vascular
 Heart Antibodies  >9 publications with EIF3E and Heart
 Embryonic Tissue Antibodies  >9 publications with EIF3E and Embryonic Tissue
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