• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Mediator Complex Subunit 19 (MED19) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS712340

MBS712340 is an antibody targeting MED19. Also known as Rabbit anti-human mediator complex subunit 19 polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$590 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
mediator complex subunit 19 (MED19), Polyclonal Antibody
Full Product Name
Rabbit anti-human mediator complex subunit 19 polyclonal Antibody
Product Gene Name
anti-MED19 antibody
Product Synonym Names
mediator complex subunit 19; MED19; DT2P1G7; LCMR1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Molecular Weight
20,431 Da
OMIM
612385
Immunogen
Human MED19
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161839 / sc-161840
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MED19 antibody
ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-MED19 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MED19. It may not necessarily be applicable to this product.

NCBI GI #
23273681
NCBI GeneID
219541
NCBI Accession #
AAH37223.1
UniProt Secondary Accession #
Q8IV02; Q8IZD1
UniProt Related Accession #
A0JLT2
NCBI Official Full Name
Mediator complex subunit 19
NCBI Official Synonym Full Names
mediator complex subunit 19
NCBI Official Symbol
MED19
NCBI Official Synonym Symbols
LCMR1; DT2P1G7
UniProt Protein Name
Mediator of RNA polymerase II transcription subunit 19
UniProt Synonym Protein Names
Lung cancer metastasis-related protein 1; Mediator complex subunit 19
Protein Family
Putative mediator of RNA polymerase II transcription
UniProt Gene Name
MED19
UniProt Synonym Gene Names
LCMR1
UniProt Entry Name
MED19_HUMAN
NCBI Protein Information
mediator of RNA polymerase II transcription subunit 19; lung cancer metastasis-related protein 1; mediator of RNA polymerase II transcription, subunit 19 homolog

NCBI Summary for MED19

MED19 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]

UniProt Comments for MED19

MED19: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Belongs to the Mediator complex subunit 19 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 11q12.1

Cellular Component: Srb-mediator complex; nucleus

Molecular Function: protein binding

Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter
Show more

Research Articles on MED19

1. Data show that the expression of Mediator of RNA polymerase II transcription subunit 19 (Med19) was increased in Osteosarcoma (OS) samples from patients compared to normal bone tissues.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MED19 antibody

 Reference Product  PubMed Publications
 MED18 antibody  >2 publications with MED19 and MED18
 MED10 antibody  >2 publications with MED19 and MED10
 MED29 antibody  >1 publications with MED19 and MED29
 MED20 antibody  >1 publications with MED19 and MED20

Pathways associated with anti-MED19 antibody

 Products by Pathway  Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PPARA Activates Gene Expression Pathway antibodies  PPARA Activates Gene Expression Pathway Diagram
 Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies  Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram
 Transcriptional Regulation Of White Adipocyte Differentiation Pathway antibodies  Transcriptional Regulation Of White Adipocyte Differentiation Pathway Diagram

Diseases associated with anti-MED19 antibody

 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >4 publications with MED19 and Lung Diseases
 Death Antibodies  >2 publications with MED19 and Death
 Breast Neoplasms Antibodies  >2 publications with MED19 and Breast Neoplasms
 Carcinoma, Hepatocellular Antibodies  >1 publications with MED19 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with MED19 and Liver Neoplasms

Organs/Tissues associated with anti-MED19 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >5 publications with MED19 and Lung
 Bone Antibodies  >3 publications with MED19 and Bone
 Prostate Antibodies  >2 publications with MED19 and Prostate
 Stomach Antibodies  >1 publications with MED19 and Stomach
 Connective Tissue Antibodies  >1 publications with MED19 and Connective Tissue
 Liver Antibodies  >1 publications with MED19 and Liver
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000