Vesicle Transport Through Interaction with T-Snares Homolog 1b (VTI1B) Antibody – Rabbit Polyclonal

VTI1B: V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. Belongs to the VTI1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle; Membrane protein, integral

Chromosomal Location of Human Ortholog: 14q24.1

Cellular Component: SNARE complex; Golgi apparatus; recycling endosome; synaptic vesicle; endoplasmic reticulum membrane; cell soma; intracellular membrane-bound organelle; perinuclear region of cytoplasm; late endosome membrane; lysosomal membrane; cytoplasm; integral to membrane; vesicle

Molecular Function: SNAP receptor activity; SNARE binding; chloride channel inhibitor activity

Biological Process: vesicle-mediated transport; intra-Golgi vesicle-mediated transport; cell proliferation; ER to Golgi vesicle-mediated transport; autophagic vacuole fusion; Golgi to vacuole transport; vesicle fusion with Golgi apparatus; protein targeting to vacuole; retrograde transport, endosome to Golgi; vesicle docking during exocytosis