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Proline-Serine-Threonine Phosphatase Interacting Protein 1 (PSTPIP1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS712624

MBS712624 is an antibody targeting PSTPIP1. Also known as Rabbit anti-human proline-serine-threonine phosphatase interacting protein 1 polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$590 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
proline-serine-threonine phosphatase interacting protein 1 (PSTPIP1), Polyclonal Antibody
Full Product Name
Rabbit anti-human proline-serine-threonine phosphatase interacting protein 1 polyclonal Antibody
Product Gene Name
Product Synonym Names
proline-serine-threonine phosphatase interacting protein 1; PSTPIP1; CD2BP1; CD2BP1L; CD2BP1S; H-PIP; PAPAS; PSTPIP
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Molecular Weight
45,354 Da
OMIM
606347
Immunogen
Human PSTPIP1
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-104630 / sc-104631
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PSTPIP1 antibody
ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-PSTPIP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PSTPIP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
proline-serine-threonine phosphatase-interacting protein 1
NCBI Official Synonym Full Names
proline-serine-threonine phosphatase interacting protein 1
NCBI Official Symbol
PSTPIP1
NCBI Official Synonym Symbols
H-PIP; PAPAS; CD2BP1; PSTPIP; CD2BP1L; CD2BP1S
UniProt Protein Name
Proline-serine-threonine phosphatase-interacting protein 1
UniProt Synonym Protein Names
CD2-binding protein 1; H-PIP
UniProt Gene Name
PSTPIP1
UniProt Synonym Gene Names
CD2BP1; PEST phosphatase-interacting protein 1
UniProt Entry Name
PPIP1_HUMAN
NCBI Protein Information
proline-serine-threonine phosphatase-interacting protein 1; CD2-binding protein 1; CD2 antigen-binding protein 1; CD2 cytoplasmic tail-binding protein; PEST phosphatase-interacting protein 1

NCBI Summary for PSTPIP1

The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. [provided by RefSeq, Jul 2008]
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UniProt Comments for PSTPIP1

PSTPIP1: an SH3-domain containing protein that may play a role in vesicle formation and transport. Interacts with PTP-PEST to inhibit WASp-driven actin polymerization and synapse formation.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 15q24.3

Cellular Component: membrane; lamellipodium; perinuclear region of cytoplasm; contractile ring; stress fiber; uropod; cytosol; cleavage furrow

Molecular Function: protein binding; actin binding; protein phosphatase binding

Biological Process: innate immune response; endocytosis; signal transduction; inflammatory response; cell adhesion

Disease: Pyogenic Sterile Arthritis, Pyoderma Gangrenosum, And Acne
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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