Caprin Family Member 2 (CAPRIN2) Antibody – Rabbit Polyclonal

The protein encoded by this gene may be involved in the transitioning of erythroblasts from a highly proliferative state to a terminal phase of differentiation. High level expression of the encoded protein can lead to apoptosis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

C1QDC1: May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons. Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation. May be involved in apoptosis. Belongs to the caprin family. 9 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 12p11

Cellular Component: nucleoplasm; centrosome; mitochondrion; cytoplasm; nucleus; receptor complex

Molecular Function: protein binding; RNA binding; receptor binding

Biological Process: positive regulation of protein binding; negative regulation of translation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of dendrite morphogenesis; negative regulation of cell growth; positive regulation of peptidyl-serine phosphorylation