• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Drebrin-Like (DBNL) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS712728

MBS712728 is an antibody targeting DBNL. Also known as Rabbit anti-human drebrin-like polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$590 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
drebrin-like (DBNL), Polyclonal Antibody
Full Product Name
Rabbit anti-human drebrin-like polyclonal Antibody
Product Gene Name
anti-DBNL antibody
Product Synonym Names
drebrin-like; DBNL; ABP1; HIP-55; SH3P7
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Molecular Weight
37,101 Da
OMIM
610106
Immunogen
Human DBNL
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-79973 / sc-79975
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-DBNL antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Other Notes

Small volumes of anti-DBNL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DBNL. It may not necessarily be applicable to this product.

NCBI GI #
21619483
NCBI GeneID
28988
NCBI Accession #
AAH31687.1
UniProt Secondary Accession #
P84070; Q6IAI8; Q96F30; Q96K74; Q9HBN8; Q9NR72; A4D2I9; B4DEM2; C9J7P1
UniProt Related Accession #
Q9UJU6
NCBI Official Full Name
Drebrin-like
NCBI Official Synonym Full Names
drebrin-like
NCBI Official Symbol
DBNL
NCBI Official Synonym Symbols
ABP1; HIP55; SH3P7; HIP-55
UniProt Protein Name
Drebrin-like protein
UniProt Synonym Protein Names
Cervical SH3P7; Cervical mucin-associated protein; Drebrin-F; HPK1-interacting protein of 55 kDa; HIP-55; SH3 domain-containing protein 7
Protein Family
Drebrin-like protein
UniProt Gene Name
DBNL
UniProt Synonym Gene Names
CMAP; SH3P7; HIP-55
UniProt Entry Name
DBNL_HUMAN
NCBI Protein Information
drebrin-like protein; drebrin-F; cervical SH3P7; SH3 domain-containing protein 7; cervical mucin-associated protein; HPK1-interacting protein of 55 kDa; src homology 3 domain-containing protein HIP-55

UniProt Comments for DBNL

DBNL: an SH3-containing adaptor protein. Interacts with hematopoietic progenitor kinase 1a (HIPK1). It is recruited to glycolipid-enriched microdomains following T cell receptor (TCR) stimulation. Interacts with and is phosphorylated by ZAP-70 after TCR signaling. May regulate JNK activation following TCR signaling, presumably via its interaction with HIPKIt is a member of the drebrin family of proteins that are developmentally regulated in the brain.

Protein type: Actin-binding; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 7p13

Cellular Component: Golgi membrane; ruffle; lamellipodium; dendrite; postsynaptic density; cytoplasm; plasma membrane; clathrin coated vesicle membrane; podosome; cell cortex; cytosol; cell junction

Molecular Function: protein C-terminus binding; actin filament binding; protein domain specific binding; protein binding; enzyme activator activity; actin binding

Biological Process: receptor-mediated endocytosis; synaptogenesis; apoptosis; immune system process; Rac protein signal transduction; activation of JNK activity; neurite morphogenesis; cell structure disassembly during apoptosis
Show more

Research Articles on DBNL

1. mAbp1 is of fundamental importance for spreading and migration under shear stress conditions, which are critical prerequisites for efficient PMN extravasation during inflammation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-DBNL antibody

 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptotic Cleavage Of Cellular Proteins Pathway antibodies  Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram
 Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway antibodies  Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway Diagram
 JNK Signaling In The CD4+ TCR Pathway antibodies  JNK Signaling In The CD4+ TCR Pathway Diagram
 TCR Signaling Pathway antibodies  TCR Signaling Pathway Diagram
 TCR Signaling In Naive CD4+ T Cells Pathway antibodies  TCR Signaling In Naive CD4+ T Cells Pathway Diagram

Diseases associated with anti-DBNL antibody

 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >1 publications with DBNL and Lung Neoplasms
 Nervous System Diseases Antibodies  >1 publications with DBNL and Nervous System Diseases
 Lymphoma Antibodies  >1 publications with DBNL and Lymphoma
 Cardiovascular Diseases Antibodies  >1 publications with DBNL and Cardiovascular Diseases
 Breast Neoplasms Antibodies  >1 publications with DBNL and Breast Neoplasms
 Hypertension Antibodies  >1 publications with DBNL and Hypertension
 Necrosis Antibodies  >1 publications with DBNL and Necrosis
 Disease Models, Animal Antibodies  >1 publications with DBNL and Disease Models, Animal
 Inflammation Antibodies  >1 publications with DBNL and Inflammation

Organs/Tissues associated with anti-DBNL antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with DBNL and Brain
 Muscle Antibodies  >5 publications with DBNL and Muscle
 Blood Antibodies  >4 publications with DBNL and Blood
 Lung Antibodies  >3 publications with DBNL and Lung
 Vascular Antibodies  >2 publications with DBNL and Vascular
 Spleen Antibodies  >2 publications with DBNL and Spleen
 Heart Antibodies  >2 publications with DBNL and Heart
 Pancreas Antibodies  >1 publications with DBNL and Pancreas
 Embryonic Tissue Antibodies  >1 publications with DBNL and Embryonic Tissue
 Prostate Antibodies  >1 publications with DBNL and Prostate
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000