B-Cell Receptor-Associated Protein 31 Antibody – Rabbit Polyclonal

BCAP31: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis. Homodimer and heterodimer with BCAP29. Binds CASP8 (isoform 9) as a complex containing BCAP31, BCAP29, BCL2 and/or BCL2L1. Interacts with VAMP3, VAMP1 and membrane IgD immunoglobulins. May interact with ACTG1 and non-muscle myosin II. Interacts with PTPLB. Ubiquitous. Belongs to the BCAP29/BCAP31 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Cellular Component: endoplasmic reticulum membrane; mitochondrion; clathrin-coated vesicle; cell; integral to plasma membrane; endoplasmic reticulum; integral to membrane; lipid particle; cytosol; Golgi membrane; membrane; cytoplasm; plasma membrane; intracellular

Molecular Function: protein binding; MHC class I protein binding; protein complex binding

Biological Process: vesicle-mediated transport; intracellular protein transport; elevation of cytosolic calcium ion concentration; protein transport; ER to Golgi vesicle-mediated transport; apoptosis; transport; reduction of endoplasmic reticulum calcium ion concentration; positive regulation of caspase activity; immune response; elevation of mitochondrial calcium ion concentration