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Placental Growth Factor (PGF) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS713706

Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes… More details

$590 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
placental growth factor (PGF), Polyclonal Antibody
Full Product Name
Rabbit anti-human placental growth factor polyclonal Antibody
Product Gene Name
anti-PGF antibody
Product Synonym Names
placental growth factor; PGF; D12S1900; PGFL; PLGF; PlGF-2; SHGC-10760
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human;Other species are not tested. Please decide the specificity by homology.
Form/Format
Liquid
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
OMIM
601121
Immunogen
Human PGF
Conjugate
Non-conjugated
Storage Buffer
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1880 / sc-27132 / sc-27133 / sc-20714
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PGF antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PGF antibody
ELISA: Use at an assay dependent dilution.
WB : 1:200-1:2000
IP : 1:200-1:2000
IHC : 1:20-1:200 (Recommender dilutions)
Positive WB detected in: MCF7 cells
Positive IP detected in: Human placenta tissue
Positive IHC detected in: Human placenta tissue, human breast cancer tissue, human meningioma tissue

Other Notes

Small volumes of anti-PGF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PGF purchase

MBS713706 is an antibody targeting PGF. Also known as Rabbit anti-human placental growth factor polyclonal Antibody. Reactive in Human;Other species are not tested. Please decide the specificity by homology.. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PGF. It may not necessarily be applicable to this product.

NCBI GI #
14043631
NCBI GeneID
5228
NCBI Accession #
AAH07789.1
UniProt Secondary Accession #
Q07101; Q9BV78; Q9Y6S8
UniProt Related Accession #
P49763
NCBI Official Full Name
Placental growth factor
NCBI Official Synonym Full Names
placental growth factor
NCBI Official Symbol
PGF
NCBI Official Synonym Symbols
PGFL; PLGF; PlGF-2; D12S1900; SHGC-10760
UniProt Protein Name
Placenta growth factor
Protein Family
Placenta growth factor
UniProt Gene Name
PGF
UniProt Synonym Gene Names
PGFL; PLGF; PlGF
UniProt Entry Name
PLGF_HUMAN
NCBI Protein Information
placenta growth factor; placental growth factor, vascular endothelial growth factor-related protein

NCBI Summary for PGF

This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]

UniProt Comments for PGF

PGF: Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. Belongs to the PDGF/VEGF growth factor family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: extracellular space; membrane; extracellular region

Molecular Function: heparin binding; protein binding; protein homodimerization activity; growth factor activity; protein heterodimerization activity

Biological Process: response to drug; positive regulation of angiogenesis; organ regeneration; cell-cell signaling; ureteric bud branching; positive regulation of cell division; positive regulation of cell proliferation; response to hypoxia; positive regulation of endothelial cell proliferation; female pregnancy; sprouting angiogenesis; signal transduction; cell differentiation; vascular endothelial growth factor receptor signaling pathway; cellular response to hormone stimulus
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Research Articles on PGF

1. Healthy women have lower serum and placental levels of PlGF compared to overt diabetics or women with gestational diabetes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PGF antibody

 Reference Product  PubMed Publications
 VEGFA antibody  >24 publications with PGF and VEGFA
 FLT1 antibody  >19 publications with PGF and FLT1
 KDR antibody  >12 publications with PGF and KDR
 EDN1 antibody  >5 publications with PGF and EDN1
 FLT4 antibody  >3 publications with PGF and FLT4
 NRP1 antibody  >3 publications with PGF and NRP1
 AKT1 antibody  >2 publications with PGF and AKT1
 PIK3CA antibody  >1 publications with PGF and PIK3CA

Pathways associated with anti-PGF antibody

 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
 Ras Signaling Pathway antibodies  Ras Signaling Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram

Diseases associated with anti-PGF antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >383 publications with PGF and Cardiovascular Diseases
 Inflammation Antibodies  >284 publications with PGF and Inflammation
 Hypertension Antibodies  >194 publications with PGF and Hypertension
 Disease Models, Animal Antibodies  >159 publications with PGF and Disease Models, Animal
 Necrosis Antibodies  >154 publications with PGF and Necrosis
 Lung Diseases Antibodies  >128 publications with PGF and Lung Diseases
 Heart Diseases Antibodies  >127 publications with PGF and Heart Diseases
 Atherosclerosis Antibodies  >93 publications with PGF and Atherosclerosis
 Brain Diseases Antibodies  >72 publications with PGF and Brain Diseases
 Kidney Diseases Antibodies  >69 publications with PGF and Kidney Diseases

Organs/Tissues associated with anti-PGF antibody

 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >766 publications with PGF and Ovary
 Uterus Antibodies  >732 publications with PGF and Uterus
 Muscle Antibodies  >506 publications with PGF and Muscle
 Heart Antibodies  >251 publications with PGF and Heart
 Lung Antibodies  >238 publications with PGF and Lung
 Kidney Antibodies  >212 publications with PGF and Kidney
 Placenta Antibodies  >208 publications with PGF and Placenta
 Embryonic Tissue Antibodies  >198 publications with PGF and Embryonic Tissue
 Brain Antibodies  >195 publications with PGF and Brain
 Liver Antibodies  >134 publications with PGF and Liver
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