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Intraflagellar Transport 88 Homolog (IFT88) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS713845

MBS713845 is an antibody targeting IFT88. Also known as Rabbit anti-human intraflagellar transport 88 homolog (Chlamydomonas) polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$590 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
intraflagellar transport 88 homolog (IFT88), Polyclonal Antibody
Full Product Name
Rabbit anti-human intraflagellar transport 88 homolog (Chlamydomonas) polyclonal Antibody
Product Gene Name
anti-IFT88 antibody
Product Synonym Names
intraflagellar transport 88 homolog (Chlamydomonas); IFT88; D13S1056E; DAF19; MGC26259; RP11-172H24.2; TG737; TTC10; hTg737
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Molecular Weight
92,381 Da
OMIM
600595
Immunogen
Human IFT88
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-84318
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-IFT88 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Other Notes

Small volumes of anti-IFT88 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IFT88. It may not necessarily be applicable to this product.

NCBI GI #
28558993
NCBI GeneID
8100
NCBI Accession #
NP_783195.2
UniProt Secondary Accession #
Q5SZJ6; Q8N719; A2A491; B4DUS2
UniProt Related Accession #
Q13099
GenBank Nucleotide #
NM_175605.3
NCBI Official Full Name
intraflagellar transport protein 88 homolog isoform 1
NCBI Official Synonym Full Names
intraflagellar transport 88
NCBI Official Symbol
IFT88
NCBI Official Synonym Symbols
DAF19; TG737; TTC10; hTg737; D13S1056E
UniProt Protein Name
Intraflagellar transport protein 88 homolog
UniProt Synonym Protein Names
Recessive polycystic kidney disease protein Tg737 homolog; Tetratricopeptide repeat protein 10; TPR repeat protein 10
Protein Family
Intraflagellar transport protein
UniProt Gene Name
IFT88
UniProt Synonym Gene Names
TG737; TTC10; TPR repeat protein 10
UniProt Entry Name
IFT88_HUMAN
NCBI Protein Information
intraflagellar transport protein 88 homolog; polaris homolog; TPR repeat protein 10; tetratricopeptide repeat domain 10; intraflagellar transport 88 homolog; tetratricopeptide repeat protein 10; recessive polycystic kidney disease protein Tg737 homolog; probe hTg737 (polycystic kidney disease, autosomal recessive)

NCBI Summary for IFT88

This gene encodes a member of the tetratrico peptide repeat (TPR) family. Mutations of a similar gene in mouse can cause polycystic kidney disease. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for IFT88

TTC10: Involved in primary cilium biogenesis. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 13q12.1

Cellular Component: centriole; apical part of cell; motile primary cilium; photoreceptor connecting cilium; cilium; acrosomal membrane

Molecular Function: kinesin binding

Biological Process: positive regulation of insulin-like growth factor receptor signaling pathway; epidermis development; regulation of fat cell differentiation; spinal cord dorsal/ventral patterning; palate development; cytoplasmic microtubule organization and biogenesis; cardiac muscle cell differentiation; anterior/posterior pattern formation; spermatid nuclear elongation; protein localization; pancreas development; kidney development; regulation of odontogenesis of dentine-containing teeth; negative regulation of epithelial cell proliferation; smoothened signaling pathway; Notch signaling pathway; organelle organization and biogenesis; forebrain morphogenesis; liver development; telencephalon development; inner ear receptor stereocilium organization and biogenesis; eye development; sperm axoneme assembly; embryonic digit morphogenesis; determination of left/right symmetry; regulation of smoothened signaling pathway
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Research Articles on IFT88

1. subtle regulation of IFT and associated cilia structure, tunes the wnt response controlling stem cell differentiation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IFT88 antibody

 Reference Product  PubMed Publications
 IFT52 antibody  >10 publications with IFT88 and IFT52
 IFT172 antibody  >9 publications with IFT88 and IFT172
 GLI3 antibody  >6 publications with IFT88 and GLI3
 GLI2 antibody  >5 publications with IFT88 and GLI2
 IFT81 antibody  >4 publications with IFT88 and IFT81
 IFT74 antibody  >2 publications with IFT88 and IFT74

Pathways associated with anti-IFT88 antibody

 Products by Pathway  Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Hedgehog Signaling Events Mediated By Gli Proteins Pathway antibodies  Hedgehog Signaling Events Mediated By Gli Proteins Pathway Diagram

Diseases associated with anti-IFT88 antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >24 publications with IFT88 and Kidney Diseases
 Polycystic Kidney, Autosomal Recessive Antibodies  >11 publications with IFT88 and Polycystic Kidney, Autosomal Recessive
 Brain Diseases Antibodies  >6 publications with IFT88 and Brain Diseases
 Inflammation Antibodies  >4 publications with IFT88 and Inflammation
 Adenocarcinoma Antibodies  >4 publications with IFT88 and Adenocarcinoma
 Liver Diseases Antibodies  >4 publications with IFT88 and Liver Diseases
 Liver Neoplasms Antibodies  >4 publications with IFT88 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >3 publications with IFT88 and Carcinoma, Hepatocellular
 Hyperplasia Antibodies  >3 publications with IFT88 and Hyperplasia
 Polydactyly Antibodies  >3 publications with IFT88 and Polydactyly

Organs/Tissues associated with anti-IFT88 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >36 publications with IFT88 and Kidney
 Eye Antibodies  >14 publications with IFT88 and Eye
 Brain Antibodies  >9 publications with IFT88 and Brain
 Embryonic Tissue Antibodies  >8 publications with IFT88 and Embryonic Tissue
 Liver Antibodies  >7 publications with IFT88 and Liver
 Heart Antibodies  >6 publications with IFT88 and Heart
 Skin Antibodies  >4 publications with IFT88 and Skin
 Blood Antibodies  >4 publications with IFT88 and Blood
 Muscle Antibodies  >4 publications with IFT88 and Muscle
 Testis Antibodies  >3 publications with IFT88 and Testis
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