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Glycine Receptor, Alpha 3 (GLRA3) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS713937

MBS713937 is an antibody targeting GLRA3. Also known as Rabbit anti-human glycine receptor, alpha 3 polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$590 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
glycine receptor, alpha 3 (GLRA3), Polyclonal Antibody
Full Product Name
Rabbit anti-human glycine receptor, alpha 3 polyclonal Antibody
Product Gene Name
anti-GLRA3 antibody
Product Synonym Names
glycine receptor; alpha 3;
Immunogen Sequence
KETDSARSRS APMSPSDFLD KLMGRTSGYD ARIRPNFKGP PVNVTCNIFI NSFGSIAETT MDYRVNIFLR QKWNDPRLAY SEYPDDSLDL DPSMLDSIWK PDLFFANEKG ANFHEVTTDN KLLRIFKNGN VLYSIRLTLT LSCPMDLKNF PMDVQTCIMQ LES FGYTMNDLIF EWQDEAPVQV AEGLTLPQFL LKEEKDLRYC TKHYNTGKFT CIEVRFHLER QMGY
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Upon receipt store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Immunogen Sequence Positions
28-254
OMIM
600421
Immunogen Species
Homo sapiens (Human)
Target Names
GLRA3
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C. Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-17282
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GLRA3 antibody
ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-GLRA3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GLRA3. It may not necessarily be applicable to this product.

NCBI GI #
23241723
NCBI GeneID
8001
NCBI Accession #
AAH36086.1
UniProt Secondary Accession #
O75816; Q5D0E3; D3DP44
UniProt Related Accession #
O75311
NCBI Official Full Name
Glycine receptor, alpha 3
NCBI Official Synonym Full Names
glycine receptor, alpha 3
NCBI Official Symbol
GLRA3
UniProt Protein Name
Glycine receptor subunit alpha-3
Protein Family
Glycine receptor
UniProt Gene Name
GLRA3
UniProt Entry Name
GLRA3_HUMAN
NCBI Protein Information
glycine receptor subunit alpha-3; ligand gated ion channel; glycine receptor, alpha-3 polypeptide

NCBI Summary for GLRA3

This gene encodes a member of the ligand-gated ion channel protein family. The encoded protein is a member of the glycine receptor subfamily. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]

UniProt Comments for GLRA3

GLRA3: The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing). Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA3 sub- subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, ion channel; Membrane protein, integral; Membrane protein, multi-pass; Transporter

Chromosomal Location of Human Ortholog: 4q34.1

Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction

Molecular Function: transmitter-gated ion channel activity; extracellular-glycine-gated chloride channel activity; glycine binding

Biological Process: transmembrane transport
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Research Articles on GLRA3

1. Protein kinase (PK)A-dependent phosphorylation of alpha3 GlyRs produces a conformational change that propagates to the glycine-binding site.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GLRA3 antibody

 Reference Product  PubMed Publications
 GLRA2 antibody  >7 publications with GLRA3 and GLRA2
 GLRA1 antibody  >6 publications with GLRA3 and GLRA1
 GLRB antibody  >4 publications with GLRA3 and GLRB

Pathways associated with anti-GLRA3 antibody

 Products by Pathway  Pathway Diagram
 Ion Channel Transport Pathway antibodies  Ion Channel Transport Pathway Diagram
 Ligand-gated Ion Channel Transport Pathway antibodies  Ligand-gated Ion Channel Transport Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram

Diseases associated with anti-GLRA3 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >5 publications with GLRA3 and Nervous System Diseases
 Pain Antibodies  >3 publications with GLRA3 and Pain
 Central Nervous System Diseases Antibodies  >3 publications with GLRA3 and Central Nervous System Diseases
 Brain Diseases Antibodies  >3 publications with GLRA3 and Brain Diseases
 Neurobehavioral Manifestations Antibodies  >2 publications with GLRA3 and Neurobehavioral Manifestations
 Memory Disorders Antibodies  >1 publications with GLRA3 and Memory Disorders
 Learning Disorders Antibodies  >1 publications with GLRA3 and Learning Disorders
 Inflammation Antibodies  >1 publications with GLRA3 and Inflammation

Organs/Tissues associated with anti-GLRA3 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >10 publications with GLRA3 and Brain
 Blood Antibodies  >1 publications with GLRA3 and Blood
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