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Glyceronephosphate O-Acyltransferase (GNPAT) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS714191

MBS714191 is an antibody targeting GNPAT. Also known as Rabbit anti-human glyceronephosphate O-acyltransferase polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$590 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
glyceronephosphate O-acyltransferase (GNPAT), Polyclonal Antibody
Full Product Name
Rabbit anti-human glyceronephosphate O-acyltransferase polyclonal Antibody
Product Gene Name
anti-GNPAT antibody
Product Synonym Names
glyceronephosphate O-acyltransferase; GNPAT; DAP-AT; DAPAT; DHAPAT
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Molecular Weight
69,906 Da
OMIM
602744
Immunogen
Human GNPAT
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-242920 / sc-242920
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GNPAT antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

Other Notes

Small volumes of anti-GNPAT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GNPAT. It may not necessarily be applicable to this product.

NCBI GI #
12653361
NCBI GeneID
8443
NCBI Accession #
AAH00450.1
UniProt Secondary Accession #
Q5TBH7; Q9BWC2; B4DNM9
UniProt Related Accession #
O15228
NCBI Official Full Name
Glyceronephosphate O-acyltransferase
NCBI Official Synonym Full Names
glyceronephosphate O-acyltransferase
NCBI Official Symbol
GNPAT
NCBI Official Synonym Symbols
DAPAT; DAP-AT; DHAPAT
UniProt Protein Name
Dihydroxyacetone phosphate acyltransferase
UniProt Synonym Protein Names
Acyl-CoA:dihydroxyacetonephosphateacyltransferase; Glycerone-phosphate O-acyltransferase
Protein Family
Dihydroxyacetone phosphate acyltransferase
UniProt Gene Name
GNPAT
UniProt Synonym Gene Names
DAPAT; DHAPAT; DAP-AT; DHAP-AT
UniProt Entry Name
GNPAT_HUMAN
NCBI Protein Information
dihydroxyacetone phosphate acyltransferase; DHAP-AT; glycerone-phosphate O-acyltransferase; acyl-CoA:dihydroxyacetonephosphateacyltransferase

NCBI Summary for GNPAT

This gene encodes an enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in this gene are associated with rhizomelic chondrodysplasia punctata. [provided by RefSeq, Jul 2008]

UniProt Comments for GNPAT

GNPAT: Defects in GNPAT are the cause of rhizomelic chondrodysplasia punctata type 2 (RCDP2). RDCP2 is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation. Belongs to the GPAT/DAPAT family.

Protein type: EC 2.3.1.42; Transferase; Lipid Metabolism - glycerophospholipid

Chromosomal Location of Human Ortholog: 1q42

Cellular Component: peroxisomal membrane; peroxisomal matrix; mitochondrion; membrane; peroxisome

Molecular Function: glycerone-phosphate O-acyltransferase activity; palmitoyl-CoA hydrolase activity; receptor binding

Biological Process: response to drug; response to starvation; synaptogenesis; phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidic acid biosynthetic process; cerebellum morphogenesis; cellular lipid metabolic process; response to nutrient; paranodal junction assembly; ether lipid biosynthetic process

Disease: Rhizomelic Chondrodysplasia Punctata, Type 2
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Research Articles on GNPAT

1. ACOX1 and GNPAT silencing up-regulated ceramide galactosyltransferase (UGT8) mRNA expression, and down-regulated UDP-glucoseceramide glucosyltransferase (UGCG).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GNPAT antibody

 Reference Product  PubMed Publications
 PEX7 antibody  >2 publications with GNPAT and PEX7
 AGPS antibody  >2 publications with GNPAT and AGPS

Pathways associated with anti-GNPAT antibody

 Products by Pathway  Pathway Diagram
 Glycerophospholipid Biosynthesis Pathway antibodies  Glycerophospholipid Biosynthesis Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Peroxisomal Lipid Metabolism Pathway antibodies  Peroxisomal Lipid Metabolism Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Phospholipid Metabolism Pathway antibodies  Phospholipid Metabolism Pathway Diagram
 Plasmalogen Biosynthesis Pathway antibodies  Plasmalogen Biosynthesis Pathway Diagram

Diseases associated with anti-GNPAT antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2 publications with GNPAT and Nervous System Diseases
 Limb Deformities, Congenital Antibodies  >1 publications with GNPAT and Limb Deformities, Congenital
 Kidney Diseases Antibodies  >1 publications with GNPAT and Kidney Diseases
 Abnormalities, Multiple Antibodies  >1 publications with GNPAT and Abnormalities, Multiple
 Fatty Liver Antibodies  >1 publications with GNPAT and Fatty Liver
 Rhizomelic chondrodysplasia punctata, type 2 Antibodies  >1 publications with GNPAT and Rhizomelic chondrodysplasia punctata, type 2

Organs/Tissues associated with anti-GNPAT antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with GNPAT and Blood
 Brain Antibodies  >2 publications with GNPAT and Brain
 Liver Antibodies  >1 publications with GNPAT and Liver
 Thymus Antibodies  >1 publications with GNPAT and Thymus
 Skin Antibodies  >1 publications with GNPAT and Skin
 Kidney Antibodies  >1 publications with GNPAT and Kidney
 Testis Antibodies  >1 publications with GNPAT and Testis
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