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High-Mobility Group Nucleosome Binding Domain 1 (HMGN1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS714425

MBS714425 is an antibody targeting HMGN1. Also known as Rabbit anti-human high-mobility group nucleosome binding domain 1 polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$590 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
high-mobility group nucleosome binding domain 1 (HMGN1), Polyclonal Antibody
Full Product Name
Rabbit anti-human high-mobility group nucleosome binding domain 1 polyclonal Antibody
Product Gene Name
anti-HMGN1 antibody
Product Synonym Names
high-mobility group nucleosome binding domain 1; HMGN1; FLJ27265; FLJ31471; HMG14; MGC104230; MGC117425
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Molecular Weight
10,659 Da
OMIM
163920
Immunogen
Human HMGN1
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-19074 / sc-19075
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-HMGN1 antibody
ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-HMGN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HMGN1. It may not necessarily be applicable to this product.

NCBI GI #
76780221
NCBI GeneID
3150
NCBI Accession #
AAI06081.1
UniProt Secondary Accession #
Q3KQR8
UniProt Related Accession #
P05114
NCBI Official Full Name
High-mobility group nucleosome binding domain 1
NCBI Official Synonym Full Names
high mobility group nucleosome binding domain 1
NCBI Official Symbol
HMGN1
NCBI Official Synonym Symbols
HMG14
UniProt Protein Name
Non-histone chromosomal protein HMG-14
UniProt Synonym Protein Names
High mobility group nucleosome-binding domain-containing protein 1
Protein Family
Non-histone chromosomal protein
UniProt Gene Name
HMGN1
UniProt Synonym Gene Names
HMG14
UniProt Entry Name
HMGN1_HUMAN
NCBI Protein Information
non-histone chromosomal protein HMG-14; nonhistone chromosomal protein HMG-14; high-mobility group nucleosome binding 1; high-mobility group nucleosome binding domain 1; high-mobility group (nonhistone chromosomal) protein 14; high mobility group nucleosome-binding domain-containing protein 1

NCBI Summary for HMGN1

The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes. [provided by RefSeq, Aug 2011]

UniProt Comments for HMGN1

HMGN1: a nonhistone chromosomal protein of the HMG-14/HMG-17 protein family. Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation.

Protein type: Nuclear receptor co-regulator; DNA-binding

Chromosomal Location of Human Ortholog: 21q22.2

Cellular Component: cytoplasm; chromatin; nucleus

Molecular Function: nucleosomal DNA binding; DNA binding

Biological Process: regulation of transcription from RNA polymerase II promoter; establishment and/or maintenance of chromatin architecture; transcription-coupled nucleotide-excision repair; positive regulation of RNA elongation; pyrimidine dimer repair via nucleotide-excision repair; regulation of development, heterochronic; post-embryonic camera-type eye morphogenesis; regulation of epithelial cell proliferation; response to UV-C; response to UV-B
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Research Articles on HMGN1

1. nucleosome binding protein HMGN1 as a new PCNA-interacting protein that enhances the binding of PCNA to chromatin

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HMGN1 antibody

 Reference Product  PubMed Publications
 HMGN2 antibody  >135 publications with HMGN1 and HMGN2
 XAB2 antibody  >3 publications with HMGN1 and XAB2
 MECP2 antibody  >1 publications with HMGN1 and MECP2
 ZNF219 antibody  >1 publications with HMGN1 and ZNF219

Pathways associated with anti-HMGN1 antibody

 Products by Pathway  Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 P38 MAPK Signaling Pathway antibodies  P38 MAPK Signaling Pathway Diagram

Diseases associated with anti-HMGN1 antibody

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >17 publications with HMGN1 and Disease Models, Animal
 Congenital Abnormalities Antibodies  >8 publications with HMGN1 and Congenital Abnormalities
 Carcinoma Antibodies  >8 publications with HMGN1 and Carcinoma
 Cell Transformation, Neoplastic Antibodies  >8 publications with HMGN1 and Cell Transformation, Neoplastic
 Liver Diseases Antibodies  >5 publications with HMGN1 and Liver Diseases
 Liver Neoplasms Antibodies  >5 publications with HMGN1 and Liver Neoplasms
 Liver Neoplasms, Experimental Antibodies  >4 publications with HMGN1 and Liver Neoplasms, Experimental
 Learning Disorders Antibodies  >3 publications with HMGN1 and Learning Disorders
 Memory Disorders Antibodies  >3 publications with HMGN1 and Memory Disorders
 Adenocarcinoma Antibodies  >2 publications with HMGN1 and Adenocarcinoma

Organs/Tissues associated with anti-HMGN1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >54 publications with HMGN1 and Blood
 Thymus Antibodies  >47 publications with HMGN1 and Thymus
 Liver Antibodies  >32 publications with HMGN1 and Liver
 Brain Antibodies  >21 publications with HMGN1 and Brain
 Heart Antibodies  >10 publications with HMGN1 and Heart
 Thyroid Antibodies  >10 publications with HMGN1 and Thyroid
 Testis Antibodies  >9 publications with HMGN1 and Testis
 Muscle Antibodies  >9 publications with HMGN1 and Muscle
 Spleen Antibodies  >9 publications with HMGN1 and Spleen
 Bone Antibodies  >8 publications with HMGN1 and Bone
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