Rac Gtpase Activating Protein 1 (RACGAP1) Antibody – Rabbit Polyclonal

MgcRacGAP: a rac GTPase activating protein. Plays an important role in cytokinesis by regulating cortical movement through RhoA. Phosphorylation by Aurora B apparently induces GAP activity toward RhoA.

Protein type: GAPs, Rac/Rho; GAPs

Cellular Component: nucleoplasm; extrinsic to internal side of plasma membrane; cytoskeleton; membrane; cytoplasm; plasma membrane; intracellular; midbody; cytoplasmic vesicle; spindle midzone; nucleus; cleavage furrow

Molecular Function: gamma-tubulin binding; phosphatidylinositol-3,4,5-triphosphate binding; metal ion binding; microtubule binding; beta-tubulin binding; protein kinase binding; lipid binding; alpha-tubulin binding; GTPase activator activity

Biological Process: positive regulation of cytokinesis; regulation of attachment of spindle microtubules to kinetochore; spindle midzone assembly involved in mitosis; multicellular organismal development; sulfate transport; cell cycle; signal transduction; embryonic development; cytokinesis after mitosis; cell division; transport; spermatogenesis; ion transport; cell differentiation; cytokinesis, contractile ring formation; positive regulation of GTPase activity