• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Membrane-Associated Phosphatidylinositol Transfer Protein 1 (PITPNM1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS715054

Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May… More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Membrane-associated phosphatidylinositol transfer protein 1 (PITPNM1), Polyclonal Antibody
Full Product Name
Rabbit anti- human Membrane-associated phosphatidylinositol transfer protein 1 polyclonal Antibody
Product Gene Name
anti-PITPNM1 antibody
Product Synonym Names
Drosophila retinal degeneration B homolog; Phosphatidylinositol transfer protein; membrane-associated 1; Pyk2 N-terminal domain-interacting receptor 2; DRES9; NIR2; PITPNM
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: PITPNM1 (MBS715054)
Biotin Conjugated Antibody: PITPNM1 (MBS715006)
Matching Pairs
Unconjugated Antibody: PITPNM1 (MBS715054)
HRP Conjugated Antibody: PITPNM1 (MBS715198)
Show more
Molecular Weight
134,777 Da
OMIM
608794
3D Structure
ModBase 3D Structure for O00562
Storage Buffer
PBS
Conjugate
Non-conjugated
Immunogen
Recombinant human Membrane-associated phosphatidylinositol transfer protein 1 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-23662 / sc-23663
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PITPNM1 antibody
ELISA (EIA)

Other Notes

Small volumes of anti-PITPNM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PITPNM1 purchase

MBS715054 is an antibody targeting PITPNM1. Also known as Rabbit anti- human Membrane-associated phosphatidylinositol transfer protein 1 polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PITPNM1. It may not necessarily be applicable to this product.

NCBI GI #
195927017
NCBI GeneID
9600
NCBI Accession #
NP_001124320.1
UniProt Primary Accession #
O00562
UniProt Secondary Accession #
Q6T7X3; Q8TBN3; Q9BZ73; A6NME4
UniProt Related Accession #
O00562
GenBank Nucleotide #
NM_001130848.1
NCBI Official Full Name
membrane-associated phosphatidylinositol transfer protein 1 isoform b
NCBI Official Synonym Full Names
phosphatidylinositol transfer protein, membrane associated 1
NCBI Official Symbol
PITPNM1
NCBI Official Synonym Symbols
Rd9; NIR2; RDGB; DRES9; RDGB1; RDGBA; PITPNM; RDGBA1
UniProt Protein Name
Membrane-associated phosphatidylinositol transfer protein 1
UniProt Synonym Protein Names
Drosophila retinal degeneration B homolog; Phosphatidylinositol transfer protein, membrane-associated 1; PITPnm 1; Pyk2 N-terminal domain-interacting receptor 2; NIR-2
Protein Family
Membrane-associated phosphatidylinositol transfer protein
UniProt Gene Name
PITPNM1
UniProt Synonym Gene Names
DRES9; NIR2; PITPNM; PITPnm 1; NIR-2
UniProt Entry Name
PITM1_HUMAN
NCBI Protein Information
membrane-associated phosphatidylinositol transfer protein 1

NCBI Summary for PITPNM1

PITPNM1 belongs to a family of membrane-associated phosphatidylinositol transfer domain-containing proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein (Ocaka et al., 2005 [PubMed 15627748]).[supplied by OMIM, Mar 2008]

UniProt Comments for PITPNM1

PITPNM1: putatively transfers phosphatidylinositol and phosphatidylcholine between membranes. Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Has higher affinity for the inactive, GDP-bound form of RHOA. Necessary for normal completion of cytokinesis and for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions. Interacts with PIK4CA and with Pyk2 via its C-terminus. Phosphorylated on multiple sites by CDC2 at the onset of mitosis. CDC2-phosphorylated forms may interact with PLK1. Interacts with VAPB. Phosphorylated on threonine residues upon treatment with oleic acid.

Protein type: Cell surface

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: cleavage furrow; cytoplasm; endoplasmic reticulum membrane; lipid particle; membrane; midbody

Molecular Function: metal ion binding; phosphatidylinositol transporter activity; protein binding

Biological Process: brain development; lipid metabolic process; phospholipid transport; phototransduction; protein transport
Show more

Research Articles on PITPNM1

1. results suggest that Nir2 not only enhances EMT in vitro and breast cancer metastasis in animal models, but also contributes to breast cancer progression in human patients.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PITPNM1 antibody

 Reference Product  PubMed Publications
 VAPB antibody  >3 publications with PITPNM1 and VAPB
 RHOA antibody  >2 publications with PITPNM1 and RHOA
 PLK1 antibody  >1 publications with PITPNM1 and PLK1
 PTPRQ antibody  >1 publications with PITPNM1 and PTPRQ
 CDK1 antibody  >1 publications with PITPNM1 and CDK1
 PTK2B antibody  >1 publications with PITPNM1 and PTK2B

Diseases associated with anti-PITPNM1 antibody

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1 publications with PITPNM1 and Breast Neoplasms
 Disease Models, Animal Antibodies  >1 publications with PITPNM1 and Disease Models, Animal

Organs/Tissues associated with anti-PITPNM1 antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >20 publications with PITPNM1 and Eye
 Brain Antibodies  >2 publications with PITPNM1 and Brain
 Lung Antibodies  >1 publications with PITPNM1 and Lung
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000