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Collagen Type 1 (COL-I Ab) ELISA Kit for Horse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS007155

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of COL-I-AB (hereafter termed this analyte) in Horse serum, plasma and tissue homogenate samples. More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Collagen Type I Antibody (COL-I Ab), ELISA Kit
Full Product Name
Horse Collagen Type I Antibody ELISA Kit
Product Gene Name
COL-I Ab elisa kit
Species Reactivity
Horse
Assay Type
Sandwich
Samples
Serum, Plasma and Tissue Homogenate
Detection Range
0.25ng/ml-8ng/ml.
Sensitivity
0.1ng/ml.
Specificity
No significant cross-reactivity or interference between this analyte and analogues is observed.
Preparation and Storage
Store all reagents at 2-8 degree C
Intra-assay Precision
Intra-assay CV (%) is less than 15%.
Molecular Weight
47,328 Da
Chromosome Location
Chromosome: 14; NC_000014.8 (76424442..76448092, complement). Location: 14q24
OMIM
107970
3D Structure
ModBase 3D Structure for P10600
Inter-assay
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Other Notes

Small volumes of COL-I Ab elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for COL-I Ab purchase

MBS007155 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Collagen Type I Antibody (COL-I Ab) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing COL-I Ab. The ELISA analytical biochemical technique of the MBS007155 kit is based on COL-I Ab antibody-COL-I Ab antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect COL-I Ab antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, COL-I Ab. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for COL-I Ab. It may not necessarily be applicable to this product.

NCBI GI #
4507465
NCBI GeneID
7043
NCBI Accession #
NP_003230.1
UniProt Primary Accession #
P10600
UniProt Related Accession #
P10600
GenBank Nucleotide #
NM_003239.2
NCBI Official Full Name
transforming growth factor beta-3 preproprotein
NCBI Official Synonym Full Names
transforming growth factor, beta 3
NCBI Official Symbol
TGFB3
NCBI Official Synonym Symbols
ARVD; TGF-beta3
UniProt Protein Name
Transforming growth factor beta-3
UniProt Gene Name
TGFB3
UniProt Synonym Gene Names
TGF-beta-3; LAP
UniProt Entry Name
TGFB3_HUMAN
NCBI Protein Information
transforming growth factor beta-3; TGF-beta-3

NCBI Summary for COL-I Ab

This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and is involved in embryogenesis and cell differentiation. Defects in this gene are a cause of familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Mar 2009]

UniProt Comments for COL-I Ab

TGFB3: Involved in embryogenesis and cell differentiation. Homodimer; disulfide-linked. Interacts with ASPN. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Ligand, receptor tyrosine kinase; Secreted; Cell development/differentiation; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 14q24

Cellular Component: extracellular matrix; extracellular space; cell surface; cell soma; T-tubule; plasma membrane; extracellular region; nucleus

Molecular Function: identical protein binding; protein binding; growth factor activity; transforming growth factor beta binding; protein heterodimerization activity; punt binding; cytokine activity

Biological Process: extracellular matrix organization and biogenesis; activation of MAPK activity; positive regulation of apoptosis; positive regulation of transcription, DNA-dependent; positive regulation of collagen biosynthetic process; SMAD protein nuclear translocation; palate development; female pregnancy; regulation of apoptosis; odontogenesis; negative regulation of cell proliferation; platelet degranulation; mammary gland development; transforming growth factor beta receptor signaling pathway; salivary gland morphogenesis; embryonic neurocranium morphogenesis; negative regulation of neuron apoptosis; cell growth; inner ear development; aging; positive regulation of filopodium formation; uterine wall breakdown; platelet activation; intercellular junction assembly and maintenance; in utero embryonic development; positive regulation of bone mineralization; regulation of cell proliferation; positive regulation of protein secretion; gut development; response to estrogen stimulus; negative regulation of DNA replication; positive regulation of cell division; regulation of MAPKKK cascade; response to hypoxia; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; blood coagulation; response to progesterone stimulus; alveolus development; positive regulation of DNA replication

Disease: Arrhythmogenic Right Ventricular Dysplasia, Familial, 1; Rienhoff Syndrome
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Research Articles on COL-I Ab

1. These findings suggest human serum, FGF-2 and TGF-beta3 as possible candidates to support biological treatment strategies of AF defects.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with COL-I Ab elisa kit

 Reference Product  PubMed Publications
 TGFB2 elisa kit  >537 publications with COL-I Ab and TGFB2
 EGF elisa kit  >17 publications with COL-I Ab and EGF
 SERPINE1 elisa kit  >13 publications with COL-I Ab and SERPINE1
 TGFBR1 elisa kit  >7 publications with COL-I Ab and TGFBR1
 TGFBR2 elisa kit  >7 publications with COL-I Ab and TGFBR2
 SMAD5 elisa kit  >2 publications with COL-I Ab and SMAD5
 TIMP1 elisa kit  >1 publications with COL-I Ab and TIMP1
 ACVRL1 elisa kit  >1 publications with COL-I Ab and ACVRL1

Pathways associated with COL-I Ab elisa kit

 Products by Pathway  Pathway Diagram
 ALK1 Signaling Events Pathway antibodies  ALK1 Signaling Events Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chronic Myeloid Leukemia Pathway antibodies  Chronic Myeloid Leukemia Pathway Diagram
 Chronic Myeloid Leukemia Pathway antibodies  Chronic Myeloid Leukemia Pathway Diagram
 Colorectal Cancer Pathway antibodies  Colorectal Cancer Pathway Diagram

Diseases associated with COL-I Ab elisa kit

 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >177 publications with COL-I Ab and Fibrosis
 Cleft Palate Antibodies  >91 publications with COL-I Ab and Cleft Palate
 Disease Models, Animal Antibodies  >88 publications with COL-I Ab and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >82 publications with COL-I Ab and Cardiovascular Diseases
 Inflammation Antibodies  >63 publications with COL-I Ab and Inflammation
 Necrosis Antibodies  >57 publications with COL-I Ab and Necrosis
 Heart Diseases Antibodies  >50 publications with COL-I Ab and Heart Diseases
 Breast Neoplasms Antibodies  >35 publications with COL-I Ab and Breast Neoplasms
 Lung Diseases Antibodies  >33 publications with COL-I Ab and Lung Diseases
 Adenocarcinoma Antibodies  >28 publications with COL-I Ab and Adenocarcinoma

Organs/Tissues associated with COL-I Ab elisa kit

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >309 publications with COL-I Ab and Bone
 Connective Tissue Antibodies  >211 publications with COL-I Ab and Connective Tissue
 Embryonic Tissue Antibodies  >130 publications with COL-I Ab and Embryonic Tissue
 Mouth Antibodies  >109 publications with COL-I Ab and Mouth
 Bone Marrow Antibodies  >102 publications with COL-I Ab and Bone Marrow
 Heart Antibodies  >76 publications with COL-I Ab and Heart
 Lung Antibodies  >69 publications with COL-I Ab and Lung
 Brain Antibodies  >63 publications with COL-I Ab and Brain
 Eye Antibodies  >58 publications with COL-I Ab and Eye
 Liver Antibodies  >50 publications with COL-I Ab and Liver
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