• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

WAP Four-Disulfide Core Domain Protein 2 (WFDC2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS715810

MBS715810 is an antibody targeting WFDC2. Also known as Rabbit anti-human WAP four-disulfide core domain protein 2 polyclonal Antibody. Reactive in Human. Host: Rabbit. More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
WAP four-disulfide core domain protein 2 (WFDC2), Polyclonal Antibody
Full Product Name
Rabbit anti-human WAP four-disulfide core domain protein 2 polyclonal Antibody
Product Gene Name
anti-WFDC2 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: WAP four-disulfide core domain protein 2 (MBS715810)
HRP Conjugated Antibody: WAP four-disulfide core domain protein 2 (MBS715633)
Matching Pairs
Unconjugated Antibody: WAP four-disulfide core domain protein 2 (MBS715810)
Biotin Conjugated Antibody: WAP four-disulfide core domain protein 2 (MBS715640)
Show more
Molecular Weight
11,043 Da
3D Structure
ModBase 3D Structure for Q14508
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human WAP four-disulfide core domain protein 2 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-27570
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-WFDC2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Western Blot (WB) of anti-WFDC2 antibody

Western Blot
Positive WB detected in: hepG2 cell,mouse heart
All lanes: WFDC2 antibody at 4ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 13,9,12 kDa
Observed band size: 12 kDa
Rabbit Anti-WFDC2 Polyclonal Antibody – Cat# MBS715810

Immunohistochemistry (IHC) of anti-WFDC2 antibody

Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS715810 at dilution 1:100
Rabbit Anti-WFDC2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS715810

Immunohistochemistry (IHC) of anti-WFDC2 antibody

Immunofluorescent analysis of 293T cells using MBS715810 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Rabbit Anti-WFDC2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS715810

Immunofluorescence (IF) of anti-WFDC2 antibody

Immunofluorescent analysis of MCF-7 cells using MBS715810 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Rabbit Anti-WFDC2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS715810

Other Notes

Small volumes of anti-WFDC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for WFDC2. It may not necessarily be applicable to this product.

NCBI GI #
56699495
NCBI GeneID
10406
NCBI Accession #
NP_006094.3
UniProt Primary Accession #
Q14508
UniProt Secondary Accession #
Q6IB27; Q8WXV9; Q8WXW0; Q8WXW1; Q8WXW2; Q96KJ1; A2A2A5; A2A2A6; A6PVD5
UniProt Related Accession #
Q14508
GenBank Nucleotide #
NM_006103.3
NCBI Official Full Name
WAP four-disulfide core domain protein 2
NCBI Official Synonym Full Names
WAP four-disulfide core domain 2
NCBI Official Symbol
WFDC2
NCBI Official Synonym Symbols
HE4; WAP5; EDDM4; dJ461P17.6
UniProt Protein Name
WAP four-disulfide core domain protein 2
UniProt Synonym Protein Names
Epididymal secretory protein E4; Major epididymis-specific protein E4; Putative protease inhibitor WAP5
Protein Family
WAP four-disulfide core domain protein
UniProt Gene Name
WFDC2
UniProt Synonym Gene Names
HE4; WAP5
UniProt Entry Name
WFDC2_HUMAN
NCBI Protein Information
WAP four-disulfide core domain protein 2

NCBI Summary for WFDC2

This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for WFDC2

WFDC2: a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008]

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 20q13.12

Cellular Component: extracellular space

Molecular Function: aspartic-type endopeptidase inhibitor activity; cysteine protease inhibitor activity; endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity

Biological Process: proteolysis; spermatogenesis
Show more

Research Articles on WFDC2

1. Serum HE4 measured during clinical follow-up may identify recurrent disease particularly in patients with endometrioid histology.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-WFDC2 antibody

 Reference Product  PubMed Publications
 SLPI antibody  >8 publications with WFDC2 and SLPI
 EGFR antibody  >6 publications with WFDC2 and EGFR
 MSLN antibody  >2 publications with WFDC2 and MSLN
 MUC1 antibody  >1 publications with WFDC2 and MUC1

Diseases associated with anti-WFDC2 antibody

 Disease Name  Pubmed Publications
 Ovarian Neoplasms Antibodies  >149 publications with WFDC2 and Ovarian Neoplasms
 Adenocarcinoma Antibodies  >28 publications with WFDC2 and Adenocarcinoma
 Lung Neoplasms Antibodies  >16 publications with WFDC2 and Lung Neoplasms
 Breast Neoplasms Antibodies  >8 publications with WFDC2 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >4 publications with WFDC2 and Neoplasms, Experimental
 Inflammation Antibodies  >3 publications with WFDC2 and Inflammation
 Hyperplasia Antibodies  >3 publications with WFDC2 and Hyperplasia
 Infertility, Female Antibodies  >3 publications with WFDC2 and Infertility, Female
 Fibrosis Antibodies  >2 publications with WFDC2 and Fibrosis
 Prostatic Neoplasms Antibodies  >2 publications with WFDC2 and Prostatic Neoplasms

Organs/Tissues associated with anti-WFDC2 antibody

 Organ/Tissue Name  Pubmed Publications
 Epididymis Antibodies  >107 publications with WFDC2 and Epididymis
 Lung Antibodies  >17 publications with WFDC2 and Lung
 Ovary Antibodies  >17 publications with WFDC2 and Ovary
 Uterus Antibodies  >7 publications with WFDC2 and Uterus
 Kidney Antibodies  >5 publications with WFDC2 and Kidney
 Prostate Antibodies  >4 publications with WFDC2 and Prostate
 Muscle Antibodies  >3 publications with WFDC2 and Muscle
 Trachea Antibodies  >3 publications with WFDC2 and Trachea
 Heart Antibodies  >2 publications with WFDC2 and Heart
 Mammary Gland Antibodies  >2 publications with WFDC2 and Mammary Gland
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000