Phospholipid Scramblase 4 (PLSCR4) Antibody – Rabbit Polyclonal

PLSCR4: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Belongs to the phospholipid scramblase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q24

Cellular Component: plasma membrane; integral to membrane

Molecular Function: phospholipid scramblase activity; protein binding; enzyme binding; calcium ion binding; CD4 receptor binding; SH3 domain binding

Biological Process: phospholipid scrambling