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Tubulin, Beta 2b (TUBB2B) Antibody – Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS716606

MBS716606 is an antibody targeting TUBB2B. Also known as Rabbit anti-human tubulin, beta 2B polyclonal Antibody. Reactive in Human, Mouse, Rat. More details

$590 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
tubulin, beta 2B (TUBB2B), Polyclonal Antibody
Full Product Name
Rabbit anti-human tubulin, beta 2B polyclonal Antibody
Product Gene Name
anti-TUBB2B antibody
Clonality
Polyclonal
Isotype
IgG
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Molecular Weight
49,953 Da
OMIM
612850
Immunogen
Human TUBB2B
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TUBB2B antibody
ELISA (EIA)

Other Notes

Small volumes of anti-TUBB2B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TUBB2B. It may not necessarily be applicable to this product.

NCBI GI #
39645753
NCBI GeneID
347733
NCBI Accession #
AAH63610.1
UniProt Secondary Accession #
A8K068
UniProt Related Accession #
Q9BVA1
NCBI Official Full Name
Tubulin, beta 2B
NCBI Official Synonym Full Names
tubulin, beta 2B class IIb
NCBI Official Symbol
TUBB2B
NCBI Official Synonym Symbols
PMGYSA; bA506K6.1
UniProt Protein Name
Tubulin beta-2B chain
Protein Family
Tubulin
UniProt Gene Name
TUBB2B
UniProt Entry Name
TBB2B_HUMAN
NCBI Protein Information
tubulin beta-2B chain; class IIb beta-tubulin; class II beta-tubulin isotype; tubulin, beta polypeptide paralog

NCBI Summary for TUBB2B

The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a cause of asymmetric polymicrogyria. [provided by RefSeq, Mar 2010]

UniProt Comments for TUBB2B

TUBB2B: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB2B is implicated in neuronal migration. Defects in TUBB2B are a cause of polymicrogyria asymmetric (PMGA). PMGA is a malformation of the cortex in which the brain surface is irregular and characterized by an excessive number of small gyri with abnormal lamination. Belongs to the tubulin family.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 6p25

Cellular Component: microtubule; cytoplasm; nucleus

Molecular Function: GTPase activity; protein binding; GTP binding; structural constituent of cytoskeleton

Biological Process: protein polymerization; 'de novo' posttranslational protein folding; cellular protein metabolic process; protein folding; neuron migration; transmembrane transport; microtubule-based process

Disease: Polymicrogyria, Symmetric Or Asymmetric
Show more

Research Articles on TUBB2B

1. The present study confirms that mutations in tubulin genes are responsible for complex brain malformation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TUBB2B antibody

 Reference Product  PubMed Publications
 TUBA1A antibody  >16 publications with TUBB2B and TUBA1A

Pathways associated with anti-TUBB2B antibody

 Products by Pathway  Pathway Diagram
 Chaperonin-mediated Protein Folding Pathway antibodies  Chaperonin-mediated Protein Folding Pathway Diagram
 Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway antibodies  Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway Diagram
 Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway antibodies  Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Parkin-Ubiquitin Proteasomal System Pathway antibodies  Parkin-Ubiquitin Proteasomal System Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram

Diseases associated with anti-TUBB2B antibody

 Disease Name  Pubmed Publications
 POLYMICROGYRIA, SYMMETRIC OR ASYMMETRIC Antibodies  >61149 publications with TUBB2B and POLYMICROGYRIA, SYMMETRIC OR ASYMMETRIC
 Malformations of Cortical Development Antibodies  >20 publications with TUBB2B and Malformations of Cortical Development
 Nervous System Malformations Antibodies  >18 publications with TUBB2B and Nervous System Malformations
 Atrophy Antibodies  >2 publications with TUBB2B and Atrophy
 Fibrosis Antibodies  >2 publications with TUBB2B and Fibrosis
 Urogenital Abnormalities Antibodies  >1 publications with TUBB2B and Urogenital Abnormalities
 Lung Neoplasms Antibodies  >1 publications with TUBB2B and Lung Neoplasms

Organs/Tissues associated with anti-TUBB2B antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >22 publications with TUBB2B and Brain
 Ganglia Antibodies  >7 publications with TUBB2B and Ganglia
 Muscle Antibodies  >4 publications with TUBB2B and Muscle
 Nerve Antibodies  >2 publications with TUBB2B and Nerve
 Intestine Antibodies  >1 publications with TUBB2B and Intestine
 Eye Antibodies  >1 publications with TUBB2B and Eye
 Lung Antibodies  >1 publications with TUBB2B and Lung
 Ovary Antibodies  >1 publications with TUBB2B and Ovary
 Embryonic Tissue Antibodies  >1 publications with TUBB2B and Embryonic Tissue
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