RAB1A Recombinant Protein – Cat# MBS717079

Ras-Related Protein Rab-1a (RAB1A) Recombinant Protein

Name: RAB1A Recombinant Protein; MyBioSource
Brand: MyBioSource
SKU: MBS717079
Price: 860 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS717079

Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity. More details

$860 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Ras-related protein Rab-1A (RAB1A), Recombinant Protein

Full Product Name

Recombinant human Ras-related protein Rab-1A

Product Gene Name

RAB1A recombinant protein

Product Synonym Names

Recombinant human Ras-related protein Rab-1A protein

Sequence

SSMNPEYDYL FKLLLIGDSG VGKSCLLLRF ADDTYTESYI STIGVDFKIR TIELDGKTIK LQIWDTAGQE RFRTITSSYY RGAHGIIVVY DVTDQESFNN VKQWLQEIDR YASENVNKLL VGNKCDLTTK KVVDYTTAKE FADSLGIPFL ETSAKNATNV EQSFMTMAAE IKKRMGPGAT AGGAEKSNVK IQSTPVKQSG GGCC-

Host

E Coli

Form/Format

Liquid containing glycerol

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, conserve at -20 or -80 degree C.

Molecular Weight

48 KD

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

Chromosome: 2; NC_000002.11 (65313988..65357435, complement). Location: 2p14

OMIM

179508

3D Structure

ModBase 3D Structure for P62820

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Product References and Citations for RAB1A recombinant protein

[1] "The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion."

Other Notes

Small volumes of RAB1A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB1A purchase

MBS717079 is a recombinant protein targeting RAB1A. Also known as Recombinant human Ras-related protein Rab-1A. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB1A. It may not necessarily be applicable to this product.

NCBI GI #

207442673

NCBI GeneID

5861

NCBI Accession #

NP_004152.1

UniProt Primary Accession #

P62820

UniProt Secondary Accession #

P11476; Q6FIE7; Q96N61; Q9Y3T2

UniProt Related Accession #

P62820

GenBank Nucleotide #

NM_004161.4

NCBI Official Full Name

Homo sapiens RAB1A, member RAS oncogene family (RAB1A), transcript variant 1, mRNA

NCBI Official Synonym Full Names

RAB1A, member RAS oncogene family

NCBI Official Symbol

RAB1A

NCBI Official Synonym Symbols

RAB1; YPT1

UniProt Protein Name

Ras-related protein Rab-1A

UniProt Synonym Protein Names

YPT1-related protein

Protein Family

Ras-related protein

UniProt Gene Name

RAB1A

UniProt Synonym Gene Names

RAB1

UniProt Entry Name

RAB1A_HUMAN

NCBI Protein Information

ras-related protein Rab-1A; YPT1-related protein; Rab GTPase YPT1 homolog; GTP binding protein Rab1a; RAB1, member RAS oncogene family

NCBI Summary for RAB1A

This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms. [provided by RefSeq, Oct 2008]

UniProt Comments for RAB1A

Function: Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity.

Subunit structure: May interact with YIPF5

By similarity.

Subcellular location: Golgi apparatus. Endoplasmic reticulum.

Post-translational modification: Phosphorylated by CDK1 kinase during mitosis. Ref.10 Ref.13 Ref.14Phosphocholinated at Ser-79 by L.pneumophila AnkX, leading to displace GDP dissociation inhibitors (GDI). Both GDP-bound and GTP-bound forms can be phosphocholinated. Dephosphocholinated by L.pneumophila Lem3, restoring accessibility to L.pneumophila GTPase effector LepB.

Sequence similarities: Belongs to the small GTPase superfamily. Rab family.

Research Articles on RAB1A

1. When bound to Rab1, LidA interfered with the covalent modification of Rab1 by phosphocholination or AMPylation, and it also blocked de-AMPylation of Rab1 by SidD and dephosphocholination by Lem3.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RAB1A recombinant protein

Reference Product	PubMed Publications
CHML recombinant protein	>1 publications with RAB1A and CHML

Pathways associated with RAB1A recombinant protein

Products by Pathway	Pathway Diagram
Legionellosis Pathway antibodies	Legionellosis Pathway Diagram
Legionellosis Pathway antibodies	Legionellosis Pathway Diagram
PLK1 Signaling Events Pathway antibodies	PLK1 Signaling Events Pathway Diagram

Diseases associated with RAB1A recombinant protein

Disease Name	Pubmed Publications
Carcinoma, Squamous Cell Antibodies	>2 publications with RAB1A and Carcinoma, Squamous Cell
Fibrosis Antibodies	>2 publications with RAB1A and Fibrosis
Nerve Degeneration Antibodies	>1 publications with RAB1A and Nerve Degeneration
Movement Disorders Antibodies	>1 publications with RAB1A and Movement Disorders
Sarcoma Antibodies	>1 publications with RAB1A and Sarcoma
Brain Diseases Antibodies	>1 publications with RAB1A and Brain Diseases
Multiple Myeloma Antibodies	>1 publications with RAB1A and Multiple Myeloma
Neoplasm Metastasis Antibodies	>1 publications with RAB1A and Neoplasm Metastasis

Organs/Tissues associated with RAB1A recombinant protein

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>6 publications with RAB1A and Muscle
Nerve Antibodies	>6 publications with RAB1A and Nerve
Brain Antibodies	>5 publications with RAB1A and Brain
Kidney Antibodies	>3 publications with RAB1A and Kidney
Pancreas Antibodies	>3 publications with RAB1A and Pancreas
Heart Antibodies	>3 publications with RAB1A and Heart
Mouth Antibodies	>2 publications with RAB1A and Mouth
Eye Antibodies	>2 publications with RAB1A and Eye
Blood Antibodies	>2 publications with RAB1A and Blood
Liver Antibodies	>2 publications with RAB1A and Liver