AHSA1 Recombinant Protein – Cat# MBS717092

Activator of 90 Kda Heat Shock Protein Atpase Homolog 1 (AHSA1) Recombinant Protein

Name: AHSA1 Recombinant Protein; MyBioSource
Brand: MyBioSource
SKU: MBS717092
Price: 1050 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS717092

Cochaperone that stimulates HSP90 ATPase activity By similarity. May affect a step in the endoplasmic reticulum to Golgi trafficking. More details

$1050 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1), Recombinant Protein

Full Product Name

Recombinant human Activator of 90 kDa heat shock protein ATPase homolog 1

Product Gene Name

AHSA1 recombinant protein

Product Synonym Names

Recombinant human Activator of 90 kDa heat shock protein ATPase homolog 1 protein

Sequence

MAKWGEGDPR WIVEERADAT NVNNWHWTER DASNWSTDKL KTLFLAVQVQ NEEGKCEVTE VSKLDGEASI NNRKGKLIFF YEWSVKLNWT GTSKSGVQYK GHVEIPNLSD ENSVDEVEIS VSLAKDEPDT NLVALMKEEG VKLLREAMGI YISTLKTEFT QGMILPTMNG ESVDPVGQPA LKTEERKAKP APSKTQARPV GVKIPTCKIT LKETFLTSPE ELYRVFTTQE LVQAFTHAPA TLEADRGGKF HMVDGNVSGE FTDLVPEKHI VMKWRFKSWP EGHFATITLT FIDKNGETEL CMEGRGIPAP EEERTRQGWQ RYYFEGIKQT FGYGARLF

Host

E Coli

Form/Format

Liquid containing glycerol

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, conserve at -20 or -80 degree C.

Molecular Weight

63 KD

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

Chromosome: 14; NC_000014.8 (77924373..77935815). Location: 14q24

OMIM

608466

3D Structure

ModBase 3D Structure for O95433

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Product References and Citations for AHSA1 recombinant protein

[1] "Isolation of a novel gene underexpressed in Down syndrome."

Other Notes

Small volumes of AHSA1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AHSA1 purchase

MBS717092 is a recombinant protein targeting AHSA1. Also known as Recombinant human Activator of 90 kDa heat shock protein ATPase homolog 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for AHSA1. It may not necessarily be applicable to this product.

NCBI GI #

224451069

NCBI GeneID

10598

NCBI Accession #

NP_036243.1

UniProt Primary Accession #

O95433

UniProt Secondary Accession #

Q96IL6; Q9P060; B2R9L2

UniProt Related Accession #

O95433

GenBank Nucleotide #

NM_012111.2

NCBI Official Full Name

Homo sapiens AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) (AHSA1), mRNA

NCBI Official Synonym Full Names

AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)

NCBI Official Symbol

AHSA1

NCBI Official Synonym Symbols

p38; AHA1; C14orf3

UniProt Protein Name

Activator of 90 kDa heat shock protein ATPase homolog 1

UniProt Synonym Protein Names

p38

Protein Family

Activator of 90 kDa heat shock protein ATPase

UniProt Gene Name

AHSA1

UniProt Synonym Gene Names

C14orf3; AHA1

UniProt Entry Name

AHSA1_HUMAN

NCBI Protein Information

activator of 90 kDa heat shock protein ATPase homolog 1

UniProt Comments for AHSA1

Function: Cochaperone that stimulates HSP90 ATPase activity

By similarity. May affect a step in the endoplasmic reticulum to Golgi trafficking.

Subunit structure: Interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatitis virus glycoprotein (VSV G). Interacts with GCH1. Interacts with SRPK1. Ref.8 Ref.9 Ref.10 Ref.11 Ref.12

Subcellular location: Cytoplasm › cytosol. Endoplasmic reticulum. Note: May transiently interact with the endoplasmic reticulum. Ref.8

Tissue specificity: Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta. Ref.8

Induction: By heat shock and treatment with the HSP90 inhibitor 17-demethoxygeldanamycin (17AAG). Ref.9

Sequence similarities: Belongs to the AHA1 family.

Research Articles on AHSA1

1. Data propose a model for Aha1 in the Hsp90 ATPase cycle where Aha1 regulates dwell time of Hsp90, and suggest Aha1 activity integrates chaperone function with client folding energetics by modulating ATPase sensitive dimer structural transitions.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with AHSA1 recombinant protein

Disease Name	Pubmed Publications
Fibrosis Antibodies	>3 publications with AHSA1 and Fibrosis
Neoplasms Antibodies	>2 publications with AHSA1 and Neoplasms
Cell Transformation, Neoplastic Antibodies	>1 publications with AHSA1 and Cell Transformation, Neoplastic

Organs/Tissues associated with AHSA1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>1 publications with AHSA1 and Kidney
Muscle Antibodies	>1 publications with AHSA1 and Muscle