TNFRSF8 Recombinant Protein – Cat# MBS717097

Tumor Necrosis Factor Receptor Superfamily Member 8 (TNFRSF8) Recombinant Protein

Name: TNFRSF8 Recombinant Protein; MyBioSource
Brand: MyBioSource
SKU: MBS717097
Price: 1080 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS717097

Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B. More details

$1080 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Tumor necrosis factor receptor superfamily member 8 (TNFRSF8), Recombinant Protein

Full Product Name

Recombinant human Tumor necrosis factor receptor superfamily member 8 protein

Product Gene Name

TNFRSF8 recombinant protein

Product Synonym Names

CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; CD30

Sequence

FPQDRPFEDT CHGNPSHYYD KAVRRCCYRC PMGLFPTQQC PQRPTDCRKQ CEPDYYLDEA DRCTACVTCS RDDLVEKTPC AWNSSRVCEC RPGMFCSTSA VNSCARCFFH SVCPAGMIVK FPGTAQKNTV CEPASPGVSP ACASPENCKE PSSGTIPQAK PTPVSPATSS ASTMPVRGGT RLAQEAASKL TRAPDSPSSV GRPSSDPGLS PTQPCPEGSG DCRKQCEPDY YLDEAGRCTA CVSCSRDDLV EKTPCAWNSS RTCECRPGMI CATSATNSCA RCVPYPICAA ETVTKPQDMA EKDTTFEAPP LGTQPDCNPT PENGEAPAST SPTQSLLVDS QASKTLPIPT SAPVALSSTG K

Host

E Coli

Form/Format

Liquid containing glycerol

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage,conserve at -20 degree C or -80 degree C.

Molecular Weight

66 KD

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

Chromosome: 1; NC_000001.10 (12123434..12204264). Location: 1p36

OMIM

153243

3D Structure

ModBase 3D Structure for P28908

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for TNFRSF8 recombinant protein

ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of TNFRSF8 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TNFRSF8 purchase

MBS717097 is a recombinant protein targeting TNFRSF8. Also known as Recombinant human Tumor necrosis factor receptor superfamily member 8 protein. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for TNFRSF8. It may not necessarily be applicable to this product.

NCBI GI #

68348710

NCBI GeneID

943

NCBI Accession #

NP_001234.2

UniProt Primary Accession #

P28908

UniProt Secondary Accession #

Q6P4D9; B1AN79

UniProt Related Accession #

P28908

GenBank Nucleotide #

NM_001243.3

NCBI Official Full Name

Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1, mRNA

NCBI Official Synonym Full Names

tumor necrosis factor receptor superfamily, member 8

NCBI Official Symbol

TNFRSF8

NCBI Official Synonym Symbols

CD30; Ki-1; D1S166E

UniProt Protein Name

Tumor necrosis factor receptor superfamily member 8

UniProt Synonym Protein Names

CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30

Protein Family

Tumor necrosis factor receptor superfamily

UniProt Gene Name

TNFRSF8

UniProt Synonym Gene Names

CD30; D1S166E

UniProt Entry Name

TNR8_HUMAN

NCBI Protein Information

tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30

NCBI Summary for TNFRSF8

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

UniProt Comments for TNFRSF8

Function: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.

Subunit structure: Interacts with TRAF1, TRAF2, TRAF3 and TRAF5. Ref.8 Ref.9 Ref.10 Ref.11

Subcellular location: Isoform Long: Cell membrane; Single-pass type I membrane protein. Isoform Short: Cytoplasm.

Post-translational modification: Phosphorylated on serine and tyrosine residues. Ref.12

Miscellaneous: Most specific Hodgkin disease associated antigen.

Sequence similarities: Contains 6 TNFR-Cys repeats.

Research Articles on TNFRSF8

1. Scattered or diffuse CD30 expression in T-MF was not associated with an absence of CXCR3 expression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TNFRSF8 recombinant protein

Reference Product	PubMed Publications
TNFSF8 recombinant protein	>2 publications with TNFRSF8 and TNFSF8
ALK recombinant protein	>1 publications with TNFRSF8 and ALK

Pathways associated with TNFRSF8 recombinant protein

Products by Pathway	Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
TNF-alpha/NF-kB Signaling Pathway antibodies	TNF-alpha/NF-kB Signaling Pathway Diagram

Diseases associated with TNFRSF8 recombinant protein

Disease Name	Pubmed Publications
Necrosis Antibodies	>7 publications with TNFRSF8 and Necrosis
Neoplasms Antibodies	>3 publications with TNFRSF8 and Neoplasms
Leukemia Antibodies	>2 publications with TNFRSF8 and Leukemia
Inflammation Antibodies	>2 publications with TNFRSF8 and Inflammation
Lung Diseases Antibodies	>1 publications with TNFRSF8 and Lung Diseases
Carcinoma Antibodies	>1 publications with TNFRSF8 and Carcinoma
Drug Toxicity Antibodies	>1 publications with TNFRSF8 and Drug Toxicity
Hodgkin Disease Antibodies	>1 publications with TNFRSF8 and Hodgkin Disease

Organs/Tissues associated with TNFRSF8 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>5 publications with TNFRSF8 and Blood
Mixed Antibodies	>1 publications with TNFRSF8 and Mixed
Lymph Node Antibodies	>1 publications with TNFRSF8 and Lymph Node
Lung Antibodies	>1 publications with TNFRSF8 and Lung