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Exostosin-Like 3 (EXTL3) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS717253

Probable glycosyltransferase. Required for the function of REG3A in regulating keratinocyte proliferation and differentiation. 1 Publication More details

$325 / 0.05 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Exostosin-like 3 (EXTL3), Recombinant Protein
Full Product Name
Recombinant Human Exostosin-like 3
Product Gene Name
Product Synonym Gene Name
EXTL1L; EXTR1; KIAA0519
Product Synonym Names
EXT-related protein 1; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminy; ltransferase; Hereditary multiple exostoses gene isolog; Multiple exostosis-like protein 3; Putative tumor suppressor protein EXTL3
Sequence
TGYTMLRNGG AGNGGQTCML RWSNRIRLTW LSFTLFVILV FFPLIAHYYL TTLDEADEAG KRIFGPRVGN ELCEVKHVLD LCRIRESVSE ELLQLEAKRQ ELNSEIAKLN LKIEACKKSI ENAKQDLLQL KNVISQTEHS YKELMAQNQP KLSLPIRLLP EKDDAGLPPP KATRGCRLHN CFDYSRCPLT SGFPVYVYDS DQFVFGSYLD PLVKQAFQAT ARANVYVTEN ADIACLYVIL VGEM
Host
E Coli
Form/Format
Liquid containing glycerol
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Molecular Weight
55kD
Sequence Positions
2-245
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
605744
3D Structure
ModBase 3D Structure for O43909
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Product References and Citations for EXTL3 recombinant protein

Identification of a third EXT-like gene (EXTL3)

Other Notes

Small volumes of EXTL3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EXTL3 purchase

MBS717253 is a recombinant protein targeting EXTL3. Also known as Recombinant Human Exostosin-like 3. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for EXTL3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
exostosin-like 3
NCBI Official Synonym Full Names
exostosin like glycosyltransferase 3
NCBI Official Symbol
EXTL3
NCBI Official Synonym Symbols
RPR; BOTV; REGR; EXTR1; EXTL1L
UniProt Protein Name
Exostosin-like 3
UniProt Synonym Protein Names
EXT-related protein 1; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Hereditary multiple exostoses gene isolog; Multiple exostosis-like protein 3; Putative tumor suppressor protein EXTL3
Protein Family
UniProt Gene Name
EXTL3
UniProt Synonym Gene Names
EXTL1L; EXTR1; KIAA0519
UniProt Entry Name
EXTL3_HUMAN
NCBI Protein Information
exostosin-like 3

NCBI Summary for EXTL3

This gene encodes a single-pass membrane protein which functions as a glycosyltransferase. The encoded protein catalyzes the transfer of N-acetylglucosamine to glycosaminoglycan chains. This reaction is important in heparin and heparan sulfate synthesis. Alternative splicing results in the multiple transcript variants. [provided by RefSeq, Nov 2012]
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UniProt Comments for EXTL3

EXTL3: Probable glycosyltransferase. Belongs to the glycosyltransferase 47 family.

Protein type: Membrane protein, integral; Glycan Metabolism - heparan sulfate biosynthesis; EC 2.4.1.223; Transferase

Chromosomal Location of Human Ortholog: 8p21

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane

Molecular Function: glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; metal ion binding; receptor activity

Biological Process: cellular protein metabolic process; glycosaminoglycan biosynthetic process; heparan sulfate proteoglycan biosynthetic process; positive regulation of cell growth; unfolded protein response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with EXTL3 recombinant protein

 Reference Product  PubMed Publications
 CSGALNACT2 recombinant protein  >1 publications with EXTL3 and CSGALNACT2
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