Human BTF3 Recombinant Protein – Cat# MBS717327

Transcription Factor BTF3 (BTF3) Human Recombinant Protein

Name: BTF3 Recombinant Protein; Transcription Factor BTF3; Human; MyBioSource
Brand: MyBioSource
SKU: MBS717327
Price: 315 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS717327

When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they erge from the ribosome and blocks their interaction with the signal recognition particle… More details

$315 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Transcription factor BTF3, Recombinant Protein

Full Product Name

Recombinant Human Transcription factor BTF3 protein

Product Gene Name

BTF3 recombinant protein

Product Synonym Names

Nascent polypeptide-associated complex subunit beta; NAC-beta; RNA polymerase B transcription factor 3

Sequence

TIMNQEKLAK LQAQVRIGGK GTARRKKKVV HRTATADDKK LQFSLKKLGV NNISGIEEVN MFTNQGTVIH FNNPKVQASL AANTFTITGH AETKQLTEML PSILNQLGAD SLTSLRRLAE ALPKQSVDGK APLATGEDDD DEVPDLVENF DEASKNEAN

Host

E Coli

Form/Format

Liquid containing glycerol

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

Molecular Weight

44.3 kDa

Sequence Positions

48-206aa; Partial

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

602542

3D Structure

ModBase 3D Structure for P20290

Product Categories/Family for BTF3 recombinant protein

Transcription

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Product References and Citations for BTF3 recombinant protein

Sequencing and expression of complementary DNA for the general transcription factor BTF3.Zheng X.M., Black D., Chambon P., Egly J.-M.Nature 344:556-559(1990)

Other Notes

Small volumes of BTF3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BTF3 purchase

MBS717327 is a recombinant protein targeting BTF3. Also known as Recombinant Human Transcription factor BTF3 protein. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for BTF3. It may not necessarily be applicable to this product.

NCBI GI #

83641885

NCBI GeneID

689

NCBI Accession #

NP_001032726.1

UniProt Primary Accession #

P20290

UniProt Secondary Accession #

Q13893; Q76M56; A8K510

UniProt Related Accession #

P20290

GenBank Nucleotide #

NM_001037637.1

NCBI Official Full Name

transcription factor BTF3 isoform A

NCBI Official Synonym Full Names

basic transcription factor 3

NCBI Official Symbol

BTF3

NCBI Official Synonym Symbols

NACB; BTF3a; BTF3b; BETA-NAC

UniProt Protein Name

Transcription factor BTF3

UniProt Synonym Protein Names

Nascent polypeptide-associated complex subunit beta; NAC-beta; RNA polymerase B transcription factor 3

Protein Family

Basic transcription factor

UniProt Gene Name

BTF3

UniProt Synonym Gene Names

NACB; NAC-beta

UniProt Entry Name

BTF3_HUMAN

NCBI Protein Information

transcription factor BTF3

NCBI Summary for BTF3

This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]

UniProt Comments for BTF3

BTF3: a general transcription factor. BTF3 can form a stable complex with RNA polymerase II. An interaction partner of protein kinase CK2. Required for the initiation of transcription. Expressed at high levels in glioblastoma multiforme. Overexpressed in the microsatellite instability (MIN) phenotypes in colorectal cancer. Up-regulated strongly in the mammary gland during pregnancy, suggesting an involvement in alveolar growth. Two alternatively spliced isoforms have been described.

Protein type: Transcription initiation complex; Transcription factor

Chromosomal Location of Human Ortholog: 5q13.2

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding

Biological Process: in utero embryonic development; protein transport; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter

Research Articles on BTF3

1. BTF3, HINT1, NDRG1 and ODC1 protein over-expression in human prostate cancer tissue

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with BTF3 recombinant protein

Disease Name	Pubmed Publications
Carcinoma Antibodies	>6 publications with BTF3 and Carcinoma
Brain Diseases Antibodies	>3 publications with BTF3 and Brain Diseases
Carcinoma, Squamous Cell Antibodies	>2 publications with BTF3 and Carcinoma, Squamous Cell
Pancreatic Neoplasms Antibodies	>1 publications with BTF3 and Pancreatic Neoplasms
Breast Neoplasms Antibodies	>1 publications with BTF3 and Breast Neoplasms
Liver Diseases Antibodies	>1 publications with BTF3 and Liver Diseases
Liver Neoplasms Antibodies	>1 publications with BTF3 and Liver Neoplasms
Fibrosis Antibodies	>1 publications with BTF3 and Fibrosis
Fatty Liver Antibodies	>1 publications with BTF3 and Fatty Liver
Carcinoma, Hepatocellular Antibodies	>1 publications with BTF3 and Carcinoma, Hepatocellular

Organs/Tissues associated with BTF3 recombinant protein

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>3 publications with BTF3 and Liver
Nerve Antibodies	>3 publications with BTF3 and Nerve
Embryonic Tissue Antibodies	>2 publications with BTF3 and Embryonic Tissue
Muscle Antibodies	>2 publications with BTF3 and Muscle
Lung Antibodies	>2 publications with BTF3 and Lung
Brain Antibodies	>2 publications with BTF3 and Brain
Lymph Node Antibodies	>1 publications with BTF3 and Lymph Node
Eye Antibodies	>1 publications with BTF3 and Eye
Mammary Gland Antibodies	>1 publications with BTF3 and Mammary Gland
Skin Antibodies	>1 publications with BTF3 and Skin