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Galactose-1-Phosphate Uridylyltransferase (GALT) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS718198

MBS718198 is a recombinant protein targeting GALT. Also known as Recombinant Human Galactose-1-phosphate uridylyltransferase. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$385 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Galactose-1-phosphate uridylyltransferase (GALT), Recombinant Protein
Full Product Name
Recombinant Human Galactose-1-phosphate uridylyltransferase
Product Gene Name
Product Synonym Names
UDP-glucose-hexose-1-phosphate uridylyltransferase
Sequence
MSRSGTDPQQ RQQASEADAA AATFRANDHQ HIRYNPLQDE WVLVSAHRMK RPWQGQVEPQ LLKTVPRHDP LNPLCPGAIR ANGEVNPQYD STFLFDNDFP ALQPDAPSPG PSDHPLFQAK SARGVCKVMC FHPWSDVTLP LMSVPEIRAV VDAWASVTEE LGAQYPWVQI FENKGAMMGC SNPHPHCQVW ASSFLPDIAQ REERSQQAYK SQHGEPLLME YSRQELLRKE RLVLTSEHWL VLVPFWATWP YQTLLLPRRH VRRLPELTPA ERDDLASIMK KLLTKYDNLF ETSFPYSMGW HGAPTGSEAG ANWNHWQLHA HYYPPLLRSA TVRKFMVGYE MLAQAQRDLT PEQAAERLRA LPEVHYHLGQ KDRETATIA
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Molecular Weight
59.4 kDa
Sequence Positions
1-379. Full length.
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
230400
3D Structure
ModBase 3D Structure for P07902

Product Categories/Family for GALT recombinant protein

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Product References and Citations for GALT recombinant protein

Cloning and characterization of a cDNA encoding human galactose-1-phosphate uridyl transferase.Reichardt J.K.V., Berg P.Mol. Biol. Med. 5:107-122(1988)

Other Notes

Small volumes of GALT recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GALT. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
galactose-1-phosphate uridylyltransferase isoform 1
NCBI Official Synonym Full Names
galactose-1-phosphate uridylyltransferase
NCBI Official Symbol
GALT
UniProt Protein Name
Galactose-1-phosphate uridylyltransferase
UniProt Synonym Protein Names
UDP-glucose--hexose-1-phosphate uridylyltransferase
UniProt Gene Name
GALT
UniProt Synonym Gene Names
Gal-1-P uridylyltransferase
UniProt Entry Name
GALT_HUMAN
NCBI Protein Information
galactose-1-phosphate uridylyltransferase

NCBI Summary for GALT

Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
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UniProt Comments for GALT

GALT: Defects in GALT are the cause of galactosemia (GALCT). Galactosemia is an inherited disorder of galactose metabolism that causes jaundice, cataracts, and mental retardation. Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

Protein type: Carbohydrate Metabolism - galactose; Motility/polarity/chemotaxis; Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC 2.7.7.12; Transferase

Chromosomal Location of Human Ortholog: 9p13

Cellular Component: cytosol; Golgi apparatus

Molecular Function: protein binding; UDP-glucose:hexose-1-phosphate uridylyltransferase activity; zinc ion binding

Biological Process: carbohydrate metabolic process; galactose catabolic process; galactose metabolic process; UDP-glucose catabolic process

Disease: Galactosemia
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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