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Gc-Rich Sequence DNA-Binding Factor 2 (GCFC2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS718398

The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the… More details

$1660 / 0.02 mg (E-Coli) +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GC-rich sequence DNA-binding factor 2 (GCFC2), Recombinant Protein
Full Product Name
Recombinant Human GC-rich sequence DNA-binding factor 2 (GCFC2)
Product Gene Name
GCFC2 recombinant protein
Sequence
MAHRPKRTFR QRAADSSDSD GAEESPAEPG APRELPVPGS AEEEPPSGGG RAQVAGLPHR VRGPRGRGRV WASSRRATKA APRADEGSES RTLDVSTDEE DKIHHSSESK DDQGLSSDSS SSLGEKELSS TVKIPDAAFI QAARRKRELA RAQDDYISLD VQHTSSISGM KRESEDDPES EPDDHEKRIP FTLRPQTLRQ RMAEESISRN EETSEESQED EKQDTWEQQQ MRKAVKIIEE RDIDLSCGNG SSKVKKFDTS ISFPPVNLEI IKKQLNTRLT LLQETHRSHL REYEKYVQDV KSSKSTIQNL ESSSNQALNC KFYKSMKIYV ENLIDCLNEK IINIQEIESS MHALLLKQAM TFMKRRQDEL KHESTYLQQL SRKDETSTSG NFSVDEKTQW ILEEIESRRT KRRQARVLSG NCNHQEGTSS DDELPSAEMI DFQKSQGDIL QKQKKVFEEV QDDFCNIQNI LLKFQQWREK FPDSYYEAFI SLCIPKLLNP LIRVQLIDWN PLKLESTGLK EMPWFKSVEE FMDSSVEDSK KESSSDKKVL SAIINKTIIP RLTDFVEFLW DPLSTSQTTS LITHCRVILE EHSTCENEVS KSRQDLLKSI VSRMKKAVED DVFIPLYPKS AVENKTSPHS KFQERQFWSG LKLFRNILLW NGLLTDDTLQ ELGLGKLLNR YLIIALLNAT PGPDVVKKCN QVAACLPEKW FENSAMRTSI PQLENFIQFL LQSAHKLSRS EFRDEVEEII LILVKIKALN QAESFIGEHH LDHLKSLIKE D
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
28,048 Da
Sequence Positions
1-781, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
189901
3D Structure
ModBase 3D Structure for P16383
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GCFC2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GCFC2 purchase

MBS718398 is a recombinant protein targeting GCFC2. Also known as Recombinant Human GC-rich sequence DNA-binding factor 2 (GCFC2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for GCFC2. It may not necessarily be applicable to this product.

NCBI GI #
318083361
NCBI GeneID
6936
NCBI Accession #
NP_001188263.1
UniProt Primary Accession #
P16383
UniProt Secondary Accession #
O95032; Q53TY0; Q6P2F2; A4UHQ8; A4UHQ9
UniProt Related Accession #
P16383
GenBank Nucleotide #
NM_001201334.1
NCBI Official Full Name
GC-rich sequence DNA-binding factor 2 isoform 2
NCBI Official Synonym Full Names
GC-rich sequence DNA-binding factor 2
NCBI Official Symbol
GCFC2
NCBI Official Synonym Symbols
GCF; TCF9; DNABF; C2orf3
UniProt Protein Name
GC-rich sequence DNA-binding factor 2
UniProt Synonym Protein Names
GC-rich sequence DNA-binding factor; Transcription factor 9; TCF-9
Protein Family
GC-rich sequence DNA-binding factor
UniProt Gene Name
GCFC2
UniProt Synonym Gene Names
C2orf3; GCF; TCF9; TCF-9
NCBI Protein Information
GC-rich sequence DNA-binding factor 2

UniProt Comments for GCFC2

Factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters. Involved in pre-mRNA splicing through regulating spliceosome C complex formation. May play a role during late-stage splicing events and turnover of excised inrons.
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Research Articles on GCFC2

1. Authors propose the GCF regulated transcriptional activity, at least in part, contributed to the upregulation of IER5 on radiation in HepG2 cells. The present findings provide insights into understanding the regulatory mechanisms of IER5.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GCFC2 recombinant protein

 Reference Product  PubMed Publications
 MRPL19 recombinant protein  >2 publications with GCFC2 and MRPL19
 DCDC2 recombinant protein  >1 publications with GCFC2 and DCDC2
 DYX1C1 recombinant protein  >1 publications with GCFC2 and DYX1C1
 KIAA0319 recombinant protein  >1 publications with GCFC2 and KIAA0319

Diseases associated with GCFC2 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with GCFC2 and Neoplasms
 Nervous System Diseases Antibodies  >2 publications with GCFC2 and Nervous System Diseases
 Neurodegenerative Diseases Antibodies  >1 publications with GCFC2 and Neurodegenerative Diseases
 Neurobehavioral Manifestations Antibodies  >1 publications with GCFC2 and Neurobehavioral Manifestations
 Brain Diseases Antibodies  >1 publications with GCFC2 and Brain Diseases
 Nerve Degeneration Antibodies  >1 publications with GCFC2 and Nerve Degeneration

Organs/Tissues associated with GCFC2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with GCFC2 and Blood
 Brain Antibodies  >3 publications with GCFC2 and Brain
 Nerve Antibodies  >2 publications with GCFC2 and Nerve
 Testis Antibodies  >1 publications with GCFC2 and Testis
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