Rat FCER1G Recombinant Protein – Cat# MBS718713

High Affinity Immunoglobulin Epsilon Receptor Subunit Gamma (FCER1G) Rat Recombinant Protein

Name: FCER1G Recombinant Protein; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS718713
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS718713

MBS718713 is a recombinant protein targeting Fcer1g. Also known as Recombinant Rat High affinity immunoglobulin epsilon receptor subunit gamma (Fcer1g). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

High affinity immunoglobulin epsilon receptor subunit gamma (Fcer1g), Recombinant Protein

Full Product Name

Recombinant Rat High affinity immunoglobulin epsilon receptor subunit gamma (Fcer1g)

Product Gene Name

Fcer1g recombinant protein

Product Synonym Gene Name

Fcer1g; Fce1g

Product Synonym Names

Recombinant High affinity immunoglobulin epsilon receptor subunit gamma (Fcer1g); High affinity immunoglobulin epsilon receptor subunit gamma; Fc receptor gamma-chain; FcRgamma Fc-epsilon RI-gamma IgE Fc receptor subunit gamma; FceRI gamma

Sequence

LGEPQ

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

9,765 Da

Sequence Positions

19-23

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

Chromosome: 13; NC_005112.3 (94228759..94233191, complement). Location: 13q24

3D Structure

ModBase 3D Structure for P20411

Species

Rattus norvegicus (Rat)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Fcer1g recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Fcer1g. It may not necessarily be applicable to this product.

NCBI GI #

196162692

NCBI GeneID

25441

NCBI Accession #

NP_001124473.1

UniProt Primary Accession #

P20411

UniProt Related Accession #

P20411

GenBank Nucleotide #

NM_001131001.1

NCBI Official Full Name

high affinity immunoglobulin epsilon receptor subunit gamma

NCBI Official Synonym Full Names

Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide

NCBI Official Symbol

Fcer1g

UniProt Protein Name

High affinity immunoglobulin epsilon receptor subunit gamma

UniProt Synonym Protein Names

Fc receptor gamma-chain; FcRgamma; Fc-epsilon RI-gamma; IgE Fc receptor subunit gamma

Protein Family

High affinity immunoglobulin epsilon receptor

UniProt Gene Name

Fcer1g

UniProt Synonym Gene Names

Fce1g; FcRgamma; FceRI gamma

UniProt Entry Name

FCERG_RAT

NCBI Protein Information

high affinity immunoglobulin epsilon receptor subunit gamma; fcRgamma; fceRI gamma; gamma polypeptide; fc-epsilon RI-gamma; Fc receptor gamma-chain; igE Fc receptor subunit gamma; Fc receptor, IgE, high affinity I, gamma polypeptide

NCBI Summary for Fcer1g

subunit of high-affinity receptor for immunoglobulin E; mediates the release of mediators responsible for allergic symptoms [RGD, Feb 2006]

UniProt Comments for Fcer1g

Function: Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by integrin

By similarity.

Subunit structure: IgE Fc receptor is a tetramer of an alpha chain, a beta chain, and two disulfide linked gamma chains. The gamma chain from Fc-epsilon-Ri are also subunits of other Fc receptors like FCGR1A

By similarity. Associated with CLEC6A

By similarity. Interacts with CLEC4E

By similarity. Interacts (via ITAM domain) with SYK (via SH2 domains); activates SYK, enabling integrin-mediated activation of neutrophils and macrophages

By similarity. Interacts with CD300LH; the interaction may be indirect

By similarity. Interacts with CD300LD

By similarity.

Subcellular location: Cell membrane; Single-pass type I membrane protein

By similarity.

Tissue specificity: Expressed in leukocytes and pinealocytes. Expression in the pineal gland does not undergo circadian variations. Ref.2

Sequence similarities: Belongs to the CD3Z/FCER1G family.Contains 1 ITAM domain.

Research Articles on Fcer1g

1. Phospholipase D1 activity by regulating phosphatidic acid formation controls the early signals initiated by FcepsilonRI aggregation that lead to mast cell degranulation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Fcer1g recombinant protein

Products by Pathway	Pathway Diagram
Asthma Pathway antibodies	Asthma Pathway Diagram
Asthma Pathway antibodies	Asthma Pathway Diagram
Fc Epsilon RI Signaling Pathway antibodies	Fc Epsilon RI Signaling Pathway Diagram
Fc Epsilon RI Signaling Pathway antibodies	Fc Epsilon RI Signaling Pathway Diagram
Natural Killer Cell Mediated Cytotoxicity Pathway antibodies	Natural Killer Cell Mediated Cytotoxicity Pathway Diagram
Natural Killer Cell Mediated Cytotoxicity Pathway antibodies	Natural Killer Cell Mediated Cytotoxicity Pathway Diagram
Tuberculosis Pathway antibodies	Tuberculosis Pathway Diagram
Tuberculosis Pathway antibodies	Tuberculosis Pathway Diagram

Diseases associated with Fcer1g recombinant protein

Disease Name	Pubmed Publications
Hypersensitivity Antibodies	>5 publications with Fcer1g and Hypersensitivity
Genetic Predisposition to Disease Antibodies	>5 publications with Fcer1g and Genetic Predisposition to Disease
Inflammation Antibodies	>3 publications with Fcer1g and Inflammation
Asthma Antibodies	>2 publications with Fcer1g and Asthma
Necrosis Antibodies	>2 publications with Fcer1g and Necrosis
Neoplasms Antibodies	>2 publications with Fcer1g and Neoplasms
Lung Diseases Antibodies	>2 publications with Fcer1g and Lung Diseases
Fibrosis Antibodies	>1 publications with Fcer1g and Fibrosis
Nervous System Malformations Antibodies	>1 publications with Fcer1g and Nervous System Malformations
Weight Gain Antibodies	>1 publications with Fcer1g and Weight Gain

Organs/Tissues associated with Fcer1g recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>2 publications with Fcer1g and Brain
Lung Antibodies	>1 publications with Fcer1g and Lung
Connective Tissue Antibodies	>1 publications with Fcer1g and Connective Tissue