Human HAL Recombinant Protein – Cat# MBS718753

Histidine Ammonia-Lyase (HAL) Human Recombinant Protein

Name: HAL Recombinant Protein; Histidine Ammonia-Lyase; Human; MyBioSource
Brand: MyBioSource
SKU: MBS718753
Price: 1475 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS718753

$1475 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Histidine ammonia-lyase (HAL), Recombinant Protein

Full Product Name

Recombinant Human Histidine ammonia-lyase (HAL)

Product Gene Name

HAL recombinant protein

Sequence

MPRYTVHVRG EWLAVPCQDA QLTVGWLGRE AVRRYIKNKP DNGGFTSVDD AHFLVRRCKG LGLLDNEDRL EVALENNEFV EVVIEGDAMS PDFIPSQPEG VYLYSKYREP EKYIELDGDR LTTEDLVNLG KGRYKIKLTP TAEKRVQKSR EVIDSIIKEK TVVYGITTGF GKFARTVIPI NKLQELQVNL VRSHSSGVGK PLSPERCRML LALRINVLAK GYSGISLETL KQVIEMFNAS CLPYVPEKGT VGASGDLAPL SHLALGLVGE GKMWSPKSGW ADAKYVLEAH GLKPVILKPK EGLALINGTQ MITSLGCEAV ERASAIARQA DIVAALTLEV LKGTTKAFDT DIHALRPHRG QIEVAFRFRS LLDSDHHPSE IAESHRFCDR VQDAYTLRCC PQVHGVVNDT IAFVKNIITT ELNSATDNPM VFANRGETVS GGNFHGEYPA KALDYLAIGI HELAAISERR IERLCNPSLS ELPAFLVAEG GLNSGFMIAH CTAAALVSEN KALCHPSSVD SLSTSAATED HVSMGGWAAR KALRVIEHVE QVLAIELLAA CQGIEFLRPL KTTTPLEKVY DLVRSVVRPW IKDRFMAPDI EAAHRLLLEQ KVWEVAAPYI EKYRMEHIPE SRPLSPTAFS LQFLHKKSTK IPESEDL

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

49,123 Da

Sequence Positions

1-657, Full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

235800

3D Structure

ModBase 3D Structure for P42357

Species

Human

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of HAL recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HAL purchase

MBS718753 is a recombinant protein targeting HAL. Also known as Recombinant Human Histidine ammonia-lyase (HAL). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for HAL. It may not necessarily be applicable to this product.

NCBI GI #

385251407

NCBI GeneID

3034

NCBI Accession #

NP_001245262.1

UniProt Primary Accession #

P42357

UniProt Secondary Accession #

Q4VB92; Q4VB93; B4DQC1; B4E0V8; F5GXF2; F5H1U5

UniProt Related Accession #

P42357

GenBank Nucleotide #

NM_001258333.1

NCBI Official Full Name

histidine ammonia-lyase isoform 2

NCBI Official Synonym Full Names

histidine ammonia-lyase

NCBI Official Symbol

HAL

NCBI Official Synonym Symbols

HIS; HSTD

UniProt Protein Name

Histidine ammonia-lyase

Protein Family

Probable histidine ammonia-lyase

UniProt Gene Name

HAL

UniProt Synonym Gene Names

HIS; Histidase

NCBI Protein Information

histidine ammonia-lyase

NCBI Summary for HAL

Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Research Articles on HAL

1. Three LoF mutations in HAL were associated with increased histidine levels, which in turn were shown to be inversely related to the risk of CHD among both African Americans and European Americans.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HAL recombinant protein

Reference Product	PubMed Publications
AMDHD1 recombinant protein	>1 publications with HAL and AMDHD1

Pathways associated with HAL recombinant protein

Products by Pathway	Pathway Diagram
Histidine Catabolism Pathway antibodies	Histidine Catabolism Pathway Diagram
Histidine Metabolism Pathway antibodies	Histidine Metabolism Pathway Diagram
Histidine Metabolism Pathway antibodies	Histidine Metabolism Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Amino Acids And Derivatives Pathway antibodies	Metabolism Of Amino Acids And Derivatives Pathway Diagram
Histidine Degradation Pathway antibodies	Histidine Degradation Pathway Diagram
Histidine Degradation III Pathway antibodies	Histidine Degradation III Pathway Diagram
Histidine Degradation VI Pathway antibodies	Histidine Degradation VI Pathway Diagram

Diseases associated with HAL recombinant protein

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>92 publications with HAL and Cardiovascular Diseases
Liver Diseases Antibodies	>81 publications with HAL and Liver Diseases
Gastrointestinal Diseases Antibodies	>76 publications with HAL and Gastrointestinal Diseases
Liver Neoplasms Antibodies	>58 publications with HAL and Liver Neoplasms
Inflammation Antibodies	>52 publications with HAL and Inflammation
Neoplasms, Experimental Antibodies	>52 publications with HAL and Neoplasms, Experimental
Heart Diseases Antibodies	>43 publications with HAL and Heart Diseases
Poisoning Antibodies	>38 publications with HAL and Poisoning
Drug-Related Side Effects and Adverse Reactions Antibodies	>36 publications with HAL and Drug-Related Side Effects and Adverse Reactions
Necrosis Antibodies	>32 publications with HAL and Necrosis

Organs/Tissues associated with HAL recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>419 publications with HAL and Blood
Liver Antibodies	>142 publications with HAL and Liver
Muscle Antibodies	>117 publications with HAL and Muscle
Heart Antibodies	>74 publications with HAL and Heart
Skin Antibodies	>56 publications with HAL and Skin
Eye Antibodies	>14 publications with HAL and Eye
Pancreas Antibodies	>4 publications with HAL and Pancreas
Testis Antibodies	>2 publications with HAL and Testis