Human ADRA1D Recombinant Protein – Cat# MBS718864

Alpha-1d Adrenergic Receptor (ADRA1D) Human Recombinant Protein

Name: ADRA1D Recombinant Protein; Alpha-1d Adrenergic Receptor; Human; MyBioSource
Brand: MyBioSource
SKU: MBS718864
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS718864

MBS718864 is a recombinant protein targeting ADRA1D. Also known as Recombinant Human Alpha-1D adrenergic receptor (ADRA1D). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Alpha-1D adrenergic receptor (ADRA1D), Recombinant Protein

Full Product Name

Recombinant Human Alpha-1D adrenergic receptor (ADRA1D)

Product Gene Name

ADRA1D recombinant protein

Product Synonym Gene Name

ADRA1D; ADRA1A

Product Synonym Names

Recombinant Alpha-1D adrenergic receptor (ADRA1D); Alpha-1D adrenergic receptor; Alpha-1A adrenergic receptor Alpha-1D adrenoreceptor; Alpha-1D adrenoceptor Alpha-adrenergic receptor 1a

Sequence

MTFRDLLSVS FEGPRPDSSA GGSSAGGGGG SAGGAAPSEG PAVGGVPGGA GGGGGVVGAG SGEDNRSSAG EPGSAGAGGD VNGTAAVGGL VVSAQGVGVG VFLAAFILMA VAGNLLVILS VACNRHLQTV TNYFIVNLAV ADLLLSATVL PFSATMEVLG FWAFGRAFCD VWAAVDVLCC TASILSLCTI SVDRYVGVRH SLKYPAIMTE RKAAAILALL WVVALVVSVG PLLGWKEPVP PDERFCGITE EAGYAVFSSV CSFYLPMAVI VVMYCRVYVV ARSTTRSLEA GVKRERGKAS EVVLRIHCRG AATGADGAHG MRSAKGHTFR SSLSVRLLKF SREKKAAKTL AIVVGVFVLC WFPFFFVLPL GSLFPQLKPS EGVFKVIFWL GYFNSCVNPL IYPCSSREFK RAFLRLLRCQ CRRRRRRRPL WRVYGHHWRA STSGLRQDCA PSSGDAPPGA PLALTALPDP DPEPPGTPEM QAPVASRRKP PSAFREWRLL GPFRRPTTQL RAKVSSLSHK IRAGGAQRAE AACAQRSEVE AVSLGVPHEV AEGATCQAYE LADYSNLRET DI

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

60,463 Da

Sequence Positions

1-572

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

Chromosome: 20; NC_000020.10 (4201278..4229659, complement). Location: 20p13

OMIM

104219

3D Structure

ModBase 3D Structure for P25100

Species

Homo sapiens (Human)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ADRA1D recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ADRA1D. It may not necessarily be applicable to this product.

NCBI GI #

4501957

NCBI GeneID

146

NCBI Accession #

NP_000669.1

UniProt Primary Accession #

P25100

UniProt Secondary Accession #

Q9NPY0

UniProt Related Accession #

P25100

GenBank Nucleotide #

NM_000678.3

NCBI Official Full Name

alpha-1D adrenergic receptor

NCBI Official Synonym Full Names

adrenoceptor alpha 1D

NCBI Official Symbol

ADRA1D

NCBI Official Synonym Symbols

DAR; ADRA1; ADRA1A; ADRA1R; ALPHA1; dJ779E11.2

UniProt Protein Name

Alpha-1D adrenergic receptor

UniProt Synonym Protein Names

Alpha-1A adrenergic receptor; Alpha-1D adrenoreceptor; Alpha-1D adrenoceptor; Alpha-adrenergic receptor 1a

Protein Family

Alpha-1D adrenergic receptor

UniProt Gene Name

ADRA1D

UniProt Synonym Gene Names

ADRA1A; Alpha-1D adrenoceptor

UniProt Entry Name

ADA1D_HUMAN

NCBI Protein Information

alpha-1D adrenergic receptor; alpha-1D adrenoceptor; alpha-1D adrenoreceptor; alpha-1A adrenergic receptor; alpha-1D-adrenergic receptor; alpha-adrenergic receptor 1a; adrenergic, alpha-1A-, receptor; adrenergic, alpha-1D-, receptor; adrenergic, alpha -1D-, receptor

NCBI Summary for ADRA1D

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region. [provided by RefSeq, Jul 2008]

UniProt Comments for ADRA1D

Function: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

Subcellular location: Cell membrane; Multi-pass membrane protein.

Sequence similarities: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1D sub-subfamily.

Research Articles on ADRA1D

1. Data show that alpha-dystrobrevin-1 recruits alpha-catulin, which supersensitizes alpha(1D)-AR functional responses by recruiting effector molecules to the signalosome.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ADRA1D recombinant protein

Reference Product	PubMed Publications
ADRA1A recombinant protein	>151 publications with ADRA1D and ADRA1A
NOS1 recombinant protein	>1 publications with ADRA1D and NOS1

Pathways associated with ADRA1D recombinant protein

Products by Pathway	Pathway Diagram
Adrenoceptors Pathway antibodies	Adrenoceptors Pathway Diagram
Amine Ligand-binding Receptors Pathway antibodies	Amine Ligand-binding Receptors Pathway Diagram
Calcium Regulation In The Cardiac Cell Pathway antibodies	Calcium Regulation In The Cardiac Cell Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (12/13) Signalling Events Pathway antibodies	G Alpha (12/13) Signalling Events Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram

Diseases associated with ADRA1D recombinant protein

Disease Name	Pubmed Publications
Hypertension Antibodies	>14 publications with ADRA1D and Hypertension
Urologic Diseases Antibodies	>8 publications with ADRA1D and Urologic Diseases
Heart Failure Antibodies	>4 publications with ADRA1D and Heart Failure
Prostatic Hyperplasia Antibodies	>4 publications with ADRA1D and Prostatic Hyperplasia
Hypertension, Renal Antibodies	>4 publications with ADRA1D and Hypertension, Renal
Nervous System Diseases Antibodies	>4 publications with ADRA1D and Nervous System Diseases
Hyperplasia Antibodies	>4 publications with ADRA1D and Hyperplasia
Necrosis Antibodies	>3 publications with ADRA1D and Necrosis
Kidney Diseases Antibodies	>3 publications with ADRA1D and Kidney Diseases
Heart Diseases Antibodies	>3 publications with ADRA1D and Heart Diseases

Organs/Tissues associated with ADRA1D recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>17 publications with ADRA1D and Brain
Prostate Antibodies	>8 publications with ADRA1D and Prostate
Eye Antibodies	>4 publications with ADRA1D and Eye
Bone Antibodies	>1 publications with ADRA1D and Bone