Rat TAP1 Recombinant Protein – Cat# MBS718962

Antigen Peptide Transporter 1 (TAP1) Rat Recombinant Protein

Name: TAP1 Recombinant Protein; Antigen Peptide Transporter 1; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS718962
Price: 3405 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS718962

MBS718962 is a recombinant protein targeting Tap1. Also known as Recombinant Rat Antigen peptide transporter 1 (Tap1), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$3405 / 1 mg (E-Coli) +4 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Antigen peptide transporter 1 (Tap1), Recombinant Protein

Full Product Name

Recombinant Rat Antigen peptide transporter 1 (Tap1), partial

Product Gene Name

Tap1 recombinant protein

Sequence

MAAHAWPTAA LLLLLVDWLL LRPVLPGIFS LLVPEVPLLR VWAVGLSRWA ILGLGVRGVL GVTAGARGWL AALQPLVAAL GLALPGLASF RKLSAWGALR EGDNAGLLHW NSRLDAFVLS YVAALPAAAL WHKLGGFWAP SGHKGAGDML CRMLGFLDSK KGRLHLVLVL LILSCLGEMA IPFFTGRITD WILQDKTAPS FARNMWLMCI LTIASTVLEF AGDGIYNITM GHMHSRVHGE VFRAVLHQET GFFLKNPTGS ITSRVTEDTS NVCESISDKL NLFLWYLGRG LCLLAFMIWG SFYLTVVTLL SLPLLFLLPR RLGKVYQSLA VKVQESLAKS TQVALEALSA MPTVRSFANE EGEAQKFRQK LEEMKPLNKK EALAYVTEVW TMSVSGMLLK VGILYLGGQL VVRGAVSSGN LVSFVLYQLQ FTRAVEVLLS IYPSMQKSVG ASEKIFEYLD RTPCSPLSGS LAPLNMKGLV KFQDVSFAYP NHPNVQVLQG LTFTLYPGKV TALVGPNGSG KSTVAALLQN LYQPTGGKVL LDGEPLVQYD HHYLHTQVAA VGQEPLLFGR SFRENIAYGL TRTPTMEEIT AVAMESGAHD FISGFPQGYD TEVGETGNQL SGGQRQAVAL ARALIRKPRL LILDDATSAL DAGNQLRVQR LLYESPEWAS RTVLLITQQL SLAERAHHIL FLKEGSVCEQ GTHLQLMERG GCYRSMVEAL AAPSD

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

79,150 Da

Sequence Positions

1-725

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for P36370

Species

Rattus norvegicus (Rat)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Tap1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Tap1. It may not necessarily be applicable to this product.

NCBI GI #

2506117

NCBI GeneID

24811

NCBI Accession #

P36370.2

UniProt Primary Accession #

P36370

UniProt Related Accession #

P36370

NCBI Official Full Name

Antigen peptide transporter 1

NCBI Official Synonym Full Names

transporter 1, ATP binding cassette subfamily B member

NCBI Official Symbol

Tap1

NCBI Official Synonym Symbols

Cim; Tap2; Abcb2

UniProt Protein Name

Antigen peptide transporter 1

UniProt Synonym Protein Names

ATP-binding cassette sub-family B member 2; Peptide transporter TAP1

Protein Family

Antigen peptide transporter

UniProt Gene Name

Tap1

UniProt Synonym Gene Names

Abcb2; Mtp1; APT1

NCBI Protein Information

antigen peptide transporter 1

NCBI Summary for Tap1

has similarity to multidrug resistant transporters; may transport antigenic peptides across the endoplasmic reticulum membrane in preparation for MHC class I presentation [RGD, Feb 2006]

UniProt Comments for Tap1

Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin ().

Research Articles on Tap1

1. Study compared the biochemical properties of the nucleotide-binding domains (NBD) of human and rat TAP1; suggests that although the D-helix sequence is not conserved in ABC transporters, its precise positioning within the NBD structure has a critical role in NBD dimerization.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Tap1 recombinant protein

Products by Pathway	Pathway Diagram
ABC Transporters Pathway antibodies	ABC Transporters Pathway Diagram
ABC Transporters Pathway antibodies	ABC Transporters Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway antibodies	Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway Diagram
Antigen Processing And Presentation Pathway antibodies	Antigen Processing And Presentation Pathway Diagram
Antigen Processing And Presentation Pathway antibodies	Antigen Processing And Presentation Pathway Diagram
Antigen Processing-Cross Presentation Pathway antibodies	Antigen Processing-Cross Presentation Pathway Diagram
Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies	Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
ER-Phagosome Pathway antibodies	ER-Phagosome Pathway Diagram
Herpes Simplex Infection Pathway antibodies	Herpes Simplex Infection Pathway Diagram

Organs/Tissues associated with Tap1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>43 publications with Tap1 and Lung
Spleen Antibodies	>42 publications with Tap1 and Spleen
Thymus Antibodies	>36 publications with Tap1 and Thymus
Liver Antibodies	>33 publications with Tap1 and Liver
Heart Antibodies	>10 publications with Tap1 and Heart
Pancreas Antibodies	>4 publications with Tap1 and Pancreas
Eye Antibodies	>3 publications with Tap1 and Eye
Ovary Antibodies	>3 publications with Tap1 and Ovary
Small Intestine Antibodies	>2 publications with Tap1 and Small Intestine
Adrenal Gland Antibodies	>2 publications with Tap1 and Adrenal Gland