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Replication Protein A 14 Kda Subunit (RPA3) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS719965

Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Ref.7 Ref.9 Functions as component of the alternative replication protein A complex (aRPA). aRPA binds… More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Replication protein A 14 kDa subunit (RPA3), Polyclonal Antibody
Full Product Name
Rabbit anti-human Replication protein A 14 kDa subunit polyclonal Antibody, FITC
Product Gene Name
anti-RPA3 antibody
Product Synonym Names
Replication factor A protein 3.RPA3; REPA3; RPA14
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: Replication protein A 14 kDa subunit (MBS719989)
FITC Conjugated Antibody: Replication protein A 14 kDa subunit (MBS719965)
Molecular Weight
13,569 Da
OMIM
179837
3D Structure
ModBase 3D Structure for P35244
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
FITC
Immunogen
Recombinant human Replication protein A 14 kDa subunit protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-30409 / sc-46623 / sc-46507 / sc-30411
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-RPA3 antibody
ELISA (EIA)

Other Notes

Small volumes of anti-RPA3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RPA3 purchase

MBS719965 is an antibody targeting RPA3. Also known as Rabbit anti-human Replication protein A 14 kDa subunit polyclonal Antibody, FITC. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RPA3. It may not necessarily be applicable to this product.

NCBI GI #
4506587
NCBI GeneID
6119
NCBI Accession #
NP_002938.1
UniProt Primary Accession #
P35244
UniProt Secondary Accession #
Q549U6
UniProt Related Accession #
P35244
GenBank Nucleotide #
NM_002947.4
NCBI Official Full Name
replication protein A 14 kDa subunit
NCBI Official Synonym Full Names
replication protein A3
NCBI Official Symbol
RPA3
NCBI Official Synonym Symbols
REPA3; RP-A p14
UniProt Protein Name
Replication protein A 14 kDa subunit
UniProt Synonym Protein Names
Replication factor A protein 3; RF-A protein 3
Protein Family
Replication protein
UniProt Gene Name
RPA3
UniProt Synonym Gene Names
REPA3; RPA14; RP-A p14; RF-A protein 3
UniProt Entry Name
RFA3_HUMAN
NCBI Protein Information
replication protein A 14 kDa subunit

UniProt Comments for RPA3

RPA3: Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.

Chromosomal Location of Human Ortholog: 7p22

Cellular Component: DNA replication factor A complex; nucleoplasm

Molecular Function: damaged DNA binding; protein binding; single-stranded DNA binding

Biological Process: base-excision repair; bypass DNA synthesis; DNA damage response, detection of DNA damage; DNA repair; DNA replication; DNA strand elongation during DNA replication; double-strand break repair; double-strand break repair via homologous recombination; error-prone postreplication DNA repair; G1/S transition of mitotic cell cycle; mismatch repair; mitotic cell cycle; nucleotide-excision repair; nucleotide-excision repair, DNA gap filling; nucleotide-excision repair, DNA incision; regulation of cell proliferation; regulation of mitotic cell cycle; telomere maintenance; telomere maintenance via recombination; telomere maintenance via semi-conservative replication; transcription-coupled nucleotide-excision repair
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Research Articles on RPA3

1. The allele "T" of rs6947203 in the RPA3 gene acts as a protective allele in glioma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RPA3 antibody

 Reference Product  PubMed Publications
 RPA2 antibody  >38 publications with RPA3 and RPA2
 RPA1 antibody  >28 publications with RPA3 and RPA1
 RPA4 antibody  >6 publications with RPA3 and RPA4
 PCNA antibody  >3 publications with RPA3 and PCNA
 RAD51 antibody  >1 publications with RPA3 and RAD51
 POLD1 antibody  >1 publications with RPA3 and POLD1

Pathways associated with anti-RPA3 antibody

 Products by Pathway  Pathway Diagram
 Activation Of ATR In Response To Replication Stress Pathway antibodies  Activation Of ATR In Response To Replication Stress Pathway Diagram
 Activation Of The Pre-replicative Complex Pathway antibodies  Activation Of The Pre-replicative Complex Pathway Diagram
 Base Excision Repair Pathway antibodies  Base Excision Repair Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cellular Response To Heat Stress Pathway antibodies  Cellular Response To Heat Stress Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Chromosome Maintenance Pathway antibodies  Chromosome Maintenance Pathway Diagram
 DNA Damage Bypass Pathway antibodies  DNA Damage Bypass Pathway Diagram

Diseases associated with anti-RPA3 antibody

 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >2 publications with RPA3 and Brain Diseases
 Cell Transformation, Neoplastic Antibodies  >2 publications with RPA3 and Cell Transformation, Neoplastic
 Neoplasm Metastasis Antibodies  >1 publications with RPA3 and Neoplasm Metastasis
 Ovarian Neoplasms Antibodies  >1 publications with RPA3 and Ovarian Neoplasms
 Precancerous Conditions Antibodies  >1 publications with RPA3 and Precancerous Conditions
 Breast Neoplasms Antibodies  >1 publications with RPA3 and Breast Neoplasms
 Weight Loss Antibodies  >1 publications with RPA3 and Weight Loss
 Kidney Diseases Antibodies  >1 publications with RPA3 and Kidney Diseases

Organs/Tissues associated with anti-RPA3 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >7 publications with RPA3 and Brain
 Blood Antibodies  >3 publications with RPA3 and Blood
 Muscle Antibodies  >2 publications with RPA3 and Muscle
 Heart Antibodies  >2 publications with RPA3 and Heart
 Lymph Antibodies  >1 publications with RPA3 and Lymph
 Skin Antibodies  >1 publications with RPA3 and Skin
 Lymph Node Antibodies  >1 publications with RPA3 and Lymph Node
 Kidney Antibodies  >1 publications with RPA3 and Kidney
 Lung Antibodies  >1 publications with RPA3 and Lung
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