Interleukin 31 (IL 31) ELISA Kit for Human

Name: Human IL 31 ELISA Kit; Interleukin 31; MyBioSource
Brand: MyBioSource
SKU: MBS723949
Price: 580 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS723949

MBS723949 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interleukin 31 (IL 31) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or… More details

$580 / 48-Strip-Wells-(Competitive) +1 FREE 8GB USB

Product Documentation

Sample Competitive Manual Insert View PDF

Sample Sandwich Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Interleukin 31 (IL 31), ELISA Kit

Full Product Name

Human Interleukin 31 ELISA Kit

Product Gene Name

IL 31 elisa kit

Species Reactivity

Human

Assay Type

Competitive or Sandwich

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

50-1000pg/mL

Sensitivity

1.0pg/mL

Preparation and Storage

Store all reagents at 2-8 degree C.

Molecular Weight

18,205 Da

OMIM

609509

Sample Preparation

We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team

Highest Standards

500pg/mL

Concentration of Standards

Concentration of Standards||0,25,50,100,250,500pg/mL

Product Categories/Family for IL 31 elisa kit

Immunology

ISO Certification

Manufactured in an ISO 13485:2016 Certified Laboratory.

Other Notes

Small volumes of IL 31 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL 31. It may not necessarily be applicable to this product.

NCBI GI #

62122911

NCBI GeneID

386653

NCBI Accession #

NP_001014358.1

UniProt Secondary Accession #

A2RUQ1

UniProt Related Accession #

Q6EBC2

GenBank Nucleotide #

NM_001014336.1

NCBI Official Full Name

interleukin-31

NCBI Official Synonym Full Names

interleukin 31

NCBI Official Symbol

IL31

NCBI Official Synonym Symbols

IL-31

UniProt Protein Name

Interleukin-31

Protein Family

Interleukin-31 receptor

UniProt Gene Name

IL31

UniProt Synonym Gene Names

IL-31

UniProt Entry Name

IL31_HUMAN

NCBI Protein Information

interleukin-31

NCBI Summary for IL 31

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008]

UniProt Comments for IL 31

IL31: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12q24.31

Cellular Component: extracellular space

Molecular Function: cytokine activity

Biological Process: immune system process

Research Articles on IL 31

1. EGFR-TK inhibitors could cause keratinocytes injury, the release of IL-33 and the consequent interaction with its receptor on mast cells, that induces the secretion of several factors capable to cause skin manifestations, included IL-31

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IL 31 elisa kit

Reference Product	PubMed Publications
IL31RA elisa kit	>14 publications with IL 31 and IL31RA
OSMR elisa kit	>8 publications with IL 31 and OSMR
IL6ST elisa kit	>1 publications with IL 31 and IL6ST

Diseases associated with IL 31 elisa kit

Disease Name	Pubmed Publications
Dermatitis Antibodies	>46 publications with IL 31 and Dermatitis
Dermatitis, Atopic Antibodies	>41 publications with IL 31 and Dermatitis, Atopic
Hypersensitivity Antibodies	>40 publications with IL 31 and Hypersensitivity
Inflammation Antibodies	>23 publications with IL 31 and Inflammation
Lung Diseases Antibodies	>7 publications with IL 31 and Lung Diseases
Respiratory Hypersensitivity Antibodies	>6 publications with IL 31 and Respiratory Hypersensitivity
Dermatitis, Contact Antibodies	>5 publications with IL 31 and Dermatitis, Contact
Necrosis Antibodies	>3 publications with IL 31 and Necrosis
Brain Diseases Antibodies	>3 publications with IL 31 and Brain Diseases
Melanoma Antibodies	>2 publications with IL 31 and Melanoma