Parathyroid Hormone Related (PTHRP) ELISA Kit for Donkey

Name: Donkey PTHRP ELISA Kit; Parathyroid Hormone Related; MyBioSource
Brand: MyBioSource
SKU: MBS072578
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS072578

MBS072578 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Parathyroid Hormone Related Protein (PTHRP) ELISA Kit target analytes in biological samples. The concentration gradients… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Parathyroid Hormone Related Protein (PTHRP), ELISA Kit

Full Product Name

Donkey Parathyroid Hormone Related Protein ELISA Kit

Product Gene Name

PTHRP elisa kit

Species Reactivity

Donkey

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

20,194 Da

Chromosome Location

Chromosome: 12; NC_000012.11 (28111017..28124916, complement). Location: 12p12.1-p11.2

OMIM

168470

3D Structure

ModBase 3D Structure for P12272

Other Notes

Small volumes of PTHRP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PTHRP. It may not necessarily be applicable to this product.

NCBI GI #

39995093

NCBI GeneID

5744

NCBI Accession #

NP_945317.1

UniProt Primary Accession #

P12272

UniProt Secondary Accession #

Q15251; Q6FH74

UniProt Related Accession #

P12272

GenBank Nucleotide #

NM_198966.1

NCBI Official Full Name

parathyroid hormone-related protein isoform 1 preproprotein

NCBI Official Synonym Full Names

parathyroid hormone-like hormone

NCBI Official Symbol

PTHLH

NCBI Official Synonym Symbols

HHM; PLP; BDE2; PTHR; PTHRP

UniProt Protein Name

Parathyroid hormone-related protein

UniProt Synonym Protein Names

Parathyroid hormone-like protein; PLPCleaved into the following 3 chains:PTHrP[1-36]PTHrP[38-94]Osteostatin; Alternative name(s):; PTHrP[107-139]

Protein Family

Parathyroid hormone-related protein

UniProt Gene Name

PTHLH

UniProt Synonym Gene Names

PTHRP; PTH-rP; PTHrP; PLP

UniProt Entry Name

PTHR_HUMAN

NCBI Protein Information

parathyroid hormone-related protein; PTH-rP; osteostatin; PTH-related protein; parathyroid hormone-like related protein

NCBI Summary for PTHRP

The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone. [provided by RefSeq, Jul 2008]

UniProt Comments for PTHRP

PTHrP: a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Three alternatively spliced isoforms have been described.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 12p12.1-p11.2

Cellular Component: nucleoplasm; Golgi apparatus; extracellular space; cytoplasm; extracellular region

Molecular Function: peptide hormone receptor binding; hormone activity

Biological Process: epidermis development; negative regulation of transcription factor activity; negative regulation of chondrocyte differentiation; female pregnancy; G-protein signaling, adenylate cyclase activating pathway; osteoblast development; negative regulation of cell proliferation; cAMP metabolic process; epithelial cell differentiation; cell-cell signaling; regulation of gene expression; positive regulation of cell proliferation; positive regulation of cAMP biosynthetic process; protein processing; alveolus development; surfactant homeostasis; skeletal development; endoderm development; endochondral ossification

Disease: Brachydactyly, Type E2

Research Articles on PTHRP

1. PTHrP increases the promoter activity of the integrin alpha6 and beta4 subunits.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PTHRP elisa kit

Reference Product	PubMed Publications
IHH elisa kit	>20 publications with PTHRP and IHH
PTH1R elisa kit	>14 publications with PTHRP and PTH1R
IL6 elisa kit	>2 publications with PTHRP and IL6
PTH2R elisa kit	>2 publications with PTHRP and PTH2R
PTCH1 elisa kit	>1 publications with PTHRP and PTCH1

Pathways associated with PTHRP elisa kit

Products by Pathway	Pathway Diagram
Class B/2 (Secretin Family Receptors) Pathway antibodies	Class B/2 (Secretin Family Receptors) Pathway Diagram
Endochondral Ossification Pathway antibodies	Endochondral Ossification Pathway Diagram
G Alpha (s) Signalling Events Pathway antibodies	G Alpha (s) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram
Signaling Events Mediated By The Hedgehog Family Pathway antibodies	Signaling Events Mediated By The Hedgehog Family Pathway Diagram

Diseases associated with PTHRP elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>739 publications with PTHRP and Neoplasms
Hypercalcemia Antibodies	>610 publications with PTHRP and Hypercalcemia
Bone Resorption Antibodies	>139 publications with PTHRP and Bone Resorption
Breast Neoplasms Antibodies	>122 publications with PTHRP and Breast Neoplasms
Carcinoma, Squamous Cell Antibodies	>112 publications with PTHRP and Carcinoma, Squamous Cell
Lung Neoplasms Antibodies	>102 publications with PTHRP and Lung Neoplasms
Lung Diseases Antibodies	>88 publications with PTHRP and Lung Diseases
Kidney Diseases Antibodies	>67 publications with PTHRP and Kidney Diseases
Necrosis Antibodies	>48 publications with PTHRP and Necrosis
Liver Neoplasms Antibodies	>46 publications with PTHRP and Liver Neoplasms

Organs/Tissues associated with PTHRP elisa kit

Organ/Tissue Name	Pubmed Publications
Parathyroid Antibodies	>1195 publications with PTHRP and Parathyroid
Kidney Antibodies	>144 publications with PTHRP and Kidney
Lung Antibodies	>128 publications with PTHRP and Lung
Skin Antibodies	>71 publications with PTHRP and Skin
Embryonic Tissue Antibodies	>59 publications with PTHRP and Embryonic Tissue
Prostate Antibodies	>43 publications with PTHRP and Prostate
Uterus Antibodies	>32 publications with PTHRP and Uterus
Mammary Gland Antibodies	>31 publications with PTHRP and Mammary Gland
Brain Antibodies	>28 publications with PTHRP and Brain
Pancreas Antibodies	>25 publications with PTHRP and Pancreas