Soluble Fms-Like Tyrosine Kinase Receptor 1 (SFLT-1) ELISA Kit for Rat

Name: Rat SFLT-1 ELISA Kit; Soluble Fms-Like Tyrosine Kinase Receptor 1; MyBioSource
Brand: MyBioSource
SKU: MBS007319
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS007319

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used to determine the level of SFLT-1 (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates.… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Soluble Fms-Like Tyrosine Kinase Receptor 1 (SFLT-1), ELISA Kit

Full Product Name

Rat Soluble Fms-Like Tyrosine Kinase Receptor 1 ELISA Kit

Product Gene Name

SFLT-1 elisa kit

Species Reactivity

Rat

Assay Type

Quantitative Sandwich

Samples

Human Body Fluids And Tissue Homogenates

Detection Range

0.625ng/ml-20ng/ml

Sensitivity

0.1ng/ml.

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (?) are less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) are less than 15%

Molecular Weight

149,876 Da

Chromosome Location

Chromosome: 5; NC_000071.6 (147562196..147725988, complement). Location: 5 G; 5 87.01 cM

3D Structure

ModBase 3D Structure for P35969

Other Notes

Small volumes of SFLT-1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SFLT-1 purchase

MBS007319 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Soluble Fms-Like Tyrosine Kinase Receptor 1 (SFLT-1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SFLT-1. The ELISA analytical biochemical technique of the MBS007319 kit is based on SFLT-1 antibody-SFLT-1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SFLT-1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SFLT-1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for SFLT-1. It may not necessarily be applicable to this product.

NCBI GI #

2809071

NCBI GeneID

14254

NCBI Accession #

BAA24499.1

UniProt Primary Accession #

P35969

UniProt Secondary Accession #

O55094; Q61517

UniProt Related Accession #

P35969

NCBI Official Full Name

sFlt-1

NCBI Official Synonym Full Names

FMS-like tyrosine kinase 1

NCBI Official Symbol

Flt1

NCBI Official Synonym Symbols

Flt-1; sFlt1; VEGFR1; VEGFR-1; AI323757

UniProt Protein Name

Vascular endothelial growth factor receptor 1

UniProt Synonym Protein Names

Embryonic receptor kinase 2; Fms-like tyrosine kinase 1; FLT-1; Tyrosine-protein kinase receptor FLT

UniProt Gene Name

Flt1

UniProt Synonym Gene Names

Emrk2; Flt; Vegfr1; VEGFR-1; FLT-1

UniProt Entry Name

VGFR1_MOUSE

NCBI Protein Information

vascular endothelial growth factor receptor 1; embryonic receptor kinase 2; tyrosine-protein kinase receptor FLT; vascular permeability factor receptor; vascular endothelial growth factor receptor-1

UniProt Comments for SFLT-1

VEGFR1: a receptor tyrosine kinase of the VEGFR family. Receptor for VEGF, VEGFB and PGF. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Two splice variant isoforms have been described. Isoform SFlt1 may have an inhibitory role in angiogenesis.

Protein type: Kinase, protein; Protein kinase, tyrosine (receptor); Protein kinase, TK; Membrane protein, integral; EC 2.7.10.1; TK group; VEGFR family

Cellular Component: focal adhesion; membrane; integral to plasma membrane; plasma membrane; integral to membrane; endosome; receptor complex

Molecular Function: transferase activity; identical protein binding; vascular endothelial growth factor receptor activity; protein-tyrosine kinase activity; growth factor binding; transferase activity, transferring phosphorus-containing groups; nucleotide binding; transmembrane receptor protein tyrosine kinase activity; kinase activity; ATP binding; protein kinase activity

Biological Process: cell migration; peptidyl-tyrosine phosphorylation; multicellular organismal development; protein amino acid autophosphorylation; positive regulation of phosphoinositide 3-kinase activity; chemotaxis; protein amino acid phosphorylation; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of phosphoinositide 3-kinase cascade; patterning of blood vessels; positive regulation of MAP kinase activity; monocyte chemotaxis; positive regulation of angiogenesis; positive regulation of MAPKKK cascade; response to hypoxia; blood vessel morphogenesis; embryonic morphogenesis; angiogenesis; sprouting angiogenesis; cell differentiation; vascular endothelial growth factor receptor signaling pathway; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; positive regulation of cell migration

Research Articles on SFLT-1

1. Macrophage Wnt-Calcineurin-Flt1 signaling regulates mouse wound angiogenesis and repair.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with SFLT-1 elisa kit

Products by Pathway	Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram
Focal Adhesion Pathway antibodies	Focal Adhesion Pathway Diagram
Focal Adhesion Pathway antibodies	Focal Adhesion Pathway Diagram
Focal Adhesion Pathway antibodies	Focal Adhesion Pathway Diagram
HIF-1 Signaling Pathway antibodies	HIF-1 Signaling Pathway Diagram
Id Signaling Pathway antibodies	Id Signaling Pathway Diagram
Neurophilin Interactions With VEGF And VEGFR Pathway antibodies	Neurophilin Interactions With VEGF And VEGFR Pathway Diagram

Diseases associated with SFLT-1 elisa kit

Disease Name	Pubmed Publications
Pre-Eclampsia Antibodies	>237 publications with SFLT-1 and Pre-Eclampsia
Neoplasms Antibodies	>204 publications with SFLT-1 and Neoplasms
Hypertension Antibodies	>98 publications with SFLT-1 and Hypertension
Proteinuria Antibodies	>55 publications with SFLT-1 and Proteinuria
Inflammation Antibodies	>45 publications with SFLT-1 and Inflammation
Nervous System Diseases Antibodies	>41 publications with SFLT-1 and Nervous System Diseases
Necrosis Antibodies	>31 publications with SFLT-1 and Necrosis
Brain Diseases Antibodies	>31 publications with SFLT-1 and Brain Diseases
Neoplasms, Experimental Antibodies	>28 publications with SFLT-1 and Neoplasms, Experimental
Heart Diseases Antibodies	>28 publications with SFLT-1 and Heart Diseases

Organs/Tissues associated with SFLT-1 elisa kit

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>116 publications with SFLT-1 and Embryonic Tissue
Muscle Antibodies	>84 publications with SFLT-1 and Muscle
Bone Antibodies	>76 publications with SFLT-1 and Bone
Lung Antibodies	>58 publications with SFLT-1 and Lung
Kidney Antibodies	>53 publications with SFLT-1 and Kidney
Eye Antibodies	>50 publications with SFLT-1 and Eye
Brain Antibodies	>49 publications with SFLT-1 and Brain
Heart Antibodies	>48 publications with SFLT-1 and Heart
Uterus Antibodies	>33 publications with SFLT-1 and Uterus
Intestine Antibodies	>6 publications with SFLT-1 and Intestine