Engrailed Homeobox Protein 2 (EN2) ELISA Kit for Human

Name: Human EN2 ELISA Kit; Engrailed Homeobox Protein 2; MyBioSource
Brand: MyBioSource
SKU: MBS733913
Price: 580 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS733913

MBS733913 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Engrailed Homeobox Protein 2 (EN2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$580 / 48-Strip-Wells-(Competitive) +1 FREE 8GB USB

Product Documentation

Sample Competitive Manual Insert View PDF

Sample Sandwich Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Engrailed Homeobox Protein 2 (EN2), ELISA Kit

Full Product Name

Human Engrailed Homeobox Protein 2 ELISA Kit

Product Gene Name

EN2 elisa kit

Species Reactivity

Human

Assay Type

Competitive or Sandwich

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

1.0-25ng/mL

Sensitivity

0.1ng/mL

Preparation and Storage

Store all reagents at 2-8 degree C.

Molecular Weight

34,211 Da

OMIM

131310

Sample Preparation

We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team

Highest Standards

25ng/mL

Concentration of Standards

Concentration of Standards||0,1,2.5,5.0,10,25ng/mL

Product Categories/Family for EN2 elisa kit

Neurobiology

ISO Certification

Manufactured in an ISO 13485:2016 Certified Laboratory.

Other Notes

Small volumes of EN2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EN2. It may not necessarily be applicable to this product.

NCBI GI #

85397847

NCBI GeneID

2020

NCBI Accession #

AAI04971.1

UniProt Secondary Accession #

Q549U3; Q9UD58; A4D252

UniProt Related Accession #

P19622

NCBI Official Full Name

Engrailed homeobox 2

NCBI Official Synonym Full Names

engrailed homeobox 2

NCBI Official Symbol

EN2

UniProt Protein Name

Homeobox protein engrailed-2

Protein Family

Homeobox protein

UniProt Gene Name

EN2

UniProt Synonym Gene Names

Homeobox protein en-2; Hu-En-2

UniProt Entry Name

HME2_HUMAN

NCBI Protein Information

homeobox protein engrailed-2; hu-En-2; engrailed homolog 2; homeobox protein en-2

NCBI Summary for EN2

Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008]

UniProt Comments for EN2

En-2: Genetic variations in EN2 may be associated with susceptibility to autism. Belongs to the engrailed homeobox family.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 7q36

Cellular Component: membrane; nucleus

Molecular Function: sequence-specific DNA binding

Biological Process: multicellular organismal development; midbrain development; neuron development; positive regulation of transcription from RNA polymerase II promoter; hindbrain development

Disease: Autism, Susceptibility To, 10

Research Articles on EN2

1. urinary EN2 has the potential to be a more sensitive and specific protein biomarker for non-muscle-invasive bladder cancer than currently available tests.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with EN2 elisa kit

Reference Product	PubMed Publications
EN1 elisa kit	>50 publications with EN2 and EN1
PAX2 elisa kit	>15 publications with EN2 and PAX2
GLI3 elisa kit	>1 publications with EN2 and GLI3
FOXA2 elisa kit	>1 publications with EN2 and FOXA2
HPRT1 elisa kit	>1 publications with EN2 and HPRT1

Diseases associated with EN2 elisa kit

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>29 publications with EN2 and Nervous System Diseases
Autistic Disorder Antibodies	>20 publications with EN2 and Autistic Disorder
Congenital Abnormalities Antibodies	>19 publications with EN2 and Congenital Abnormalities
Death Antibodies	>14 publications with EN2 and Death
Brain Diseases Antibodies	>13 publications with EN2 and Brain Diseases
Disease Models, Animal Antibodies	>10 publications with EN2 and Disease Models, Animal
Neurodegenerative Diseases Antibodies	>6 publications with EN2 and Neurodegenerative Diseases
Movement Disorders Antibodies	>5 publications with EN2 and Movement Disorders
Parkinson Disease Antibodies	>3 publications with EN2 and Parkinson Disease
Parkinsonian Disorders Antibodies	>3 publications with EN2 and Parkinsonian Disorders

Organs/Tissues associated with EN2 elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>84 publications with EN2 and Brain
Intestine Antibodies	>2 publications with EN2 and Intestine
Mammary Gland Antibodies	>1 publications with EN2 and Mammary Gland