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Signal Transducer and Activator of Transcription 3 (STAT3) ELISA Kit for Chicken

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS734510

Principle of the Assay: STAT3 ELISA kit applies the competitive enzyme immunoassay technique utilizing a monoclonal anti-STAT3 antibody and an STAT3-HRP conjugate. The assay sample and buffer are incubated together with STAT3-HRP conjugate in pre-coated plate… More details

$580 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Signal Transducer And Activator Of Transcription 3 (STAT3), ELISA Kit
Full Product Name
Chicken Signal Transducer And Activator Of Transcription 3 ELISA Kit
Product Gene Name
STAT3 elisa kit
Species Reactivity
Chicken
Assay Type
Competitive
Samples
Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
Sensitivity
0.1 ng/mL
Preparation and Storage
Store all reagents at 2-8 degree C
Molecular Weight
88,054 Da
Chromosome Location
Chromosome: 11; NC_000077.6 (100886810..100939511, complement). Location: 11 D; 11 60.5 cM
3D Structure
ModBase 3D Structure for P42227
Sample Preparation
We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
Intended Uses
Thisx STAT3 ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Chicken STAT3. This ELISA kit for research use only, not for therapeutic applications!

Product Categories/Family for STAT3 elisa kit

Signal Transduction
ISO Certification
Manufactured in an ISO 13485:2016 Certified Laboratory.

Typical Testing Data/Standard Curve (for reference only) of STAT3 elisa kit

Chicken STAT3 ELISA Kit – Cat# MBS734510

Other Notes

Small volumes of STAT3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STAT3 purchase

MBS734510 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Signal Transducer And Activator Of Transcription 3 (STAT3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing STAT3. The ELISA analytical biochemical technique of the MBS734510 kit is based on STAT3 antibody-STAT3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect STAT3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, STAT3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for STAT3. It may not necessarily be applicable to this product.

NCBI GI #
458706
NCBI GeneID
20848
NCBI Accession #
AAA19452.1
UniProt Primary Accession #
P42227
UniProt Secondary Accession #
A2A5D1; B7ZC17
UniProt Related Accession #
P42227; Q3U5Q4; Q3U6S9; Q3ULI4; Q6GU23; Q8CFJ6; Q99ML3
NCBI Official Full Name
Stat3
NCBI Official Synonym Full Names
signal transducer and activator of transcription 3
NCBI Official Symbol
Stat3
NCBI Official Synonym Symbols
Aprf; AW109958; 1110034C02Rik
UniProt Protein Name
Signal transducer and activator of transcription 3
UniProt Synonym Protein Names
Acute-phase response factor
Protein Family
Signal transducer and activator of transcription
UniProt Gene Name
Stat3
UniProt Synonym Gene Names
Aprf
UniProt Entry Name
STAT3_MOUSE
NCBI Protein Information
signal transducer and activator of transcription 3; acute phase response factor; acute-phase response factor

UniProt Comments for STAT3

STAT3: transcription factor of the STAT family. Phosphorylated and activated by receptor-associated kinases downstream of many cytokines and growth-factor receptors. Constitutively active in a number of human tumors. Forms homo- or heterodimers that translocate into the nucleus where they regulate transcription. Two alternatively spliced isoforms have been described.

Protein type: Nuclear receptor co-regulator; Transcription factor; Motility/polarity/chemotaxis; DNA-binding

Cellular Component: nucleoplasm; mitochondrion; mitochondrial inner membrane; cytoplasm; plasma membrane; intracellular; nucleus

Molecular Function: protein dimerization activity; protein binding; ligand-dependent nuclear receptor activity; signal transducer activity; DNA binding; sequence-specific DNA binding; transcription factor binding; protein phosphatase binding; transcription factor activity; protein kinase binding; glucocorticoid receptor binding; CCR5 chemokine receptor binding

Biological Process: transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; radial glial cell differentiation; thermoregulation; signal transduction; glucose homeostasis; response to estradiol stimulus; negative regulation of cell proliferation; regulation of transcription, DNA-dependent; astrocyte differentiation; protein import into nucleus; acute-phase response; negative regulation of glycolysis; positive regulation of Notch signaling pathway; intracellular receptor-mediated signaling pathway; transcription, DNA-dependent; eating behavior; cytokine and chemokine mediated signaling pathway; stem cell maintenance; regulation of multicellular organism growth; JAK-STAT cascade; cellular response to hormone stimulus; cell proliferation; sexual reproduction; response to cytokine stimulus; positive regulation of transcription from RNA polymerase II promoter; regulation of mitochondrial membrane permeability; eye photoreceptor cell differentiation; phosphorylation
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Research Articles on STAT3

1. Results support a role for STAT3 in metabolic, synaptic, structural and transcriptional responses to cerebral ischemia

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with STAT3 elisa kit

 Reference Product  PubMed Publications
 Src elisa kit  >625 publications with STAT3 and Src
 Jak1 elisa kit  >488 publications with STAT3 and Jak1
 Jun elisa kit  >268 publications with STAT3 and Jun
 Il6st elisa kit  >255 publications with STAT3 and Il6st
 Map3k1 elisa kit  >10 publications with STAT3 and Map3k1
 Prkcd elisa kit  >7 publications with STAT3 and Prkcd
 Pik3r1 elisa kit  >2 publications with STAT3 and Pik3r1
 Isl1 elisa kit  >1 publications with STAT3 and Isl1

Pathways associated with STAT3 elisa kit

 Products by Pathway  Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram

Diseases associated with STAT3 elisa kit

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >2854 publications with STAT3 and Neoplasms
 Inflammation Antibodies  >1102 publications with STAT3 and Inflammation
 Cardiovascular Diseases Antibodies  >612 publications with STAT3 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >602 publications with STAT3 and Disease Models, Animal
 Necrosis Antibodies  >572 publications with STAT3 and Necrosis
 Adenocarcinoma Antibodies  >457 publications with STAT3 and Adenocarcinoma
 Liver Diseases Antibodies  >427 publications with STAT3 and Liver Diseases
 Nervous System Diseases Antibodies  >384 publications with STAT3 and Nervous System Diseases
 Gastrointestinal Diseases Antibodies  >370 publications with STAT3 and Gastrointestinal Diseases
 Neoplasms, Experimental Antibodies  >329 publications with STAT3 and Neoplasms, Experimental

Organs/Tissues associated with STAT3 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1896 publications with STAT3 and Blood
 Other Antibodies  >1253 publications with STAT3 and Other
 Liver Antibodies  >922 publications with STAT3 and Liver
 Brain Antibodies  >735 publications with STAT3 and Brain
 Muscle Antibodies  >563 publications with STAT3 and Muscle
 Bone Antibodies  >526 publications with STAT3 and Bone
 Lung Antibodies  >501 publications with STAT3 and Lung
 Heart Antibodies  >397 publications with STAT3 and Heart
 Bone Marrow Antibodies  >363 publications with STAT3 and Bone Marrow
 Skin Antibodies  >330 publications with STAT3 and Skin
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