Prolylcarboxypeptidase (PRCP) ELISA Kit for Chicken

Name: Chicken PRCP ELISA Kit; Prolylcarboxypeptidase; MyBioSource
Brand: MyBioSource
SKU: MBS736456
Price: 580 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS736456

MBS736456 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Prolylcarboxypeptidase (PRCP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards… More details

$580 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Prolylcarboxypeptidase (PRCP), ELISA Kit

Full Product Name

Chicken Prolylcarboxypeptidase ELISA Kit

Product Gene Name

PRCP elisa kit

Species Reactivity

Chicken

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

55,800 Da

Chromosome Location

Chromosome: 11; NC_000011.9 (82535409..82611557, complement). Location: 11q14

OMIM

176785

3D Structure

ModBase 3D Structure for P42785

Sample Preparation

We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team

Product Categories/Family for PRCP elisa kit

Cell Biology

ISO Certification

Manufactured in an ISO 13485:2016 Certified Laboratory.

Other Notes

Small volumes of PRCP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PRCP. It may not necessarily be applicable to this product.

NCBI GI #

431321

NCBI GeneID

5547

NCBI Accession #

AAA99891.1

UniProt Primary Accession #

P42785

UniProt Secondary Accession #

B2R7B7; B5BU34

UniProt Related Accession #

P42785

NCBI Official Full Name

prolylcarboxypeptidase

NCBI Official Synonym Full Names

prolylcarboxypeptidase (angiotensinase C)

NCBI Official Symbol

PRCP

NCBI Official Synonym Symbols

PCP; HUMPCP

UniProt Protein Name

Lysosomal Pro-X carboxypeptidase

UniProt Synonym Protein Names

Angiotensinase C; Lysosomal carboxypeptidase C; Proline carboxypeptidase; Prolylcarboxypeptidase

Protein Family

Lysosomal Pro-X carboxypeptidase

UniProt Gene Name

PRCP

UniProt Synonym Gene Names

PCP; PRCP

UniProt Entry Name

PCP_HUMAN

NCBI Protein Information

lysosomal Pro-X carboxypeptidase; angiotensinase C; proline carboxypeptidase; lysosomal carboxypeptidase C; prolylcarboxypeptidase isoform 1 preproprotein

NCBI Summary for PRCP

The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

UniProt Comments for PRCP

PRCP: Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. Belongs to the peptidase S28 family.

Protein type: Protease; EC 3.4.16.2

Chromosomal Location of Human Ortholog: 11q14

Cellular Component: lysosome; plasma membrane

Molecular Function: serine carboxypeptidase activity; protein binding

Biological Process: negative regulation of systemic arterial blood pressure; plasma kallikrein-kinin cascade; blood coagulation; regulation of blood vessel endothelial cell migration; glucose homeostasis; proteolysis; angiogenesis involved in wound healing; blood coagulation, intrinsic pathway

Research Articles on PRCP

1. PRCP as a resistance factor for 4OHTAM resistance in estrogen receptor-positive breast cancer cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PRCP elisa kit

Products by Pathway	Pathway Diagram
Formation Of Fibrin Clot (Clotting Cascade) Pathway antibodies	Formation Of Fibrin Clot (Clotting Cascade) Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Intrinsic Pathway antibodies	Intrinsic Pathway Diagram
Protein Digestion And Absorption Pathway antibodies	Protein Digestion And Absorption Pathway Diagram
Protein Digestion And Absorption Pathway antibodies	Protein Digestion And Absorption Pathway Diagram

Diseases associated with PRCP elisa kit

Disease Name	Pubmed Publications
Hypertension Antibodies	>9 publications with PRCP and Hypertension
Vascular Diseases Antibodies	>8 publications with PRCP and Vascular Diseases
Thrombosis Antibodies	>3 publications with PRCP and Thrombosis
Cerebrovascular Disorders Antibodies	>2 publications with PRCP and Cerebrovascular Disorders
Brain Diseases Antibodies	>2 publications with PRCP and Brain Diseases
Infection Antibodies	>2 publications with PRCP and Infection
Kidney Diseases Antibodies	>2 publications with PRCP and Kidney Diseases
Shock Antibodies	>1 publications with PRCP and Shock
Respiratory Tract Infections Antibodies	>1 publications with PRCP and Respiratory Tract Infections
Arthritis, Rheumatoid Antibodies	>1 publications with PRCP and Arthritis, Rheumatoid

Organs/Tissues associated with PRCP elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>14 publications with PRCP and Blood
Brain Antibodies	>14 publications with PRCP and Brain
Vascular Antibodies	>10 publications with PRCP and Vascular
Heart Antibodies	>4 publications with PRCP and Heart
Embryonic Tissue Antibodies	>3 publications with PRCP and Embryonic Tissue
Kidney Antibodies	>2 publications with PRCP and Kidney
Thyroid Antibodies	>2 publications with PRCP and Thyroid
Lung Antibodies	>2 publications with PRCP and Lung
Liver Antibodies	>2 publications with PRCP and Liver
Bone Antibodies	>2 publications with PRCP and Bone