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High Mobility Group Nucleosome Binding Domain 1 (HMGN1) ELISA Kit for Chicken

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS736684

MBS736684 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the High Mobility Group Nucleosome Binding Domain 1 (HMGN1) ELISA Kit target analytes in biological samples. The concentration… More details

$580 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
High Mobility Group Nucleosome Binding Domain 1 (HMGN1), ELISA Kit
Full Product Name
Chicken High Mobility Group Nucleosome Binding Domain 1 ELISA Kit
Product Gene Name
HMGN1 elisa kit
Species Reactivity
Chicken
Preparation and Storage
Store all reagents at 2-8 degree C
Molecular Weight
10,659 Da
Chromosome Location
Chromosome: 21; NC_000021.8 (40714241..40721047, complement). Location: 21q22.2
OMIM
163920
3D Structure
ModBase 3D Structure for P05114
Sample Preparation
We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team

Product Categories/Family for HMGN1 elisa kit

Cancer
ISO Certification
Manufactured in an ISO 13485:2016 Certified Laboratory.

Other Notes

Small volumes of HMGN1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HMGN1. It may not necessarily be applicable to this product.

NCBI GI #
18645182
NCBI GeneID
3150
NCBI Accession #
AAH23984.1
UniProt Primary Accession #
P05114
UniProt Secondary Accession #
Q3KQR8
UniProt Related Accession #
P05114; Q3B790; Q6NSG7; Q96N32
NCBI Official Full Name
High-mobility group nucleosome binding domain 1
NCBI Official Synonym Full Names
high mobility group nucleosome binding domain 1
NCBI Official Symbol
HMGN1
NCBI Official Synonym Symbols
HMG14
UniProt Protein Name
Non-histone chromosomal protein HMG-14
UniProt Synonym Protein Names
High mobility group nucleosome-binding domain-containing protein 1
Protein Family
Non-histone chromosomal protein
UniProt Gene Name
HMGN1
UniProt Synonym Gene Names
HMG14
UniProt Entry Name
HMGN1_HUMAN
NCBI Protein Information
non-histone chromosomal protein HMG-14; nonhistone chromosomal protein HMG-14; high-mobility group nucleosome binding 1; high-mobility group nucleosome binding domain 1; high-mobility group (nonhistone chromosomal) protein 14; high mobility group nucleosome-binding domain-containing protein 1

NCBI Summary for HMGN1

The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes. [provided by RefSeq, Aug 2011]

UniProt Comments for HMGN1

HMGN1: a nonhistone chromosomal protein of the HMG-14/HMG-17 protein family. Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation.

Protein type: DNA-binding; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 21q22.2

Cellular Component: cytoplasm; nucleus; chromatin

Molecular Function: nucleosomal DNA binding; DNA binding

Biological Process: regulation of transcription from RNA polymerase II promoter; establishment and/or maintenance of chromatin architecture; positive regulation of RNA elongation; transcription-coupled nucleotide-excision repair; pyrimidine dimer repair via nucleotide-excision repair; regulation of development, heterochronic; post-embryonic camera-type eye morphogenesis; response to UV-C; regulation of epithelial cell proliferation; response to UV-B
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Research Articles on HMGN1

1. extracellular HMGN1 acts as a novel alarmin critical for LPS-induced development of innate and adaptive immune responses.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HMGN1 elisa kit

 Reference Product  PubMed Publications
 HMGN2 elisa kit  >133 publications with HMGN1 and HMGN2
 RPS6KA4 elisa kit  >2 publications with HMGN1 and RPS6KA4

Pathways associated with HMGN1 elisa kit

 Products by Pathway  Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 P38 MAPK Signaling Pathway antibodies  P38 MAPK Signaling Pathway Diagram

Diseases associated with HMGN1 elisa kit

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >36 publications with HMGN1 and Neoplasms
 Carcinoma Antibodies  >8 publications with HMGN1 and Carcinoma
 Congenital Abnormalities Antibodies  >7 publications with HMGN1 and Congenital Abnormalities
 Cell Transformation, Neoplastic Antibodies  >5 publications with HMGN1 and Cell Transformation, Neoplastic
 Cardiovascular Diseases Antibodies  >5 publications with HMGN1 and Cardiovascular Diseases
 Liver Diseases Antibodies  >3 publications with HMGN1 and Liver Diseases
 Learning Disorders Antibodies  >3 publications with HMGN1 and Learning Disorders
 Liver Neoplasms Antibodies  >3 publications with HMGN1 and Liver Neoplasms
 Liver Neoplasms, Experimental Antibodies  >3 publications with HMGN1 and Liver Neoplasms, Experimental
 Gastrointestinal Diseases Antibodies  >2 publications with HMGN1 and Gastrointestinal Diseases

Organs/Tissues associated with HMGN1 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >51 publications with HMGN1 and Blood
 Thymus Antibodies  >47 publications with HMGN1 and Thymus
 Liver Antibodies  >30 publications with HMGN1 and Liver
 Brain Antibodies  >17 publications with HMGN1 and Brain
 Thyroid Antibodies  >10 publications with HMGN1 and Thyroid
 Heart Antibodies  >10 publications with HMGN1 and Heart
 Muscle Antibodies  >9 publications with HMGN1 and Muscle
 Testis Antibodies  >9 publications with HMGN1 and Testis
 Spleen Antibodies  >8 publications with HMGN1 and Spleen
 Lung Antibodies  >7 publications with HMGN1 and Lung
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