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Cyclin Dependent Kinase 2 (CDK-2) ELISA Kit for Chicken

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS739602

MBS739602 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cyclin Dependent Kinase 2 (CDK-2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$580 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cyclin Dependent Kinase 2 (CDK-2), ELISA Kit
Full Product Name
Chicken Cyclin Dependent Kinase 2 ELISA Kit
Product Gene Name
CDK-2 elisa kit
Species Reactivity
Chicken
Samples
Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
Preparation and Storage
Store all reagents at 2-8 degree C.
Molecular Weight
– Da
Sample Preparation
We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team

Product Categories/Family for CDK-2 elisa kit

Immunology
ISO Certification
Manufactured in an ISO 13485:2016 Certified Laboratory.

Other Notes

Small volumes of CDK-2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CDK-2. It may not necessarily be applicable to this product.

NCBI GI #
41054836
NCBI GeneID
362817
NCBI Accession #
NP_955795.1
UniProt Secondary Accession #
O09136
UniProt Related Accession #
Q63699
GenBank Nucleotide #
NM_199501.1
NCBI Official Full Name
cyclin-dependent kinase 2
NCBI Official Synonym Full Names
cyclin dependent kinase 2
NCBI Official Symbol
Cdk2
UniProt Protein Name
Cyclin-dependent kinase 2
UniProt Synonym Protein Names
Cell division protein kinase 2
Protein Family
Cyclin-dependent kinase 2-associated protein
UniProt Gene Name
Cdk2
UniProt Synonym Gene Names
Cdkn2
UniProt Entry Name
CDK2_RAT
NCBI Protein Information
cyclin-dependent kinase 2; cell division protein kinase 2; cyclin dependent kinase 2-alpha

UniProt Comments for CDK-2

CDK2: a protein kinase of the CDK family. An important component of the cell cycle machinery. Activity of CDK2 is maximal during S phase and G2. Cdk2/cyclin E kinase activity is important for the G1 to S transition and phosphorylates the Rb protein. In S-phase, active cdk2/cyclin A complexes predominate and phosphorylate E2F, and the active cdk2 complex persists in the nucleus through G2. Part of the Rb pathway disregulated in most tumors. Target of several candidate cancer drugs. However, inhibition does not always prevent cancer cell growth, possibly due to CDK redundancy. Inhibitors: BMS-265246, BMS-265246-01, R-roscovitine (CYC200, CYC202), SU9516, R547, L868276

Protein type: Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Cell cycle regulation; Protein kinase, CMGC; EC 2.7.11.22; CMGC group; CDK family; CDK1 subfamily; CDK/CDK1 subfamily

Cellular Component: Y chromosome; Cajal body; chromosome, telomeric region; transcription factor complex; intracellular membrane-bound organelle; X chromosome; cytoplasm; cyclin-dependent protein kinase holoenzyme complex; microtubule organizing center; condensed chromosome; cytosol; nucleus; endosome

Molecular Function: cyclin binding; cyclin-dependent protein kinase activity; metal ion binding; protein complex binding; histone kinase activity; kinase activity; ATP binding; protein kinase activity

Biological Process: response to drug; lens development in camera-type eye; mitosis; organ regeneration; response to cAMP; regulation of cell cycle; response to toxin; positive regulation of transcription, DNA-dependent; histone phosphorylation; DNA repair; protein amino acid phosphorylation; response to estradiol stimulus; peptidyl-serine phosphorylation; response to cadmium ion; response to ethanol; meiotic cell cycle; cellular response to insulin stimulus; cell division; positive regulation of cell proliferation; Ras protein signal transduction; response to electrical stimulus; potassium ion transport; positive regulation of DNA replication initiation; G1/S transition of mitotic cell cycle
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Research Articles on CDK-2

1. The Irf-1 overexpression-induced proliferation of VSMCs, the up-regulation of cyclin E/CDK2 and the acceleration of cell cycle progression are associated with ROS/Erk1/2 signaling pathway under high glucose conditions.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CDK-2 elisa kit

 Products by Pathway  Pathway Diagram
 APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies  APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
 ATM Pathway antibodies  ATM Pathway Diagram
 Activation Of ATR In Response To Replication Stress Pathway antibodies  Activation Of ATR In Response To Replication Stress Pathway Diagram
 Activation Of The Pre-replicative Complex Pathway antibodies  Activation Of The Pre-replicative Complex Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 CDK-mediated Phosphorylation And Removal Of Cdc6 Pathway antibodies  CDK-mediated Phosphorylation And Removal Of Cdc6 Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram

Organs/Tissues associated with CDK-2 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >291 publications with CDK-2 and Liver
 Lung Antibodies  >235 publications with CDK-2 and Lung
 Prostate Antibodies  >165 publications with CDK-2 and Prostate
 Brain Antibodies  >159 publications with CDK-2 and Brain
 Colon Antibodies  >148 publications with CDK-2 and Colon
 Embryonic Tissue Antibodies  >96 publications with CDK-2 and Embryonic Tissue
 Heart Antibodies  >81 publications with CDK-2 and Heart
 Thymus Antibodies  >31 publications with CDK-2 and Thymus
 Spleen Antibodies  >31 publications with CDK-2 and Spleen
 Pancreas Antibodies  >25 publications with CDK-2 and Pancreas
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