Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2) ELISA Kit for Goat

Name: Goat NR1D2 ELISA Kit; Nuclear Receptor Subfamily 1, Group D, Member 2; MyBioSource
Brand: MyBioSource
SKU: MBS074290
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS074290

MBS074290 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2) ELISA Kit target analytes in biological samples. The… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2), ELISA Kit

Full Product Name

Goat Nuclear Receptor Subfamily 1, Group D, Member 2 ELISA Kit

Product Gene Name

NR1D2 elisa kit

Species Reactivity

Goat

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

64,625 Da

OMIM

602304

3D Structure

ModBase 3D Structure for Q14995

Other Notes

Small volumes of NR1D2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NR1D2. It may not necessarily be applicable to this product.

NCBI GI #

224177491

NCBI GeneID

9975

NCBI Accession #

NP_005117.3

UniProt Primary Accession #

Q14995

UniProt Secondary Accession #

O00402; Q86XD4; B2R8Q3

UniProt Related Accession #

Q14995

GenBank Nucleotide #

NM_005126.4

NCBI Official Full Name

nuclear receptor subfamily 1 group D member 2 isoform 1

NCBI Official Synonym Full Names

nuclear receptor subfamily 1, group D, member 2

NCBI Official Symbol

NR1D2

NCBI Official Synonym Symbols

RVR; BD73; EAR-1R

UniProt Protein Name

Nuclear receptor subfamily 1 group D member 2

UniProt Synonym Protein Names

Orphan nuclear hormone receptor BD73; Rev-erb alpha-related receptor; RVR; Rev-erb-beta; V-erbA-related protein 1-related

Protein Family

Nuclear receptor subfamily

UniProt Gene Name

NR1D2

UniProt Synonym Gene Names

RVR; EAR-1R

UniProt Entry Name

NR1D2_HUMAN

NCBI Protein Information

nuclear receptor subfamily 1 group D member 2; rev-erb-beta; rev-erb alpha-related receptor; rev-erba-alpha-related receptor; V-erbA-related protein 1-related; orphan nuclear hormone receptor BD73; nuclear receptor Rev-ErbA beta variant 1; nuclear receptor Rev-ErbA beta variant 2

NCBI Summary for NR1D2

This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]

UniProt Comments for NR1D2

NR1D2: Binds to the sequences 5'-AATGTAGGTCA-3' and 5'- ATAACTAGGTCA-3'. Acts as a potent competitive repressor of ROR alpha function. Belongs to the nuclear hormone receptor family. NR1 subfamily.

Protein type: DNA-binding; Nuclear receptor

Chromosomal Location of Human Ortholog: 3p24.2

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; ligand-dependent nuclear receptor activity; zinc ion binding; steroid hormone receptor activity

Biological Process: transcription initiation from RNA polymerase II promoter; intracellular receptor-mediated signaling pathway; regulation of lipid metabolic process; regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; regulation of inflammatory response; rhythmic process; lipid homeostasis; steroid hormone mediated signaling; gene expression; regulation of circadian rhythm; negative regulation of transcription, DNA-dependent

Research Articles on NR1D2

1. Our results suggest that the REV-ERBalpha rs2071427 polymorphism modulates body fat mass in both adult and young people.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NR1D2 elisa kit

Reference Product	PubMed Publications
NR1D1 elisa kit	>24 publications with NR1D2 and NR1D1
RORA elisa kit	>3 publications with NR1D2 and RORA
RORC elisa kit	>2 publications with NR1D2 and RORC
THRB elisa kit	>1 publications with NR1D2 and THRB
THRA elisa kit	>1 publications with NR1D2 and THRA
NCOR1 elisa kit	>1 publications with NR1D2 and NCOR1

Pathways associated with NR1D2 elisa kit

Products by Pathway	Pathway Diagram
Diurnally Regulated Genes With Circadian Orthologs Pathway antibodies	Diurnally Regulated Genes With Circadian Orthologs Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Generic Transcription Pathway antibodies	Generic Transcription Pathway Diagram
Nuclear Receptor Transcription Pathway antibodies	Nuclear Receptor Transcription Pathway Diagram
Nuclear Receptors Pathway antibodies	Nuclear Receptors Pathway Diagram

Diseases associated with NR1D2 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>5 publications with NR1D2 and Inflammation
Disease Models, Animal Antibodies	>4 publications with NR1D2 and Disease Models, Animal
Nervous System Diseases Antibodies	>3 publications with NR1D2 and Nervous System Diseases
Neoplasms Antibodies	>2 publications with NR1D2 and Neoplasms
Liver Diseases Antibodies	>2 publications with NR1D2 and Liver Diseases
Cardiovascular Diseases Antibodies	>1 publications with NR1D2 and Cardiovascular Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with NR1D2 and Carcinoma, Hepatocellular
Hyperplasia Antibodies	>1 publications with NR1D2 and Hyperplasia
Hypertrophy Antibodies	>1 publications with NR1D2 and Hypertrophy
Fatty Liver Antibodies	>1 publications with NR1D2 and Fatty Liver

Organs/Tissues associated with NR1D2 elisa kit

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>10 publications with NR1D2 and Muscle
Liver Antibodies	>9 publications with NR1D2 and Liver
Blood Antibodies	>5 publications with NR1D2 and Blood
Brain Antibodies	>5 publications with NR1D2 and Brain
Adipose Tissue Antibodies	>4 publications with NR1D2 and Adipose Tissue
Thyroid Antibodies	>4 publications with NR1D2 and Thyroid
Connective Tissue Antibodies	>3 publications with NR1D2 and Connective Tissue
Nerve Antibodies	>2 publications with NR1D2 and Nerve
Kidney Antibodies	>1 publications with NR1D2 and Kidney
Bone Antibodies	>1 publications with NR1D2 and Bone